FR2247219A1 - Substd cyclopentenyl derivs as prostaglandin analogues - having longer and more specific action than natural cpds - Google Patents
Substd cyclopentenyl derivs as prostaglandin analogues - having longer and more specific action than natural cpdsInfo
- Publication number
- FR2247219A1 FR2247219A1 FR7434340A FR7434340A FR2247219A1 FR 2247219 A1 FR2247219 A1 FR 2247219A1 FR 7434340 A FR7434340 A FR 7434340A FR 7434340 A FR7434340 A FR 7434340A FR 2247219 A1 FR2247219 A1 FR 2247219A1
- Authority
- FR
- France
- Prior art keywords
- substd
- alkyl
- natural
- cpds
- specific action
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 229940006138 antiglaucoma drug and miotics prostaglandin analogues Drugs 0.000 title abstract 2
- 125000002433 cyclopentenyl group Chemical group C1(=CCCC1)* 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000005073 adamantyl group Chemical group C12(CC3CC(CC(C1)C3)C2)* 0.000 abstract 1
- 125000002723 alicyclic group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- -1 esters amides Chemical class 0.000 abstract 1
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000005359 phenoxyalkyl group Chemical group 0.000 abstract 1
- 125000004368 propenyl group Chemical group C(=CC)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL7314038A NL7314038A (nl) | 1973-10-12 | 1973-10-12 | Nieuwe prostaglandine analoga. |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2247219A1 true FR2247219A1 (en) | 1975-05-09 |
Family
ID=19819808
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7434340A Withdrawn FR2247219A1 (en) | 1973-10-12 | 1974-10-11 | Substd cyclopentenyl derivs as prostaglandin analogues - having longer and more specific action than natural cpds |
Country Status (6)
Country | Link |
---|---|
JP (1) | JPS5077344A (fr) |
BE (1) | BE820988A (fr) |
DE (1) | DE2448392A1 (fr) |
FR (1) | FR2247219A1 (fr) |
NL (1) | NL7314038A (fr) |
SE (1) | SE7412813L (fr) |
-
1973
- 1973-10-12 NL NL7314038A patent/NL7314038A/xx unknown
-
1974
- 1974-10-10 DE DE19742448392 patent/DE2448392A1/de active Pending
- 1974-10-11 JP JP49117008A patent/JPS5077344A/ja active Pending
- 1974-10-11 SE SE7412813A patent/SE7412813L/xx not_active Application Discontinuation
- 1974-10-11 BE BE149460A patent/BE820988A/fr unknown
- 1974-10-11 FR FR7434340A patent/FR2247219A1/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JPS5077344A (fr) | 1975-06-24 |
BE820988A (fr) | 1975-04-11 |
DE2448392A1 (de) | 1975-04-17 |
NL7314038A (nl) | 1975-04-15 |
SE7412813L (fr) | 1975-04-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PH19447A (en) | New composition of matter and their use for relaxation of uterus | |
EP0379147A3 (fr) | Gel élastique extrudable utilisable comme support pour des substances thérapeutiques | |
JPS55153715A (en) | Prolonged granule of theophylline | |
GB1352092A (en) | Dioxolane derivatives and their use as flavouring agents | |
ES452226A1 (es) | Procedimiento para la preparacion de delta15-esteroides. | |
ATE25966T1 (de) | Aminocyclohexanol-derivate mit expektoranter wirkung, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
FR2247219A1 (en) | Substd cyclopentenyl derivs as prostaglandin analogues - having longer and more specific action than natural cpds | |
GB1297398A (fr) | ||
GB1369249A (en) | Amines the preparation thereof and their use in pharmaceutical compositions | |
ES343957A1 (es) | Procedimiento de obtencion de polisacaridos sulfatados an- tilipemicos activos por via oral. | |
IL45269A (en) | N-(3-alkylphenyl)-n' n'-dimethyl-ureas their preparation and their use as selective herbicides | |
JPS5218832A (en) | Method of making cosmetic preparation | |
ES2043608T3 (es) | Procedimiento para la preparacion de composiciones farmaceuticas con acetil-l-carnitina para el tratamiento terapeutico de condicones de shock. | |
ES8609207A1 (es) | Procedimiento para la preparacion de derivados de feniletilamina. | |
ES443574A1 (es) | Procedimiento para la obtencion de derivados de ciclopenta- no. | |
IE39977L (en) | N- (4-quinolyl)-anthranilic acid derivatives. | |
BE791772A (fr) | Derives d'acides phenoxy-acetiques, leur preparation et leur application en therapeutique | |
ES421570A1 (es) | Un procedimiento para la preparacion de nuevos derivados de cianopregnenona. | |
IL45655A0 (en) | New n'-(aminoacylaminophenyl)-acetamidenes and salts thereof,their production and their medicinal use | |
USD230793S (en) | Chair | |
JPS56138112A (en) | Suppository containing ascorbic acid or sodium ascorbate | |
USD227427S (en) | Chair | |
JPS5592315A (en) | Remedy for cataract | |
USD227628S (en) | Combined cabinet and table | |
MARKARIAN et al. | Etiology and prophylaxis of vestibular disorders in flying personnel |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Withdrawal of published application |