FR2332016A1 - Derives n-acyles de thienamycine utiles comme antibiotiques - Google Patents

Derives n-acyles de thienamycine utiles comme antibiotiques

Info

Publication number
FR2332016A1
FR2332016A1 FR7634886A FR7634886A FR2332016A1 FR 2332016 A1 FR2332016 A1 FR 2332016A1 FR 7634886 A FR7634886 A FR 7634886A FR 7634886 A FR7634886 A FR 7634886A FR 2332016 A1 FR2332016 A1 FR 2332016A1
Authority
FR
France
Prior art keywords
thienamycin
antibiotics
acyl derivatives
derivatives useful
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7634886A
Other languages
English (en)
French (fr)
Other versions
FR2332016B1 (de
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2332016A1 publication Critical patent/FR2332016A1/fr
Application granted granted Critical
Publication of FR2332016B1 publication Critical patent/FR2332016B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR7634886A 1975-11-21 1976-11-19 Derives n-acyles de thienamycine utiles comme antibiotiques Granted FR2332016A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63429175A 1975-11-21 1975-11-21

Publications (2)

Publication Number Publication Date
FR2332016A1 true FR2332016A1 (fr) 1977-06-17
FR2332016B1 FR2332016B1 (de) 1978-11-10

Family

ID=24543192

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7634886A Granted FR2332016A1 (fr) 1975-11-21 1976-11-19 Derives n-acyles de thienamycine utiles comme antibiotiques

Country Status (8)

Country Link
JP (1) JPS5277083A (de)
CH (1) CH632509A5 (de)
DE (1) DE2652675A1 (de)
DK (1) DK523276A (de)
FR (1) FR2332016A1 (de)
GB (1) GB1570986A (de)
NL (1) NL189298C (de)
SE (1) SE427840B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2966187D1 (en) * 1978-08-23 1983-10-27 Beecham Group Plc Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them
AU6377980A (en) * 1979-10-29 1981-05-07 Beecham Group Limited 1-azabicyclo(3,2,0)hept-2-ene derivatives
EP0044142A1 (de) * 1980-07-03 1982-01-20 Beecham Group Plc Verfahren zur Herstellung von beta-Lactam Antibiotika
WO2017132321A1 (en) * 2016-01-29 2017-08-03 The Johns Hopkins University Novel inhibitors of bacterial growth

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1004670A (en) * 1963-04-23 1965-09-15 Beecham Res Lab Penicillins
GB1348985A (en) * 1970-06-16 1974-03-27 Merck & Co Inc Esters of cephalosporin compounds

Also Published As

Publication number Publication date
DE2652675C2 (de) 1990-02-01
JPS61346B2 (de) 1986-01-08
DK523276A (da) 1977-05-22
JPS5277083A (en) 1977-06-29
DE2652675A1 (de) 1977-06-02
NL189298C (nl) 1993-03-01
NL7612940A (nl) 1977-05-24
NL189298B (nl) 1992-10-01
GB1570986A (en) 1980-07-09
SE427840B (sv) 1983-05-09
SE7612960L (sv) 1977-05-22
CH632509A5 (en) 1982-10-15
FR2332016B1 (de) 1978-11-10

Similar Documents

Publication Publication Date Title
BE862299A (fr) 3-de-0-methylfortimicines utiles comme antibiotiques
BE832270A (fr) Derives de la 7-methoxycephalosporine
FR2285890A1 (fr) Derives de diazepine
BE839364A (fr) Derives de diazepine
BE847550A (fr) Nouveaux derives de la cephalosporine utiles comme antibiotiques et leurs procedes de preparation,
FR2292479A1 (fr) Derives de benzodiazepine
FR2332013A1 (fr) Derives n-acyles et carboxyles de thienamycine utiles comme antibiotiques
FR2332014A1 (fr) Derives n-alcoyles de thienamycine utiles en tant qu'antibiotiques
BE841496A (fr) Cephalosporines substituees par des groupements amine
BE825325A (fr) Derives de l'azetidine
FR2332016A1 (fr) Derives n-acyles de thienamycine utiles comme antibiotiques
BE847551A (fr) Nouveaux derives de la cephalosporine utiles comme antibiotiques et procedes de leur preparation,
BE840779A (fr) Diastereoisomeres de derives phenylamino-ethanol
FR2332012A1 (fr) Derives n-methylene substitues de thienamycine utiles comme antibiotiques
MC1347A1 (fr) Derives de pyridazopyridazine
BE825128R (fr) Derives de l'indole
FR2332015A1 (fr) Derives o-,n- et carboxyles de thienamycine utiles comme antibiotiques
FR2293207A1 (fr) Derives de 3-formylcephem
BE835802A (fr) Derives de la phenyl-pyrioylamine
FR2322122A1 (fr) Derives de tetracyclotetradecene
FR2351982A1 (fr) Derives de cephalosporine
BE847549A (fr) Nouveaux derives de la cephalosporine utiles comme antibiotiques et procedes de leur preparation,
DK458877A (da) Antibiotika
BE877139A (fr) Derives de la cephalosporine
FR2280378A1 (fr) Derives de piperidinobutyrophenone