FR2220273A1 - Sulphur-contg. N-substd nicotinamide derivs - for curing effects of hepatic diseases and reducing arterial pressure - Google Patents
Sulphur-contg. N-substd nicotinamide derivs - for curing effects of hepatic diseases and reducing arterial pressureInfo
- Publication number
- FR2220273A1 FR2220273A1 FR7411339A FR7411339A FR2220273A1 FR 2220273 A1 FR2220273 A1 FR 2220273A1 FR 7411339 A FR7411339 A FR 7411339A FR 7411339 A FR7411339 A FR 7411339A FR 2220273 A1 FR2220273 A1 FR 2220273A1
- Authority
- FR
- France
- Prior art keywords
- substd
- derivs
- contg
- nicotinamide
- sulphur
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
The novel cpds. of formula (I):-(where R is H or opt. substd. alkyl or alkaryl; R1 is an opt. substd. linear or branched aliphatic chain, or an opt. substd. 3-6- membered ring opt. contng. heteroatoms; R2 is H, opt. substd. alkyl or alkaryl, or COR), prepd. by reacting nicotinoyl chloride hydrochloride with the corresp. amine.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT4867573A IT1056032B (en) | 1973-03-08 | 1973-03-08 | NICOTINIC ACID DERIVATIVES WITH VARIOUSLY REPLACED AMINES |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2220273A1 true FR2220273A1 (en) | 1974-10-04 |
FR2220273B1 FR2220273B1 (en) | 1977-05-06 |
Family
ID=11267982
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7411339A Granted FR2220273A1 (en) | 1973-03-08 | 1974-03-29 | Sulphur-contg. N-substd nicotinamide derivs - for curing effects of hepatic diseases and reducing arterial pressure |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR2220273A1 (en) |
IT (1) | IT1056032B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2526431A1 (en) * | 1982-05-10 | 1983-11-10 | Sanofi Sa | N-2-guanidino-thiazolyl methyl:thio-ethyl benzamide and nicotinamide - histamine H2 receptor blockers, used to treat ulcers |
EP0094303A1 (en) * | 1982-05-10 | 1983-11-16 | Sanofi S.A. | Amides, their salts, process for their preparation and pharmaceutical compositions containing them |
-
1973
- 1973-03-08 IT IT4867573A patent/IT1056032B/en active
-
1974
- 1974-03-29 FR FR7411339A patent/FR2220273A1/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2526431A1 (en) * | 1982-05-10 | 1983-11-10 | Sanofi Sa | N-2-guanidino-thiazolyl methyl:thio-ethyl benzamide and nicotinamide - histamine H2 receptor blockers, used to treat ulcers |
EP0094303A1 (en) * | 1982-05-10 | 1983-11-16 | Sanofi S.A. | Amides, their salts, process for their preparation and pharmaceutical compositions containing them |
Also Published As
Publication number | Publication date |
---|---|
FR2220273B1 (en) | 1977-05-06 |
IT1056032B (en) | 1982-01-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |