FR2286642A2 - 2-(Naphthyridin-2-yl)-isoindolin-1-one derivs - contg. 3-(piperazin-1-yl-carbonyloxy) gp., used as tranquillisers and antidepressants - Google Patents
2-(Naphthyridin-2-yl)-isoindolin-1-one derivs - contg. 3-(piperazin-1-yl-carbonyloxy) gp., used as tranquillisers and antidepressantsInfo
- Publication number
- FR2286642A2 FR2286642A2 FR7408728A FR7408728A FR2286642A2 FR 2286642 A2 FR2286642 A2 FR 2286642A2 FR 7408728 A FR7408728 A FR 7408728A FR 7408728 A FR7408728 A FR 7408728A FR 2286642 A2 FR2286642 A2 FR 2286642A2
- Authority
- FR
- France
- Prior art keywords
- tranquillisers
- isoindolin
- derivs
- naphthyridin
- carbonyloxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Cpds. of formula (I) and their acid addition salts are new. (where 1 gp. X is N and the other 3 are CY; each Y is H, halogen, 1-4C alk(ox)yl, CN or NO2; A and A1 are CH or N, such that when A is CH, A1 is CH or N, but when A is N, A1 is N; Z is each H, halogen, 1-4C alk(ox)yl or NO2; either (i) n is zero and R is H, 1-4C (hydroxy)alkyl, 2-4C alkenyl, 2-4C alkynyl or phenyl, or (ii) n is 1 and R is 1-4C (hydroxy)alkyl or phenyl). Prepn. is e.g. by reacting the corresp. cpd. where the piperazinyl gp. is replaced by (substd.) phenyl with the corresp. 1-unsubstd. piperazine.
Priority Applications (39)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7408728A FR2286642A2 (en) | 1974-03-14 | 1974-03-14 | 2-(Naphthyridin-2-yl)-isoindolin-1-one derivs - contg. 3-(piperazin-1-yl-carbonyloxy) gp., used as tranquillisers and antidepressants |
OA55189A OA04700A (en) | 1973-05-15 | 1974-04-29 | New derivatives of naphthyridine and their preparation process. |
PH15794A PH11400A (en) | 1973-05-15 | 1974-04-30 | Naphthyridine derivatives and pharmaceutical composition thereof |
NL7406194A NL7406194A (en) | 1973-05-15 | 1974-05-08 | |
IL44815A IL44815A (en) | 1973-05-15 | 1974-05-13 | 3-(piperazin-1-yl) carbonyloxy (naphthyridin-2-yl) isoindolinones pyrrolo (3,4-b) pyrazines and pyrrolo (3,4-b) pyridines processes for the preparation thereof and pharmaceutical compositions containing the same |
IE1012/74A IE39263B1 (en) | 1973-05-15 | 1974-05-13 | Naphthyridine derivatives |
JP49052378A JPS5758345B2 (en) | 1973-05-15 | 1974-05-13 | |
GB2108174A GB1417935A (en) | 1973-05-15 | 1974-05-13 | Naphthyridine derivatives |
AU68880/74A AU478373B2 (en) | 1973-05-15 | 1974-05-13 | Naphthyridine derivatives |
HURO780A HU169609B (en) | 1973-05-15 | 1974-05-13 | |
LU70071A LU70071A1 (en) | 1973-05-15 | 1974-05-14 | |
SE7406452A SE410857B (en) | 1973-05-15 | 1974-05-14 | PROCEDURE FOR THE PREPARATION OF NEW NAFTYRIDINE DERIVATIVES |
MX561874U MX4617E (en) | 1973-05-15 | 1974-05-14 | PROCEDURE FOR THE PREPARATION OF NAFTIRIDINE DERIVATIVES |
CA199,810A CA1012971A (en) | 1973-05-15 | 1974-05-14 | Naphtyridine derivatives, method of manufacture and compositions that contain them |
CH659574A CH592662A5 (en) | 1973-05-15 | 1974-05-14 | |
DK263374AA DK136819B (en) | 1973-05-15 | 1974-05-14 | Analogous process for the preparation of derivatives of naphthyridine or acid addition salts thereof. |
SU7402026597A SU583757A3 (en) | 1973-05-15 | 1974-05-14 | Method of preparing naphthyridine derivatives or salts thereof |
CH53477A CH592663A5 (en) | 1973-05-15 | 1974-05-14 | |
ES426335A ES426335A1 (en) | 1973-05-15 | 1974-05-14 | Naphthyridine derivatives |
DD178499A DD111078A5 (en) | 1973-05-15 | 1974-05-14 | |
ES426337A ES426337A1 (en) | 1974-03-14 | 1974-05-14 | Procedure for preparing naftiridine derivatives. (Machine-translation by Google Translate, not legally binding) |
ES426336A ES426336A1 (en) | 1973-05-15 | 1974-05-14 | Naphthyridine derivatives |
NO741744A NO140012C (en) | 1973-05-15 | 1974-05-14 | ANALOGICAL PROCEDURE FOR THE PREPARATION OF NEW THERAPEUTICALLY ACTIVE DERIVATIVES OF NAFTYRIDINE |
FI1498/74A FI55659C (en) | 1973-05-15 | 1974-05-15 | FORM OF THERAPEUTIC ACTIVATION OF THERAPEUTIC ACTIVITIES 3- (4-SUBSTITUTES-PIPERAZIN-1-YLCARBONYLOXY) -2- (1,8-NAPHTHYRIDIN-2-YL) ISOINDOLIN-1-ONER |
AR253755A AR209421A1 (en) | 1973-05-15 | 1974-05-15 | PROCEDURE FOR THE PREPARATION OF ISOINDOLINONE-1 AND ITS MONO AND DIAZOTATED (NAPHTHYRIDINE-1.8 IL-2) -6 (PIPERAZINIL) -6 (PIPERAZINIL-1-CARBONYLOXY) RIVATES -1-CARBONYLOXY) -7-OXO 5 PYRROLPYRIDINES AND (NAPHTHYRIDINE1,8 IL-2), 6 (PIPERAZINYL-1 CARBONYLOXY) -7 OXO-5 PYRROLPYRIDINES |
PL1974171103A PL90061B1 (en) | 1973-05-15 | 1974-05-15 | Naphthydridine[au6888074a] |
AT400874A AT336030B (en) | 1973-05-15 | 1974-05-15 | PROCESS FOR THE PREPARATION OF NEW NAPHTHYRIDE DERIVATIVES AND THEIR ACID ADDITIONAL SALTS |
CS743472A CS191881B2 (en) | 1973-05-15 | 1974-05-15 | Method of producing novel derivatives of naphtyridine |
YU01336/74A YU133674A (en) | 1973-05-15 | 1974-05-15 | Process for obtaining new naphthiridine derivatives |
DE2423650A DE2423650A1 (en) | 1973-05-15 | 1974-05-15 | NEW NAPHTYRIDE DERIVATIVES, THEIR PRODUCTION AND COMPOSITIONS THEREOF |
AR257458A AR210851A1 (en) | 1973-05-15 | 1975-01-29 | PROCEDURE TO PREPARE NEW DERIVATIVES OF (NAPHTHYRIDINE-1,8 IL-2) 1 (PIPERAZINIL) -1CARBONYLOXY-3) -2 OXO-5 PYRROLINE |
SU752112823A SU589916A3 (en) | 1973-05-15 | 1975-03-18 | Method of preparing naphthyridine derivatives or salts thereof |
SU752114917A SU629877A3 (en) | 1974-03-14 | 1975-03-19 | Method of obtaining naphthyridine derivatives or salts thereof |
US05/623,359 US4016274A (en) | 1973-05-15 | 1975-10-17 | Naphthyridine derivatives |
US05/623,358 US4038391A (en) | 1973-05-15 | 1975-10-17 | 6-(1,8-Naphthyridin-2-yl)-5-piperazino carbonyloxy-7-oxo-6,7-dihydro-5H-pyrrolo-[3,4-b]pyrazines and related pyridines |
AT86676A AT336031B (en) | 1973-05-15 | 1976-02-09 | PROCESS FOR THE PREPARATION OF NEW NAPHTHYRIDE DERIVATIVES AND THEIR ACID ADDITIONAL SALTS |
CS766364A CS191887B2 (en) | 1973-05-15 | 1976-10-01 | Method of producing novel derivatives of naphtyridine |
YU02877/81A YU287781A (en) | 1973-05-15 | 1981-12-08 | Process for obtaining new naphthiridine derivatives |
YU287681A YU287681A (en) | 1974-03-14 | 1981-12-08 | Process for obtaining new naphthiridine derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7408728A FR2286642A2 (en) | 1974-03-14 | 1974-03-14 | 2-(Naphthyridin-2-yl)-isoindolin-1-one derivs - contg. 3-(piperazin-1-yl-carbonyloxy) gp., used as tranquillisers and antidepressants |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2286642A2 true FR2286642A2 (en) | 1976-04-30 |
FR2286642B2 FR2286642B2 (en) | 1979-07-20 |
Family
ID=9136325
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7408728A Granted FR2286642A2 (en) | 1973-05-15 | 1974-03-14 | 2-(Naphthyridin-2-yl)-isoindolin-1-one derivs - contg. 3-(piperazin-1-yl-carbonyloxy) gp., used as tranquillisers and antidepressants |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2286642A2 (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2301069A1 (en) * | 1972-01-10 | 1973-07-19 | Rhone Poulenc Sa | NEW ISOINDOLINE DERIVATIVES, THEIR MANUFACTURING AND THE MEDICAL COMPOSITIONS THAT CONTAIN THEM |
-
1974
- 1974-03-14 FR FR7408728A patent/FR2286642A2/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2301069A1 (en) * | 1972-01-10 | 1973-07-19 | Rhone Poulenc Sa | NEW ISOINDOLINE DERIVATIVES, THEIR MANUFACTURING AND THE MEDICAL COMPOSITIONS THAT CONTAIN THEM |
Also Published As
Publication number | Publication date |
---|---|
FR2286642B2 (en) | 1979-07-20 |
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