FR2270887A1 - Prepn of lecithins and glycol-lecithins - by reaction of trimethylamine with 2-substd-2-oxo-1,3,2-dioxaphospholans - Google Patents

Prepn of lecithins and glycol-lecithins - by reaction of trimethylamine with 2-substd-2-oxo-1,3,2-dioxaphospholans

Info

Publication number
FR2270887A1
FR2270887A1 FR7417117A FR7417117A FR2270887A1 FR 2270887 A1 FR2270887 A1 FR 2270887A1 FR 7417117 A FR7417117 A FR 7417117A FR 7417117 A FR7417117 A FR 7417117A FR 2270887 A1 FR2270887 A1 FR 2270887A1
Authority
FR
France
Prior art keywords
lecithins
oxo
reaction
dioxaphospholans
substd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7417117A
Other languages
French (fr)
Other versions
FR2270887B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHABRIER DE LASSAUNIERE PIERRE FR
Original Assignee
CHABRIER DE LASSAUNIERE PIERRE FR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHABRIER DE LASSAUNIERE PIERRE FR filed Critical CHABRIER DE LASSAUNIERE PIERRE FR
Priority to FR7417117A priority Critical patent/FR2270887A1/en
Publication of FR2270887A1 publication Critical patent/FR2270887A1/en
Application granted granted Critical
Publication of FR2270887B1 publication Critical patent/FR2270887B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
    • C07F9/65742—Esters of oxyacids of phosphorus non-condensed with carbocyclic rings or heterocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)

Abstract

Phosphorylcholines of formulae (a), (b) and (c) are prepd. by reaction of NM3, with phospholons of formulae (a'), (b') or (c') (where R and R' are opt. unsatd. alkyl. n is 2 or 3). The phospholons (a'), (b') and (c') are prepd. by condensation in an inert solvent in presence of an acid-binding agent of 2-chloro-2-oxo-1,3,2-dioxaphospholan on cpds. (a"), (b"), or (c").
FR7417117A 1974-05-16 1974-05-16 Prepn of lecithins and glycol-lecithins - by reaction of trimethylamine with 2-substd-2-oxo-1,3,2-dioxaphospholans Granted FR2270887A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7417117A FR2270887A1 (en) 1974-05-16 1974-05-16 Prepn of lecithins and glycol-lecithins - by reaction of trimethylamine with 2-substd-2-oxo-1,3,2-dioxaphospholans

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7417117A FR2270887A1 (en) 1974-05-16 1974-05-16 Prepn of lecithins and glycol-lecithins - by reaction of trimethylamine with 2-substd-2-oxo-1,3,2-dioxaphospholans

Publications (2)

Publication Number Publication Date
FR2270887A1 true FR2270887A1 (en) 1975-12-12
FR2270887B1 FR2270887B1 (en) 1978-02-03

Family

ID=9138967

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7417117A Granted FR2270887A1 (en) 1974-05-16 1974-05-16 Prepn of lecithins and glycol-lecithins - by reaction of trimethylamine with 2-substd-2-oxo-1,3,2-dioxaphospholans

Country Status (1)

Country Link
FR (1) FR2270887A1 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2752125A1 (en) * 1977-11-22 1979-05-23 Max Planck Gesellschaft NEW ORGANIC PHOSPHORUS RING COMPOUNDS, THEIR PRODUCTION AND USE
EP0011745A1 (en) * 1978-11-21 1980-06-11 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Colloidal aqueous formulation for pharmacy and its preparation
FR2541283A1 (en) * 1983-02-21 1984-08-24 Sanofi Sa Process for the preparation of (2-acyloxy-1-(alkylthio)propyl)phosphorylcholine
EP0198388A2 (en) * 1985-04-08 1986-10-22 Research Corporation Enterally effective biologically active peptide or protein composition, method for the production thereof, and a pharmaceutical composition containing same
WO1997014702A1 (en) * 1995-10-16 1997-04-24 Biocompatibles Limited Oxidation of phosphorus compounds
WO1997014703A1 (en) * 1995-10-16 1997-04-24 Biocompatibles Limited Synthesis of polymerisable phosphodiesters
US5741923A (en) * 1993-11-23 1998-04-21 Biocompatibles Limited Ethylenically unsaturated compounds
WO2013033554A1 (en) 2011-09-01 2013-03-07 Vertellus Specialties Inc. Biocompatible material

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2752125A1 (en) * 1977-11-22 1979-05-23 Max Planck Gesellschaft NEW ORGANIC PHOSPHORUS RING COMPOUNDS, THEIR PRODUCTION AND USE
EP0011745A1 (en) * 1978-11-21 1980-06-11 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Colloidal aqueous formulation for pharmacy and its preparation
FR2541283A1 (en) * 1983-02-21 1984-08-24 Sanofi Sa Process for the preparation of (2-acyloxy-1-(alkylthio)propyl)phosphorylcholine
EP0198388A2 (en) * 1985-04-08 1986-10-22 Research Corporation Enterally effective biologically active peptide or protein composition, method for the production thereof, and a pharmaceutical composition containing same
EP0198388A3 (en) * 1985-04-08 1988-02-03 Research Corporation Enterally effective biologically active peptide or protein composition, method for the production thereof, and a pharmaceutical composition containing same
US5741923A (en) * 1993-11-23 1998-04-21 Biocompatibles Limited Ethylenically unsaturated compounds
WO1997014702A1 (en) * 1995-10-16 1997-04-24 Biocompatibles Limited Oxidation of phosphorus compounds
WO1997014703A1 (en) * 1995-10-16 1997-04-24 Biocompatibles Limited Synthesis of polymerisable phosphodiesters
WO2013033554A1 (en) 2011-09-01 2013-03-07 Vertellus Specialties Inc. Biocompatible material

Also Published As

Publication number Publication date
FR2270887B1 (en) 1978-02-03

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Legal Events

Date Code Title Description
ST Notification of lapse