FR2255883A1 - Clofibric acid-vitamin B6 compsns. - with synergistic hypocholesterolaemic and normolipaemic activity - Google Patents
Clofibric acid-vitamin B6 compsns. - with synergistic hypocholesterolaemic and normolipaemic activityInfo
- Publication number
- FR2255883A1 FR2255883A1 FR7346740A FR7346740A FR2255883A1 FR 2255883 A1 FR2255883 A1 FR 2255883A1 FR 7346740 A FR7346740 A FR 7346740A FR 7346740 A FR7346740 A FR 7346740A FR 2255883 A1 FR2255883 A1 FR 2255883A1
- Authority
- FR
- France
- Prior art keywords
- activity
- normolipaemic
- hypocholesterolaemic
- compsns
- vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
Abstract
Hypocholesterolaemic and normolipaemic compsns. contain as active components p-chlorophenoxyisobutyric acid (clofibric acid) and a cpd. with vitamin B6 activity in a w/w ratio of 0.1 to 20:1, pref. 1:10 (salts and esters of clofibric acid may be used). Suitable cpds. with B6 activity are pyridoxine, pyridoxamine and pyridoxal.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7346740A FR2255883A1 (en) | 1973-12-28 | 1973-12-28 | Clofibric acid-vitamin B6 compsns. - with synergistic hypocholesterolaemic and normolipaemic activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7346740A FR2255883A1 (en) | 1973-12-28 | 1973-12-28 | Clofibric acid-vitamin B6 compsns. - with synergistic hypocholesterolaemic and normolipaemic activity |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2255883A1 true FR2255883A1 (en) | 1975-07-25 |
FR2255883B1 FR2255883B1 (en) | 1977-07-08 |
Family
ID=9129850
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7346740A Granted FR2255883A1 (en) | 1973-12-28 | 1973-12-28 | Clofibric acid-vitamin B6 compsns. - with synergistic hypocholesterolaemic and normolipaemic activity |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2255883A1 (en) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5288716A (en) * | 1987-02-18 | 1994-02-22 | Ulrich Speck | Use of pyridoxine derivatives in the prevention and treatment of hyperlipidaemia and atherosclerosis |
US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
US6339085B1 (en) | 1999-03-08 | 2002-01-15 | The University Of Manitoba | Therapeutics for cardiovascular and related diseases |
US6417204B1 (en) | 2000-07-07 | 2002-07-09 | Medicure International Inc. | Pyridoxine AMD pyridoxal analogues: cardiovascular therapeutics |
US6489345B1 (en) | 1999-07-13 | 2002-12-03 | Medicure, Inc. | Treatment of diabetes and related pathologies |
US6548519B1 (en) | 2001-07-06 | 2003-04-15 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: novel uses |
US6586414B2 (en) | 2000-03-28 | 2003-07-01 | Medicure International Inc. | Treatment of cerebrovascular disease |
US6605612B2 (en) | 2000-02-29 | 2003-08-12 | Medicure International Inc. | Cardioprotective phosohonates and malonates |
US6677356B1 (en) | 1999-08-24 | 2004-01-13 | Medicure International Inc. | Treatment of cardiovascular and related pathologies |
US6897228B2 (en) | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006050598A1 (en) | 2004-10-28 | 2006-05-18 | Medicure International Inc. | Dual antiplatelet/anticoagulant pyridoxine analogs |
-
1973
- 1973-12-28 FR FR7346740A patent/FR2255883A1/en active Granted
Cited By (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5288716A (en) * | 1987-02-18 | 1994-02-22 | Ulrich Speck | Use of pyridoxine derivatives in the prevention and treatment of hyperlipidaemia and atherosclerosis |
US6066659A (en) * | 1987-02-18 | 2000-05-23 | Steigerwald Arzneimittelwerk Gmbh | Use of pyridoxine derivatives in the prevention and treatment of hyperlipidaemia and atherosclerosis |
US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
US7230009B2 (en) | 1999-03-08 | 2007-06-12 | Medicure, Inc. | Pyridoxal analogues and methods of treatment |
US6339085B1 (en) | 1999-03-08 | 2002-01-15 | The University Of Manitoba | Therapeutics for cardiovascular and related diseases |
US6890943B2 (en) | 1999-03-08 | 2005-05-10 | Medicure Inc. | Pyridoxal analogues and methods of treatment |
US6489345B1 (en) | 1999-07-13 | 2002-12-03 | Medicure, Inc. | Treatment of diabetes and related pathologies |
US6677356B1 (en) | 1999-08-24 | 2004-01-13 | Medicure International Inc. | Treatment of cardiovascular and related pathologies |
US7125889B2 (en) | 1999-08-24 | 2006-10-24 | Medicure International Inc. | Treating of cardiovascular and related pathologies |
US7144892B2 (en) | 1999-08-24 | 2006-12-05 | Merrill Lynch Capital Canada Inc. | Treatment of cardiovascular and related pathologies |
US7148233B2 (en) | 1999-08-24 | 2006-12-12 | Merrill Lynch Capital Canada Inc. | Treatment of cardiovascular and related pathologies |
US7132430B2 (en) | 1999-08-24 | 2006-11-07 | Medicure International Inc. | Treatment of cardiovascular and related pathologies |
US7115626B2 (en) | 1999-08-24 | 2006-10-03 | Medicure International Inc. | Treatment of cardiovascular and related pathologies |
US7115625B2 (en) | 1999-08-24 | 2006-10-03 | Medicure International Inc. | Treatment of cardiovascular and related pathologies |
US6605612B2 (en) | 2000-02-29 | 2003-08-12 | Medicure International Inc. | Cardioprotective phosohonates and malonates |
US6667315B2 (en) | 2000-02-29 | 2003-12-23 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
US6780997B2 (en) | 2000-02-29 | 2004-08-24 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
US6867215B2 (en) | 2000-02-29 | 2005-03-15 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
US7105673B2 (en) | 2000-02-29 | 2006-09-12 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
US6861439B2 (en) | 2000-03-28 | 2005-03-01 | Medicure International, Inc. | Treatment of cerebrovascular disease |
US6586414B2 (en) | 2000-03-28 | 2003-07-01 | Medicure International Inc. | Treatment of cerebrovascular disease |
US6897228B2 (en) | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
US6417204B1 (en) | 2000-07-07 | 2002-07-09 | Medicure International Inc. | Pyridoxine AMD pyridoxal analogues: cardiovascular therapeutics |
US6548519B1 (en) | 2001-07-06 | 2003-04-15 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: novel uses |
Also Published As
Publication number | Publication date |
---|---|
FR2255883B1 (en) | 1977-07-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |