FR2153202A1 - Triiodothyroacetic acid salts prepn - with metals and organic bases - Google Patents

Triiodothyroacetic acid salts prepn - with metals and organic bases

Info

Publication number
FR2153202A1
FR2153202A1 FR7134447A FR7134447A FR2153202A1 FR 2153202 A1 FR2153202 A1 FR 2153202A1 FR 7134447 A FR7134447 A FR 7134447A FR 7134447 A FR7134447 A FR 7134447A FR 2153202 A1 FR2153202 A1 FR 2153202A1
Authority
FR
France
Prior art keywords
salts
salt
activity
soluble
triiodothyroacetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7134447A
Other languages
French (fr)
Other versions
FR2153202B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Industrie Chimique
Original Assignee
Industrie Chimique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Industrie Chimique filed Critical Industrie Chimique
Priority to FR7134447A priority Critical patent/FR2153202A1/en
Priority to DE19722239136 priority patent/DE2239136A1/en
Publication of FR2153202A1 publication Critical patent/FR2153202A1/en
Application granted granted Critical
Publication of FR2153202B1 publication Critical patent/FR2153202B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Title salts of formula (I): (in which M is (1) an alkali metal or the cation of an org. base (salts soluble in water) or (2) one gram-equiv. or a metal other than an alkali metal (water-insol. salts)) are prepd. (1) by reacting triiodothyroacetic acid in alcoholic-aq. soln in the cold with the stoichiometric amt. of an alkali base or an organic base, evaporating the resulting soln. in vacuo, and comminuting and drying the resulting salt, or (2) by reacting a soluble salt of triiodothyroacetic acid in alcoholic-aq. soln. in the cold with a soluble salt of a metal other than an alkali metal salt, and filtering off, washing and drying the pptd. salt. The salts have hypolipaemic and hypocholesterolaemic activity and activity against cellulitis. The soluble salts can be used in injections, and when applied topically give improved percutaneous absorption. Where the cation is pharmacologically active. this activity is allied with the activity of triiodothyroacetic-acid.
FR7134447A 1971-09-24 1971-09-24 Triiodothyroacetic acid salts prepn - with metals and organic bases Granted FR2153202A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR7134447A FR2153202A1 (en) 1971-09-24 1971-09-24 Triiodothyroacetic acid salts prepn - with metals and organic bases
DE19722239136 DE2239136A1 (en) 1971-09-24 1972-08-09 4- (4'-HYDROXY-3'-IODO-PHENOXY) -3,5DIIODOPHENYL ACID SALT AND METHOD FOR THEIR PRODUCTION

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7134447A FR2153202A1 (en) 1971-09-24 1971-09-24 Triiodothyroacetic acid salts prepn - with metals and organic bases

Publications (2)

Publication Number Publication Date
FR2153202A1 true FR2153202A1 (en) 1973-05-04
FR2153202B1 FR2153202B1 (en) 1975-03-14

Family

ID=9083448

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7134447A Granted FR2153202A1 (en) 1971-09-24 1971-09-24 Triiodothyroacetic acid salts prepn - with metals and organic bases

Country Status (2)

Country Link
DE (1) DE2239136A1 (en)
FR (1) FR2153202A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996040048A2 (en) * 1995-06-07 1996-12-19 Karo Bio Ab Novel uses for thyroid hormones or thyroid hormone-like compounds
US6380255B1 (en) 1995-06-07 2002-04-30 Karo Bio Ab Treatment for dermal skin atrophy using thyroid hormone compounds or thyroid hormone-like compounds

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6677473B1 (en) 1999-11-19 2004-01-13 Corvas International Inc Plasminogen activator inhibitor antagonists
US6638977B1 (en) * 1999-11-19 2003-10-28 Corvas International, Inc. Plasminogen activator inhibitor antagonists

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996040048A2 (en) * 1995-06-07 1996-12-19 Karo Bio Ab Novel uses for thyroid hormones or thyroid hormone-like compounds
WO1996040048A3 (en) * 1995-06-07 1997-11-13 Karobio Ab Novel uses for thyroid hormones or thyroid hormone-like compounds
US6380255B1 (en) 1995-06-07 2002-04-30 Karo Bio Ab Treatment for dermal skin atrophy using thyroid hormone compounds or thyroid hormone-like compounds
EP1398024A3 (en) * 1995-06-07 2004-12-15 Karo Bio Ab uses for thyroid hormones compounds

Also Published As

Publication number Publication date
FR2153202B1 (en) 1975-03-14
DE2239136A1 (en) 1973-03-29

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Legal Events

Date Code Title Description
ST Notification of lapse