FR2194434A1 - Bis piperazino-androstanes - as muscle relaxants - Google Patents
Bis piperazino-androstanes - as muscle relaxantsInfo
- Publication number
- FR2194434A1 FR2194434A1 FR7327718A FR7327718A FR2194434A1 FR 2194434 A1 FR2194434 A1 FR 2194434A1 FR 7327718 A FR7327718 A FR 7327718A FR 7327718 A FR7327718 A FR 7327718A FR 2194434 A1 FR2194434 A1 FR 2194434A1
- Authority
- FR
- France
- Prior art keywords
- alpha
- androstanes
- piperazino
- bis
- muscle relaxants
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Title cpds. (I) their salts and quaternary ammonium salts. (where R is H, or 1-6C acyl, R1 is 1-6C alkyl, vinyl, allyl, or hydroxyethyl, R2 is H, 1-6C-alkyl, allyl or benzyl, X is H Y is OH or 1-6C acyloxy or X + Y is O and salt forming anions are Cl, Br, I, OH, mesyloxy or tosyloxy) are prepd. by reacting a 2 alpha, 3 alpha, 16 alpha, 17 alpha diepoxy-5 alpha-androstane with and then opt. reducing and/or a acylating the product.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HURI471A HU165600B (en) | 1972-07-27 | 1972-07-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2194434A1 true FR2194434A1 (en) | 1974-03-01 |
FR2194434B1 FR2194434B1 (en) | 1977-04-15 |
Family
ID=11000894
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7327718A Granted FR2194434A1 (en) | 1972-07-27 | 1973-07-27 | Bis piperazino-androstanes - as muscle relaxants |
Country Status (17)
Country | Link |
---|---|
JP (1) | JPS5231922B2 (en) |
AT (1) | AT327414B (en) |
BE (1) | BE802903A (en) |
CA (1) | CA1023343A (en) |
CS (1) | CS193475B2 (en) |
DD (1) | DD106036A5 (en) |
DE (1) | DE2337882C3 (en) |
DK (1) | DK132662C (en) |
FR (1) | FR2194434A1 (en) |
HU (1) | HU165600B (en) |
IL (1) | IL42600A (en) |
NL (2) | NL174945C (en) |
PL (2) | PL92579B1 (en) |
RO (1) | RO71515A (en) |
SE (1) | SE398506B (en) |
SU (1) | SU582768A3 (en) |
YU (1) | YU35776B (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2318174A1 (en) * | 1975-07-15 | 1977-02-11 | Richter Gedeon Vegyeszet | DIEPOXY-ANDROSTANES AND THEIR PREPARATION |
EP0246469A1 (en) * | 1986-05-03 | 1987-11-25 | Hoechst Aktiengesellschaft | Process for encapsulating biologically active material |
EP0608495A2 (en) * | 1992-11-02 | 1994-08-03 | Ltd. Maruishi Pharmaceutical Co. | Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU172521B (en) * | 1975-08-01 | 1978-09-28 | Richter Gedeon Vegyeszet | Process for producing new triamino-androstane derivatives and quaternary salts thereof |
WO2006038047A1 (en) * | 2004-10-07 | 2006-04-13 | Richter Gedeon Vegyészeti Gyár Rt. | Environment-friend process for the synthesis of quaternary ammonio-steroιds |
-
1972
- 1972-07-27 HU HURI471A patent/HU165600B/hu unknown
-
1973
- 1973-06-26 IL IL42600A patent/IL42600A/en unknown
- 1973-07-04 AT AT589173A patent/AT327414B/en not_active IP Right Cessation
- 1973-07-23 CS CS735251A patent/CS193475B2/en unknown
- 1973-07-24 SE SE7310295A patent/SE398506B/en unknown
- 1973-07-24 DD DD172557A patent/DD106036A5/xx unknown
- 1973-07-25 PL PL1973183828A patent/PL92579B1/en unknown
- 1973-07-25 PL PL1973164288A patent/PL89360B1/en unknown
- 1973-07-26 DE DE2337882A patent/DE2337882C3/en not_active Expired
- 1973-07-26 CA CA177,348A patent/CA1023343A/en not_active Expired
- 1973-07-26 NL NLAANVRAGE7310389,A patent/NL174945C/en active Protection Beyond IP Right Term
- 1973-07-26 DK DK412473*A patent/DK132662C/en active Protection Beyond IP Right Term
- 1973-07-26 RO RO7375603A patent/RO71515A/en unknown
- 1973-07-26 SU SU7301953816A patent/SU582768A3/en active
- 1973-07-27 JP JP48084795A patent/JPS5231922B2/ja not_active Expired
- 1973-07-27 YU YU2052/73A patent/YU35776B/en unknown
- 1973-07-27 BE BE133964A patent/BE802903A/en active Protection Beyond IP Right Term
- 1973-07-27 FR FR7327718A patent/FR2194434A1/en active Granted
-
1993
- 1993-06-24 NL NL930088C patent/NL930088I2/en unknown
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2318174A1 (en) * | 1975-07-15 | 1977-02-11 | Richter Gedeon Vegyeszet | DIEPOXY-ANDROSTANES AND THEIR PREPARATION |
EP0246469A1 (en) * | 1986-05-03 | 1987-11-25 | Hoechst Aktiengesellschaft | Process for encapsulating biologically active material |
EP0608495A2 (en) * | 1992-11-02 | 1994-08-03 | Ltd. Maruishi Pharmaceutical Co. | Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same |
EP0608495A3 (en) * | 1992-11-02 | 1995-12-20 | Zoltan Tuba | Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same. |
US5591735A (en) * | 1992-11-02 | 1997-01-07 | Marvishi Pharmaceutical Co., Ltd. | Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same |
Also Published As
Publication number | Publication date |
---|---|
NL7310389A (en) | 1974-01-29 |
SU582768A3 (en) | 1977-11-30 |
CS193475B2 (en) | 1979-10-31 |
NL174945C (en) | 1984-09-03 |
SE398506B (en) | 1977-12-27 |
DE2337882C3 (en) | 1979-02-15 |
BE802903A (en) | 1973-11-16 |
DK132662B (en) | 1976-01-19 |
YU35776B (en) | 1981-06-30 |
DE2337882B2 (en) | 1978-06-08 |
NL174945B (en) | 1984-04-02 |
NL930088I2 (en) | 1994-02-16 |
DD106036A5 (en) | 1974-05-20 |
DE2337882A1 (en) | 1974-02-07 |
JPS5231922B2 (en) | 1977-08-18 |
IL42600A (en) | 1977-05-31 |
AT327414B (en) | 1976-01-26 |
DK132662C (en) | 1976-08-02 |
JPS4992081A (en) | 1974-09-03 |
ATA589173A (en) | 1975-04-15 |
NL930088I1 (en) | 1993-10-01 |
YU205273A (en) | 1980-10-31 |
FR2194434B1 (en) | 1977-04-15 |
CA1023343A (en) | 1977-12-27 |
PL89360B1 (en) | 1976-11-30 |
HU165600B (en) | 1974-09-28 |
PL92579B1 (en) | 1977-04-30 |
AU5750973A (en) | 1975-01-09 |
RO71515A (en) | 1982-10-26 |
IL42600A0 (en) | 1973-08-29 |
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