FR2338951A1 - Nouveaux esters-17 a d'hydroxy-17 a-progestatifs utiles comme medicaments et leurs procedes de preparation - Google Patents

Nouveaux esters-17 a d'hydroxy-17 a-progestatifs utiles comme medicaments et leurs procedes de preparation

Info

Publication number
FR2338951A1
FR2338951A1 FR7701777A FR7701777A FR2338951A1 FR 2338951 A1 FR2338951 A1 FR 2338951A1 FR 7701777 A FR7701777 A FR 7701777A FR 7701777 A FR7701777 A FR 7701777A FR 2338951 A1 FR2338951 A1 FR 2338951A1
Authority
FR
France
Prior art keywords
progestants
esters
useful
preparation methods
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7701777A
Other languages
English (en)
Other versions
FR2338951B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo AB
Original Assignee
Leo AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo AB filed Critical Leo AB
Publication of FR2338951A1 publication Critical patent/FR2338951A1/fr
Application granted granted Critical
Publication of FR2338951B1 publication Critical patent/FR2338951B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glass Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR7701777A 1976-01-22 1977-01-21 Nouveaux esters-17 a d'hydroxy-17 a-progestatifs utiles comme medicaments et leurs procedes de preparation Granted FR2338951A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2419/76A GB1558472A (en) 1976-01-22 1976-01-22 17-esters of 17- hydroxy gestogens

Publications (2)

Publication Number Publication Date
FR2338951A1 true FR2338951A1 (fr) 1977-08-19
FR2338951B1 FR2338951B1 (fr) 1979-08-24

Family

ID=9739239

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7701777A Granted FR2338951A1 (fr) 1976-01-22 1977-01-21 Nouveaux esters-17 a d'hydroxy-17 a-progestatifs utiles comme medicaments et leurs procedes de preparation

Country Status (18)

Country Link
US (1) US4177269A (fr)
JP (1) JPS52111553A (fr)
AT (1) AT360183B (fr)
AU (1) AU2142677A (fr)
BE (1) BE850668A (fr)
CA (1) CA1087168A (fr)
DE (1) DE2702509A1 (fr)
DK (1) DK25277A (fr)
ES (1) ES455133A1 (fr)
FI (1) FI770191A (fr)
FR (1) FR2338951A1 (fr)
GB (1) GB1558472A (fr)
HU (1) HU174941B (fr)
LU (1) LU76629A1 (fr)
NL (1) NL7700637A (fr)
NO (1) NO770190L (fr)
SE (1) SE7614264L (fr)
SU (1) SU797585A3 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2433537A1 (fr) * 1978-08-14 1980-03-14 Kureha Chemical Ind Co Ltd Derives d'hormones steroides antitumoraux et leur procede de preparation

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370321A (en) * 1976-09-01 1983-01-25 Mead Johnson And Company Progestational adjuvant therapy
US4261910A (en) * 1978-08-14 1981-04-14 Kureha Kagaku Kogyo Kabushiki Kaisha Process for the preparation of Chlorambucil derivatives
DE3210637A1 (de) * 1982-03-23 1983-09-29 Stiftung Deutsches Krebsforschungszentrum, 6900 Heidelberg Steroidester von n-(2-halogenethyl)-n-nitroso-carbamoylaminosaeuren und deren peptiden, sowie verfahren zu deren herstellung
SE8303031D0 (sv) * 1983-05-30 1983-05-30 Leo Ab Improved steroid esters preparation
US4615835A (en) * 1983-11-17 1986-10-07 Stiftung Deutsches Krebsforschungs Zentrum Steroid esters of N-(2-halogenethyl)-N-nitroso-carbamoylamino and acids and peptides therefore, as well as method for preparing them
CH666276A5 (de) * 1984-06-27 1988-07-15 Onkologi N Ct Ak Med V Steroidderivate der androstanreihe.
GB2176189B (en) * 1984-07-31 1988-03-02 Onkologi N Ct Ak Med V Derivatives of 11-desoxy-17a-oxicorticosterone
JPS61293993A (ja) * 1985-06-21 1986-12-24 Kureha Chem Ind Co Ltd 新規な螢光物質，その製造方法及び薬剤
JPH0621072B2 (ja) * 1986-11-12 1994-03-23 呉羽化学工業株式会社 エストラジオ−ル誘導体よりなる免疫調節剤
WO2024026102A2 (fr) * 2022-07-28 2024-02-01 The Johns Hopkins Univeristy Promédicaments pour l'administration de testostérone au système nerveux central

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2753360A (en) * 1953-12-12 1956-07-03 Schering A G Fa Esters of 17alpha-hydroxyprogesterone
US4029778A (en) * 1969-01-23 1977-06-14 Aktiebolaget Leo Cortical steroid nitrogen mustard compositions and treatment therewith

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, VOLUME 75 1971 64081H CITE ZH. OBSHCH. KHIM. 1971, 41 3 , PAGES 688-90) *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2433537A1 (fr) * 1978-08-14 1980-03-14 Kureha Chemical Ind Co Ltd Derives d'hormones steroides antitumoraux et leur procede de preparation
FR2476093A1 (fr) * 1978-08-14 1981-08-21 Kureha Chemical Ind Co Ltd Nouveaux composes 3-hydroxy ou 3-acyloxy 1,3,5(10)-estratriene-17b-oxycarbonylmethyle et leur application en therapeutique

Also Published As

Publication number Publication date
ES455133A1 (es) 1978-05-01
JPS52111553A (en) 1977-09-19
SU797585A3 (ru) 1981-01-15
SE7614264L (sv) 1977-07-23
GB1558472A (en) 1980-01-03
NL7700637A (nl) 1977-07-26
FI770191A (fr) 1977-07-23
CA1087168A (fr) 1980-10-07
BE850668A (fr) 1977-07-22
HU174941B (hu) 1980-04-28
LU76629A1 (fr) 1978-09-13
US4177269A (en) 1979-12-04
FR2338951B1 (fr) 1979-08-24
DE2702509A1 (de) 1977-07-28
ATA37877A (de) 1980-05-15
AT360183B (de) 1980-12-29
AU2142677A (en) 1978-07-27
DK25277A (da) 1977-07-23
NO770190L (no) 1977-07-25

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