FR2244496A1 - 4-(3-Chloro-4-cyclohexylphenyl)-gamma-butyrolactone - with analgesic and antiinflammatory activity - Google Patents

4-(3-Chloro-4-cyclohexylphenyl)-gamma-butyrolactone - with analgesic and antiinflammatory activity

Info

Publication number
FR2244496A1
FR2244496A1 FR7328636A FR7328636A FR2244496A1 FR 2244496 A1 FR2244496 A1 FR 2244496A1 FR 7328636 A FR7328636 A FR 7328636A FR 7328636 A FR7328636 A FR 7328636A FR 2244496 A1 FR2244496 A1 FR 2244496A1
Authority
FR
France
Prior art keywords
cyclohexylphenyl
butyrolactone
chloro
gamma
analgesic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7328636A
Other languages
French (fr)
Other versions
FR2244496B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Clin Midy
Original Assignee
Clin Midy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE2021445A priority Critical patent/DE2021445C3/en
Application filed by Clin Midy filed Critical Clin Midy
Priority to FR7328636A priority patent/FR2244496A1/en
Priority to US489983A priority patent/US3883563A/en
Priority to DE2436484A priority patent/DE2436484A1/en
Priority to AU71835/74A priority patent/AU7183574A/en
Priority to JP49088924A priority patent/JPS5070353A/ja
Priority to NL7410489A priority patent/NL7410489A/en
Priority to BE147291A priority patent/BE818494R/en
Priority to SE7410030A priority patent/SE7410030L/xx
Priority to DK417074A priority patent/DK417074A/da
Publication of FR2244496A1 publication Critical patent/FR2244496A1/en
Application granted granted Critical
Publication of FR2244496B1 publication Critical patent/FR2244496B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

4-(3-chloro-4-cyclohexylphenyl)-gamma-butyrolactone of formula (I) have antiinflammatory and analgesic activity, for human and veterinary use. (I) are prepd. by the action of NaBH4 followed by tosylic acid on a starting prod. of formula I wherein the heterocyclic ring is replaced by -COCH2CH2CO2H.
FR7328636A 1969-05-12 1973-08-06 4-(3-Chloro-4-cyclohexylphenyl)-gamma-butyrolactone - with analgesic and antiinflammatory activity Granted FR2244496A1 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
DE2021445A DE2021445C3 (en) 1969-05-12 1970-05-02 4-phenylbutyric acid derivatives, a process for their preparation and pharmaceuticals
FR7328636A FR2244496A1 (en) 1973-08-06 1973-08-06 4-(3-Chloro-4-cyclohexylphenyl)-gamma-butyrolactone - with analgesic and antiinflammatory activity
US489983A US3883563A (en) 1973-08-06 1974-07-19 4-(4{40 -Cyclohexyl-3{40 -chlorophenyl)-{65 -butyrolactone
DE2436484A DE2436484A1 (en) 1969-05-12 1974-07-29 4- (3-CHLORO-4-CYCLOHEXYL-PHENYL) -GAMMABUTYROLACTONE, METHOD FOR MANUFACTURING IT, AND THIS PHARMACEUTICAL COMPOSITION
AU71835/74A AU7183574A (en) 1973-08-06 1974-07-30 Butyrolactone derivative
JP49088924A JPS5070353A (en) 1973-08-06 1974-08-02
NL7410489A NL7410489A (en) 1973-08-06 1974-08-05 METHOD OF PREPARING A MEDICINAL PRODUCT WITH ANTI-PAIN AND INFLAMMATORY ACTION.
BE147291A BE818494R (en) 1973-08-06 1974-08-05 PHENYL BUTYRIC ACIDS
SE7410030A SE7410030L (en) 1973-08-06 1974-08-05
DK417074A DK417074A (en) 1973-08-06 1974-08-05

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7328636A FR2244496A1 (en) 1973-08-06 1973-08-06 4-(3-Chloro-4-cyclohexylphenyl)-gamma-butyrolactone - with analgesic and antiinflammatory activity

Publications (2)

Publication Number Publication Date
FR2244496A1 true FR2244496A1 (en) 1975-04-18
FR2244496B1 FR2244496B1 (en) 1977-09-02

Family

ID=9123618

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7328636A Granted FR2244496A1 (en) 1969-05-12 1973-08-06 4-(3-Chloro-4-cyclohexylphenyl)-gamma-butyrolactone - with analgesic and antiinflammatory activity

Country Status (7)

Country Link
JP (1) JPS5070353A (en)
AU (1) AU7183574A (en)
BE (1) BE818494R (en)
DK (1) DK417074A (en)
FR (1) FR2244496A1 (en)
NL (1) NL7410489A (en)
SE (1) SE7410030L (en)

Also Published As

Publication number Publication date
SE7410030L (en) 1975-02-07
AU7183574A (en) 1976-02-05
DK417074A (en) 1975-04-14
BE818494R (en) 1975-02-05
JPS5070353A (en) 1975-06-11
NL7410489A (en) 1975-02-10
FR2244496B1 (en) 1977-09-02

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Legal Events

Date Code Title Description
ST Notification of lapse