FR2279758A1 - Procede et composes intermediaires pour la synthese de la betamethasone - Google Patents

Procede et composes intermediaires pour la synthese de la betamethasone

Info

Publication number: FR2279758A1
Authority: FR; France
Prior art keywords: betamethasone; synthesis; intermediate compounds; compounds
Prior art date: 1973-02-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

FR7504889A

Other languages

English (en)

Other versions

FR2279758B1 (fr

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Omni Research Inc

Original Assignee

Omni Research Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-02-21

Filing date

1975-02-17

Publication date

1976-02-20

1975-02-17 Application filed by Omni Research Inc filed Critical Omni Research Inc

1976-02-20 Publication of FR2279758A1 publication Critical patent/FR2279758A1/fr

1978-02-03 Application granted granted Critical

1978-02-03 Publication of FR2279758B1 publication Critical patent/FR2279758B1/fr

Status Granted legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)

FR7504889A 1973-02-21 1975-02-17 Procede et composes intermediaires pour la synthese de la betamethasone Granted FR2279758A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US334358A US3876633A (en)	1973-02-21	1973-02-21	Processes and intermediates for 16-substituted corticoid synthesis

Publications (2)

Publication Number	Publication Date
FR2279758A1 true FR2279758A1 (fr)	1976-02-20
FR2279758B1 FR2279758B1 (fr)	1978-02-03

Family

ID=23306856

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
FR7405728A Withdrawn FR2279761A1 (fr)	1973-02-21	1974-02-20	Steroides intermediaires pour la synthese de corticoides substitues en position 16
FR7504890A Granted FR2279759A1 (fr)	1973-02-21	1975-02-17	Procede et composes intermediaires pour la synthese de la dermatose
FR7504889A Granted FR2279758A1 (fr)	1973-02-21	1975-02-17	Procede et composes intermediaires pour la synthese de la betamethasone
FR7533075A Granted FR2289521A1 (fr)	1973-02-21	1975-10-29	Steroides intermediaires pour la synthese de la dexamethasone

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
FR7405728A Withdrawn FR2279761A1 (fr)	1973-02-21	1974-02-20	Steroides intermediaires pour la synthese de corticoides substitues en position 16
FR7504890A Granted FR2279759A1 (fr)	1973-02-21	1975-02-17	Procede et composes intermediaires pour la synthese de la dermatose

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
FR7533075A Granted FR2289521A1 (fr)	1973-02-21	1975-10-29	Steroides intermediaires pour la synthese de la dexamethasone

Country Status (13)

Country	Link
US (1)	US3876633A (fr)
JP (1)	JPS5111754A (fr)
BE (1)	BE811325A (fr)
BR (1)	BR7401222D0 (fr)
CA (1)	CA1031767A (fr)
DE (1)	DE2407967A1 (fr)
ES (1)	ES423481A1 (fr)
FR (4)	FR2279761A1 (fr)
GB (2)	GB1462685A (fr)
IL (1)	IL44234A (fr)
IN (1)	IN139463B (fr)
NL (1)	NL7402331A (fr)
ZA (1)	ZA741133B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1505701A (en) *	1975-06-14	1978-03-30	Pierrel Spa	2-chloro-6beta-fluoropregnanes
NL7607283A (nl) *	1975-07-23	1977-01-25	Merck & Co Inc	Werkwijze voor het bereiden van nieuwe pregnaansteroiden.
US4189430A (en) *	1978-07-31	1980-02-19	The Upjohn Company	Epoxide process
US4990612A (en) *	1984-06-11	1991-02-05	The Upjohn Company	16α-methylation process
US4704455A (en) *	1984-06-11	1987-11-03	The Upjohn Company	16α-methylatedΔ17(20)-corticoids
JPS611699A (ja) *	1984-06-11	1986-01-07	ジ　アツプジヨン　カンパニー	１６α‐メチル化法
PT78973A (en) *	1984-07-25	1984-08-01	Joao Emerico Villax	New preparation process of the 9alpha-fluoro 17,21-acylates or hidroxilades in 17 and 21 chloro-corticosteroid
FR2692266B1 (fr) *	1992-06-11	1994-08-05	Roussel Uclaf	Nouveau procede de preparation de sterouides 16 alpha-methyles.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3053865A (en) *	1958-03-19	1962-09-11	Merck & Co Inc	Novel 16-alkyl and 16-alkylene steroids and processes
US3072686A (en) *	1958-10-10	1963-01-08	Ciba Geigy Corp	16alpha-alkyl-pregnane compounds and process for their manufacture
US3030389A (en) *	1961-01-23	1962-04-17	Julian Lab Inc	Processes for the preparation of 16-alkylpregnenes
US3120517A (en) *	1961-06-06	1964-02-04	American Cyanamid Co	Method of preparing allopregnenes and products resulting therefrom
CH529119A (de) *	1968-10-02	1972-10-15	Schering Ag	Verfahren zur Herstellung von 17a-Acyloxy-20-keto-steroiden

1973
- 1973-02-21 US US334358A patent/US3876633A/en not_active Expired - Lifetime
1974
- 1974-02-13 GB GB650274A patent/GB1462685A/en not_active Expired
- 1974-02-13 GB GB5327875A patent/GB1462686A/en not_active Expired
- 1974-02-19 DE DE19742407967 patent/DE2407967A1/de active Pending
- 1974-02-19 IL IL44234A patent/IL44234A/xx unknown
- 1974-02-20 FR FR7405728A patent/FR2279761A1/fr not_active Withdrawn
- 1974-02-20 BE BE141174A patent/BE811325A/fr unknown
- 1974-02-20 BR BR741222A patent/BR7401222D0/pt unknown
- 1974-02-20 NL NL7402331A patent/NL7402331A/xx unknown
- 1974-02-21 ZA ZA00741133A patent/ZA741133B/xx unknown
- 1974-02-21 JP JP49020976A patent/JPS5111754A/ja active Pending
- 1974-02-21 ES ES423481A patent/ES423481A1/es not_active Expired
- 1974-02-21 CA CA193,178A patent/CA1031767A/fr not_active Expired
- 1974-02-22 IN IN380/CAL/74A patent/IN139463B/en unknown
1975
- 1975-02-17 FR FR7504890A patent/FR2279759A1/fr active Granted
- 1975-02-17 FR FR7504889A patent/FR2279758A1/fr active Granted
- 1975-10-29 FR FR7533075A patent/FR2289521A1/fr active Granted

Also Published As

Publication number	Publication date
FR2279758B1 (fr)	1978-02-03
FR2289521A1 (fr)	1976-05-28
US3876633A (en)	1975-04-08
IN139463B (fr)	1976-06-19
FR2279761A1 (fr)	1976-02-20
JPS5111754A (en)	1976-01-30
ES423481A1 (es)	1976-06-01
AU6584774A (en)	1975-08-21
NL7402331A (fr)	1974-08-23
ZA741133B (en)	1975-04-30
IL44234A (en)	1978-07-31
BR7401222D0 (pt)	1974-11-05
DE2407967A1 (de)	1974-08-29
GB1462686A (en)	1977-01-26
FR2279759A1 (fr)	1976-02-20
CA1031767A (fr)	1978-05-23
BE811325A (fr)	1974-06-17
GB1462685A (en)	1977-01-26
IL44234A0 (en)	1974-05-16
FR2279759B1 (fr)	1978-02-03
FR2289521B1 (fr)	1978-04-07

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Legal Events

Date	Code	Title	Description
1979-12-21	ST	Notification of lapse