FR2320091A2 - 4-Oxa or thia spiro (4,5) decane derivs - are CNS stimulants and psychotonics - Google Patents

4-Oxa or thia spiro (4,5) decane derivs - are CNS stimulants and psychotonics

Info

Publication number
FR2320091A2
FR2320091A2 FR7524296A FR7524296A FR2320091A2 FR 2320091 A2 FR2320091 A2 FR 2320091A2 FR 7524296 A FR7524296 A FR 7524296A FR 7524296 A FR7524296 A FR 7524296A FR 2320091 A2 FR2320091 A2 FR 2320091A2
Authority
FR
France
Prior art keywords
psychotonics
derivs
thia
oxa
decane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7524296A
Other languages
French (fr)
Other versions
FR2320091B2 (en
Inventor
Roland Yves Mauvernay
Norbert Busch
Jacques Moleyre
Jacques Simond
Andre Monteil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MAUVERNAY CENTRE EUROP RECH
Original Assignee
MAUVERNAY CENTRE EUROP RECH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MAUVERNAY CENTRE EUROP RECH filed Critical MAUVERNAY CENTRE EUROP RECH
Priority to FR7524296A priority Critical patent/FR2320091A2/en
Priority to DE2542154A priority patent/DE2542154C2/en
Priority to CA236,083A priority patent/CA1051438A/en
Priority to US05/616,357 priority patent/US4000292A/en
Priority to NLAANVRAGE7511389,A priority patent/NL183356C/en
Priority to CH1251375A priority patent/CH609689A5/xx
Priority to JP50116261A priority patent/JPS584029B2/en
Priority to ES441289A priority patent/ES441289A1/en
Priority to GB39548/75A priority patent/GB1500826A/en
Priority to MX280775U priority patent/MX3045E/en
Priority to US05/717,716 priority patent/US4086352A/en
Publication of FR2320091A2 publication Critical patent/FR2320091A2/en
Priority to US05/843,086 priority patent/USRE29902E/en
Application granted granted Critical
Publication of FR2320091B2 publication Critical patent/FR2320091B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Title cpds. of formula (I): (where A = O or S, R1,R2 independently = H, lower alkyl or aryl e.g. phenyl and X = H, halo (e.g. Cl or F) or lower alkyl, specif. where a) A = O, R1, R2 = CH3 and X = 4-F, 4-CH3, 3-CH3, 4-Cl and 3-Cl, b) A = O, R1 = CH3, R2 = H and X = 3-CH3, 3-Cl, 4-CH3, 4-F, 4-Cl and H, c) A = O, R1 = phenyl, R2 = H, and X = 3-CH3, 3-Cl or 4-Cl d) A = S, R1 = CH3, R2 = H and X=4-CH3, H, 2-CH3, 3-CH3, 3-Cl and 4-Cl) are CNS stimulants and psychotonics administered e.g. in doses of 25 mg. (I) have low toxicity cf. amphetamines.
FR7524296A 1974-09-27 1975-08-04 4-Oxa or thia spiro (4,5) decane derivs - are CNS stimulants and psychotonics Granted FR2320091A2 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR7524296A FR2320091A2 (en) 1975-08-04 1975-08-04 4-Oxa or thia spiro (4,5) decane derivs - are CNS stimulants and psychotonics
DE2542154A DE2542154C2 (en) 1974-09-27 1975-09-22 6- (3-chloro) phenoxy-3-methyl-2-oxo-1-aza-4-oxa-spiro [4,5] decane, process for its preparation and pharmaceuticals containing it
CA236,083A CA1051438A (en) 1974-09-27 1975-09-23 6-aryloxy-2-oxo-1-aza-4-oxa (or thia)-spiro 4,5 decanes
US05/616,357 US4000292A (en) 1974-09-27 1975-09-24 6-Aryloxy-2-oxo-1-aza-4-oxa (or thia)-spiro[4,5] decanes
CH1251375A CH609689A5 (en) 1974-09-27 1975-09-26
JP50116261A JPS584029B2 (en) 1974-09-27 1975-09-26 6-aryloxy-2-oxo-1-aza-4-oxa-(Matahatia)-spiro (4,5) decane
NLAANVRAGE7511389,A NL183356C (en) 1974-09-27 1975-09-26 PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION WITH STIMULATING EFFECT ON THE CENTRAL NERVOUS SYSTEM, AND METHOD FOR PREPARING THE USE OF 5-SUBSTITUTED-2-OINOPERATED-OIN-ATERO-PERIATED OIL-ATO-OXYPHYLENE OXYPHANE.
ES441289A ES441289A1 (en) 1974-09-27 1975-09-26 6-aryloxy-2-oxo-1-aza-4-oxa (or thia)-spiro(4,5)+0 decanes
GB39548/75A GB1500826A (en) 1974-09-27 1975-09-26 Spiro compounds and their use in pharmaceutical compositions
MX280775U MX3045E (en) 1974-09-27 1975-09-29 PROCEDURE FOR OBTAINING 6 - ARIL OXI - 2 - OXO - 1 - AZA - 4 - OXA (or TIA) - SPIRO [4, 5] DECANS
US05/717,716 US4086352A (en) 1974-09-27 1976-08-25 Certain 6-aryloxy-2-oxo-1-aza-4-thia-spiro[4,5]decanes
US05/843,086 USRE29902E (en) 1974-09-27 1977-10-17 6-Aryloxy-2-oxo-1-aza-4-oxo (or thia)-spiro[4,5]decanes as CNS stimulants

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7524296A FR2320091A2 (en) 1975-08-04 1975-08-04 4-Oxa or thia spiro (4,5) decane derivs - are CNS stimulants and psychotonics

Publications (2)

Publication Number Publication Date
FR2320091A2 true FR2320091A2 (en) 1977-03-04
FR2320091B2 FR2320091B2 (en) 1978-08-25

Family

ID=9158735

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7524296A Granted FR2320091A2 (en) 1974-09-27 1975-08-04 4-Oxa or thia spiro (4,5) decane derivs - are CNS stimulants and psychotonics

Country Status (1)

Country Link
FR (1) FR2320091A2 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Also Published As

Publication number Publication date
FR2320091B2 (en) 1978-08-25

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