FR2244541A1 - Amino acid salts of quinine alkaloids - as phospho-lipase inhibitors and anti-acne agents - Google Patents

Amino acid salts of quinine alkaloids - as phospho-lipase inhibitors and anti-acne agents

Info

Publication number
FR2244541A1
FR2244541A1 FR7328418A FR7328418A FR2244541A1 FR 2244541 A1 FR2244541 A1 FR 2244541A1 FR 7328418 A FR7328418 A FR 7328418A FR 7328418 A FR7328418 A FR 7328418A FR 2244541 A1 FR2244541 A1 FR 2244541A1
Authority
FR
France
Prior art keywords
phospho
amino acid
acid salts
lipase inhibitors
acne agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7328418A
Other languages
French (fr)
Other versions
FR2244541B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre SA
Original Assignee
Pierre Fabre SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre SA filed Critical Pierre Fabre SA
Priority to FR7328418A priority Critical patent/FR2244541A1/en
Publication of FR2244541A1 publication Critical patent/FR2244541A1/en
Application granted granted Critical
Publication of FR2244541B1 publication Critical patent/FR2244541B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/008—Preparations for oily skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/006—Antidandruff preparations

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel quinone alkaloid salts of formula (I):- (where R is H, or alkoxy and R1COOH is an org acid esp. glutamic, aspartic, pyrrolidone carboxylic, acylglutamic or acylaspartic, acids, N-acetylcysteine, N-acetyl methionine, N-acetylcystine and N-acyl-cysteine- and methionine), are inhibitors of phospholipases and agents for treating acne.
FR7328418A 1973-08-01 1973-08-01 Amino acid salts of quinine alkaloids - as phospho-lipase inhibitors and anti-acne agents Granted FR2244541A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7328418A FR2244541A1 (en) 1973-08-01 1973-08-01 Amino acid salts of quinine alkaloids - as phospho-lipase inhibitors and anti-acne agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7328418A FR2244541A1 (en) 1973-08-01 1973-08-01 Amino acid salts of quinine alkaloids - as phospho-lipase inhibitors and anti-acne agents

Publications (2)

Publication Number Publication Date
FR2244541A1 true FR2244541A1 (en) 1975-04-18
FR2244541B1 FR2244541B1 (en) 1977-09-02

Family

ID=9123542

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7328418A Granted FR2244541A1 (en) 1973-08-01 1973-08-01 Amino acid salts of quinine alkaloids - as phospho-lipase inhibitors and anti-acne agents

Country Status (1)

Country Link
FR (1) FR2244541A1 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2511676A1 (en) * 1981-08-18 1983-02-25 Mollet Marc QUININE PANTOTHENATES, PROCESSES FOR THEIR PREPARATION AND COSMETOLOGICAL PRODUCTS COMPRISING THE SAME
US5296500A (en) * 1991-08-30 1994-03-22 The Procter & Gamble Company Use of N-acetyl-cysteine and derivatives for regulating skin wrinkles and/or skin atrophy
US5451405A (en) * 1994-04-25 1995-09-19 Chesebrough-Pond's Usa Co. Skin treatment composition
FR2751541A1 (en) * 1996-07-25 1998-01-30 Fabre Pierre Dermo Cosmetique Topical treatment of alopecia
WO2000040217A1 (en) * 1999-01-08 2000-07-13 Yugenic Limited Partnership Topical composition comprising n-acetylaldosamines or n-acetylamino acids
US6808716B2 (en) 1999-01-08 2004-10-26 Ruey J. Yu N-acetylamino acids, related N-acetyl compounds and their topical use
WO2010000686A2 (en) * 2008-06-30 2010-01-07 Federico Visentini Composition for topical use
CN113651745A (en) * 2021-09-09 2021-11-16 上海医药工业研究院 Buvalracetam intermediate, preparation method and purification method thereof

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2511676A1 (en) * 1981-08-18 1983-02-25 Mollet Marc QUININE PANTOTHENATES, PROCESSES FOR THEIR PREPARATION AND COSMETOLOGICAL PRODUCTS COMPRISING THE SAME
US5296500A (en) * 1991-08-30 1994-03-22 The Procter & Gamble Company Use of N-acetyl-cysteine and derivatives for regulating skin wrinkles and/or skin atrophy
US5451405A (en) * 1994-04-25 1995-09-19 Chesebrough-Pond's Usa Co. Skin treatment composition
FR2751541A1 (en) * 1996-07-25 1998-01-30 Fabre Pierre Dermo Cosmetique Topical treatment of alopecia
US6808716B2 (en) 1999-01-08 2004-10-26 Ruey J. Yu N-acetylamino acids, related N-acetyl compounds and their topical use
US6524593B1 (en) 1999-01-08 2003-02-25 Ruey J. Yu N-acetyl aldosamines and related N-acetyl compounds, and their topical use
WO2000040217A1 (en) * 1999-01-08 2000-07-13 Yugenic Limited Partnership Topical composition comprising n-acetylaldosamines or n-acetylamino acids
USRE41278E1 (en) 1999-01-08 2010-04-27 Yu Ruey J N-acetyl aldosamines and related N-acetyl compounds, and their topical use
USRE41339E1 (en) 1999-01-08 2010-05-18 Tristrata, Inc. N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use
USRE42902E1 (en) 1999-01-08 2011-11-08 Tristrata, Inc. N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use
USRE44302E1 (en) 1999-01-08 2013-06-18 Ruey J. Yu N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use
WO2010000686A2 (en) * 2008-06-30 2010-01-07 Federico Visentini Composition for topical use
WO2010000686A3 (en) * 2008-06-30 2010-03-04 Federico Visentini Composition for topical use comprising quinine
CN113651745A (en) * 2021-09-09 2021-11-16 上海医药工业研究院 Buvalracetam intermediate, preparation method and purification method thereof

Also Published As

Publication number Publication date
FR2244541B1 (en) 1977-09-02

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