FR2342290A1 - Aminoalkylpyrrolobenzoxo-aza-alcanes, leur preparation et leurs applications - Google Patents

Aminoalkylpyrrolobenzoxo-aza-alcanes, leur preparation et leurs applications

Info

Publication number
FR2342290A1
FR2342290A1 FR7705370A FR7705370A FR2342290A1 FR 2342290 A1 FR2342290 A1 FR 2342290A1 FR 7705370 A FR7705370 A FR 7705370A FR 7705370 A FR7705370 A FR 7705370A FR 2342290 A1 FR2342290 A1 FR 2342290A1
Authority
FR
France
Prior art keywords
aminoalkylpyrrolobenzoxo
aza
alkanes
applications
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7705370A
Other languages
English (en)
Other versions
FR2342290B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of FR2342290A1 publication Critical patent/FR2342290A1/fr
Application granted granted Critical
Publication of FR2342290B1 publication Critical patent/FR2342290B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333Radicals substituted by oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR7705370A 1976-02-26 1977-02-24 Aminoalkylpyrrolobenzoxo-aza-alcanes, leur preparation et leurs applications Granted FR2342290A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/661,505 US4029672A (en) 1976-02-26 1976-02-26 Aminoalkylpyrrolobenzoxazalkanes

Publications (2)

Publication Number Publication Date
FR2342290A1 true FR2342290A1 (fr) 1977-09-23
FR2342290B1 FR2342290B1 (fr) 1980-02-15

Family

ID=24653884

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7705370A Granted FR2342290A1 (fr) 1976-02-26 1977-02-24 Aminoalkylpyrrolobenzoxo-aza-alcanes, leur preparation et leurs applications

Country Status (13)

Country Link
US (3) US4029672A (fr)
JP (1) JPS52125195A (fr)
BE (1) BE851915A (fr)
CA (1) CA1087181A (fr)
CH (1) CH634576A5 (fr)
DE (1) DE2708111A1 (fr)
DK (1) DK84077A (fr)
FR (1) FR2342290A1 (fr)
GB (1) GB1577342A (fr)
IE (1) IE45651B1 (fr)
IT (1) IT1075298B (fr)
LU (1) LU76838A1 (fr)
NL (1) NL7701832A (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029672A (en) * 1976-02-26 1977-06-14 American Hoechst Corporation Aminoalkylpyrrolobenzoxazalkanes
US4112112A (en) * 1976-06-29 1978-09-05 Merck & Co., Inc. Pyrrolo[2,1-b] [3]benzazepines useful for producing a skeletal muscle relaxing or tranquilizing effect
US4169094A (en) * 1977-01-19 1979-09-25 American Hoechst Corporation Process for preparing aminoalkylpyrrolobenzoxazalkanes
US4169095A (en) * 1977-01-19 1979-09-25 American Hoechst Corporation Process for preparing aminoalkylpyrrolobenzoxazalkanes
US4608374A (en) * 1983-11-07 1986-08-26 Hoechst-Roussel Pharmaceuticals Inc. 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents
US4681879A (en) * 1983-11-07 1987-07-21 Hoechst-Roussel Pharmaceuticals Inc. 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents
US4833244A (en) * 1985-04-22 1989-05-23 Hoechst-Rouseel Pharmaceuticals Inc. Ethanobenzazepines
US4758559A (en) * 1986-01-21 1988-07-19 Ciba-Geigy Corporation Pyrrolo[1,2-a] [4,1]benzoxazepine derivatives useful as calmodulin and histamine inhibitors
US4865764A (en) * 1987-07-20 1989-09-12 Hoechst-Roussel Pharmaceuticals, Inc. 5-aryl-11-substituted-5H,11H-pyrrolo[2,1-][1,4]benzoxazepines as hypotensive agents
US5015637A (en) * 1990-05-25 1991-05-14 Hoechst-Roussel Pharmaceutical Inc. Pyrido[3,4-b]pyrrolo[1,2-e][1,4,5]oxadiazepines
WO1995018092A1 (fr) * 1993-12-28 1995-07-06 Maruho Co., Ltd. Derive de l'aminocetone
AUPP433398A0 (en) * 1998-06-25 1998-07-16 Australian National University, The Compounds and processes

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1154742A (en) * 1966-05-17 1969-06-11 Whitefin Holding Sa Pyrrylamino Ketones
JPS4812756B1 (fr) * 1970-12-25 1973-04-23
BE795451A (fr) * 1972-02-23 1973-08-16 Pfizer Agents hypoglycemiants aza indoliques tricycliques
US4029672A (en) * 1976-02-26 1977-06-14 American Hoechst Corporation Aminoalkylpyrrolobenzoxazalkanes
US4053599A (en) * 1976-02-26 1977-10-11 American Hoechst Corporation Piperazionalkylpyrrolobenzoxazalkanes

Also Published As

Publication number Publication date
FR2342290B1 (fr) 1980-02-15
CH634576A5 (de) 1983-02-15
BE851915A (fr) 1977-08-29
JPS52125195A (en) 1977-10-20
NL7701832A (nl) 1977-08-30
IE45651L (en) 1977-08-26
DK84077A (da) 1977-08-27
GB1577342A (en) 1980-10-22
US4107187A (en) 1978-08-15
US4029672A (en) 1977-06-14
DE2708111A1 (de) 1977-09-01
JPS613351B2 (fr) 1986-01-31
LU76838A1 (fr) 1977-09-12
IT1075298B (it) 1985-04-22
US4107074A (en) 1978-08-15
CA1087181A (fr) 1980-10-07
IE45651B1 (en) 1982-10-20

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Legal Events

Date Code Title Description
ST Notification of lapse