FR2342974A1 - Procede d'enlevement de groupes de protection du radical carboxy dans les cephalosporines et nouveaux produits ainsi obtenus - Google Patents
Procede d'enlevement de groupes de protection du radical carboxy dans les cephalosporines et nouveaux produits ainsi obtenusInfo
- Publication number
- FR2342974A1 FR2342974A1 FR7706135A FR7706135A FR2342974A1 FR 2342974 A1 FR2342974 A1 FR 2342974A1 FR 7706135 A FR7706135 A FR 7706135A FR 7706135 A FR7706135 A FR 7706135A FR 2342974 A1 FR2342974 A1 FR 2342974A1
- Authority
- FR
- France
- Prior art keywords
- cephalosporins
- procedure
- new products
- protection groups
- removing protection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2360276A JPS52106891A (en) | 1976-03-03 | 1976-03-03 | Removal of carboxyl protecting group |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2342974A1 true FR2342974A1 (fr) | 1977-09-30 |
FR2342974B1 FR2342974B1 (fr) | 1980-07-18 |
Family
ID=12115141
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7706135A Granted FR2342974A1 (fr) | 1976-03-03 | 1977-03-02 | Procede d'enlevement de groupes de protection du radical carboxy dans les cephalosporines et nouveaux produits ainsi obtenus |
Country Status (10)
Country | Link |
---|---|
US (1) | US4223132A (fr) |
JP (1) | JPS52106891A (fr) |
BE (1) | BE852054A (fr) |
CA (1) | CA1069886A (fr) |
CH (1) | CH630333A5 (fr) |
DE (1) | DE2709292A1 (fr) |
FR (1) | FR2342974A1 (fr) |
GB (1) | GB1569040A (fr) |
NL (1) | NL188411C (fr) |
SE (1) | SE443563B (fr) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4708956A (en) * | 1985-12-12 | 1987-11-24 | Kyowa Hakko Kogyo Co., Ltd. | 3-position halogenated cephalosporin analogs and pharmaceutical compositions |
US4734494A (en) * | 1979-11-14 | 1988-03-29 | Kyowa Hakko Kogyo Co., Ltd. | Optically active 3-halo carbacephems |
EP0557035A2 (fr) * | 1992-02-18 | 1993-08-25 | Eli Lilly And Company | Procédé pour la scission d'esters de bêta-lactames |
WO1997017352A1 (fr) * | 1995-11-06 | 1997-05-15 | Gist-Brocades B.V. | Procede de desesterification |
US5922861A (en) * | 1995-11-06 | 1999-07-13 | Gist-Brocades B.V. | De-esterification process |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2725519A1 (de) * | 1977-06-06 | 1978-12-21 | Shionogi & Co | Verfahren zur herstellung freier carbonsaeuren durch esterspaltung |
DE3165543D1 (en) * | 1980-06-11 | 1984-09-20 | Beecham Group Plc | Process for the preparation of beta-lactam antibiotics |
GR79944B (fr) * | 1983-07-22 | 1984-10-31 | Lilly Co Eli | |
JP4138911B2 (ja) * | 1997-06-24 | 2008-08-27 | 大塚化学ホールディングス株式会社 | β−ラクタム誘導体の製造法 |
GB9802877D0 (en) * | 1998-02-12 | 1998-04-08 | Univ St Andrews | Method of chemical cleavage |
CN103254028A (zh) * | 2013-05-14 | 2013-08-21 | 重庆大学 | 一种羧酸苄酯去苄基保护合成羧酸的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3275626A (en) * | 1962-07-31 | 1966-09-27 | Lilly Co Eli | Penicillin conversion via sulfoxide |
US3799924A (en) * | 1970-12-18 | 1974-03-26 | Lilly Co Eli | Ester cleavage process |
US3781282A (en) * | 1971-01-20 | 1973-12-25 | W Garbrecht | Cephalosporin process and product |
US4091214A (en) * | 1977-02-25 | 1978-05-23 | Eli Lilly And Company | De-esterification process for cephalosporins |
-
1976
- 1976-03-03 JP JP2360276A patent/JPS52106891A/ja active Pending
-
1977
- 1977-03-01 CA CA272,878A patent/CA1069886A/fr not_active Expired
- 1977-03-02 SE SE7702307A patent/SE443563B/xx not_active IP Right Cessation
- 1977-03-02 NL NLAANVRAGE7702242,A patent/NL188411C/xx not_active IP Right Cessation
- 1977-03-02 FR FR7706135A patent/FR2342974A1/fr active Granted
- 1977-03-03 GB GB9103/77A patent/GB1569040A/en not_active Expired
- 1977-03-03 BE BE175448A patent/BE852054A/fr not_active IP Right Cessation
- 1977-03-03 CH CH268477A patent/CH630333A5/de not_active IP Right Cessation
- 1977-03-03 DE DE19772709292 patent/DE2709292A1/de active Granted
- 1977-07-25 US US05/818,597 patent/US4223132A/en not_active Expired - Lifetime
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4734494A (en) * | 1979-11-14 | 1988-03-29 | Kyowa Hakko Kogyo Co., Ltd. | Optically active 3-halo carbacephems |
US4708956A (en) * | 1985-12-12 | 1987-11-24 | Kyowa Hakko Kogyo Co., Ltd. | 3-position halogenated cephalosporin analogs and pharmaceutical compositions |
EP0557035A2 (fr) * | 1992-02-18 | 1993-08-25 | Eli Lilly And Company | Procédé pour la scission d'esters de bêta-lactames |
EP0557035A3 (en) * | 1992-02-18 | 1993-12-01 | Lilly Co Eli | An ester cleavage process for use with beta-lactams |
WO1997017352A1 (fr) * | 1995-11-06 | 1997-05-15 | Gist-Brocades B.V. | Procede de desesterification |
US5922861A (en) * | 1995-11-06 | 1999-07-13 | Gist-Brocades B.V. | De-esterification process |
Also Published As
Publication number | Publication date |
---|---|
BE852054A (fr) | 1977-09-05 |
SE443563B (sv) | 1986-03-03 |
JPS52106891A (en) | 1977-09-07 |
US4223132A (en) | 1980-09-16 |
DE2709292C2 (fr) | 1987-12-03 |
NL188411C (nl) | 1992-06-16 |
GB1569040A (en) | 1980-06-11 |
CH630333A5 (de) | 1982-06-15 |
SE7702307L (sv) | 1977-09-04 |
CA1069886A (fr) | 1980-01-15 |
NL7702242A (nl) | 1977-09-06 |
FR2342974B1 (fr) | 1980-07-18 |
DE2709292A1 (de) | 1977-09-08 |
NL188411B (nl) | 1992-01-16 |
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