FR2159246A1 - Antibiotic g-418 and verdamycin i - produced by fermentation of micromonospora rhodorangea or m grisea - Google Patents
Antibiotic g-418 and verdamycin i - produced by fermentation of micromonospora rhodorangea or m griseaInfo
- Publication number
- FR2159246A1 FR2159246A1 FR7229471A FR7229471A FR2159246A1 FR 2159246 A1 FR2159246 A1 FR 2159246A1 FR 7229471 A FR7229471 A FR 7229471A FR 7229471 A FR7229471 A FR 7229471A FR 2159246 A1 FR2159246 A1 FR 2159246A1
- Authority
- FR
- France
- Prior art keywords
- verdamycin
- grisea
- antibiotic
- fermentation
- produced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
- C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Antibiotic G-418 is of formula (I): (where R1, R2 and R3 are OH and is a single bond), and verdamycin I is of formula (I) (where R1 is NH2 R2 and R3 is H, and is a double bond). The acid addn salts and oxazolidine Schiff-base derivs of G-418 and verdamycin (I) are also claimed. The fermentation of M. rhodorangea or M. grisea also produces the known antibiotics sisomycin and gentamycin A.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19670771A | 1971-11-08 | 1971-11-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2159246A1 true FR2159246A1 (en) | 1973-06-22 |
FR2159246B1 FR2159246B1 (en) | 1976-03-05 |
Family
ID=22726520
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7229471A Granted FR2159246A1 (en) | 1971-11-08 | 1972-08-17 | Antibiotic g-418 and verdamycin i - produced by fermentation of micromonospora rhodorangea or m grisea |
Country Status (20)
Country | Link |
---|---|
JP (1) | JPS4852991A (en) |
AR (1) | AR193286A1 (en) |
AT (1) | AT319469B (en) |
BE (1) | BE787758A (en) |
CA (1) | CA972303A (en) |
CH (1) | CH586281A5 (en) |
CS (1) | CS163282B2 (en) |
DD (1) | DD102161A5 (en) |
DE (1) | DE2239964A1 (en) |
DK (1) | DK130847B (en) |
FR (1) | FR2159246A1 (en) |
IL (1) | IL40151A (en) |
LU (1) | LU65922A1 (en) |
NL (1) | NL7211265A (en) |
NO (1) | NO136050C (en) |
OA (1) | OA04260A (en) |
PH (1) | PH13016A (en) |
PL (1) | PL84893B1 (en) |
RO (1) | RO58761A (en) |
SE (1) | SE384691B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2201872A1 (en) * | 1972-10-10 | 1974-05-03 | Scherico Ltd |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2068518A1 (en) * | 1969-08-25 | 1971-08-27 | Scherico Ltd | |
FR2104762A1 (en) * | 1970-06-22 | 1972-04-21 | Scherico Ltd |
-
0
- BE BE787758D patent/BE787758A/en unknown
-
1972
- 1972-08-14 DE DE2239964A patent/DE2239964A1/en active Pending
- 1972-08-16 CH CH1211472A patent/CH586281A5/xx not_active IP Right Cessation
- 1972-08-17 SE SE7210703A patent/SE384691B/en unknown
- 1972-08-17 NL NL7211265A patent/NL7211265A/xx not_active Application Discontinuation
- 1972-08-17 NO NO2955/72A patent/NO136050C/en unknown
- 1972-08-17 PH PH13813A patent/PH13016A/en unknown
- 1972-08-17 FR FR7229471A patent/FR2159246A1/en active Granted
- 1972-08-17 RO RO71981A patent/RO58761A/ro unknown
- 1972-08-17 IL IL40151A patent/IL40151A/en unknown
- 1972-08-17 CS CS5710A patent/CS163282B2/cs unknown
- 1972-08-17 DK DK407772AA patent/DK130847B/en unknown
- 1972-08-17 CA CA149,843A patent/CA972303A/en not_active Expired
- 1972-08-17 AT AT712272A patent/AT319469B/en not_active IP Right Cessation
- 1972-08-17 PL PL1972157318A patent/PL84893B1/pl unknown
- 1972-08-17 DD DD165307A patent/DD102161A5/xx unknown
- 1972-08-18 LU LU65922A patent/LU65922A1/xx unknown
- 1972-08-18 JP JP47082680A patent/JPS4852991A/ja active Pending
- 1972-08-18 OA OA54666A patent/OA04260A/en unknown
- 1972-08-18 AR AR243622A patent/AR193286A1/en active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2068518A1 (en) * | 1969-08-25 | 1971-08-27 | Scherico Ltd | |
FR2104762A1 (en) * | 1970-06-22 | 1972-04-21 | Scherico Ltd |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2201872A1 (en) * | 1972-10-10 | 1974-05-03 | Scherico Ltd |
Also Published As
Publication number | Publication date |
---|---|
BE787758A (en) | 1973-02-19 |
CH586281A5 (en) | 1977-03-31 |
OA04260A (en) | 1979-12-31 |
CA972303A (en) | 1975-08-05 |
NO136050C (en) | 1977-07-13 |
DK130847B (en) | 1975-04-21 |
DK130847C (en) | 1975-09-29 |
DD102161A5 (en) | 1973-12-05 |
PL84893B1 (en) | 1976-04-30 |
CS163282B2 (en) | 1975-08-29 |
IL40151A (en) | 1976-01-30 |
IL40151A0 (en) | 1972-10-29 |
RO58761A (en) | 1975-12-15 |
FR2159246B1 (en) | 1976-03-05 |
JPS4852991A (en) | 1973-07-25 |
NO136050B (en) | 1977-04-04 |
AR193286A1 (en) | 1973-04-11 |
NL7211265A (en) | 1973-05-10 |
DE2239964A1 (en) | 1973-06-14 |
PH13016A (en) | 1979-11-09 |
LU65922A1 (en) | 1973-01-15 |
SE384691B (en) | 1976-05-17 |
AT319469B (en) | 1974-12-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |