FR2133484A2 - 3-17 and 21-sulphonyloxy-steroids - with androgenic anabolic progestogenic and oestrogen activity of long duration - Google Patents

3-17 and 21-sulphonyloxy-steroids - with androgenic anabolic progestogenic and oestrogen activity of long duration

Info

Publication number
FR2133484A2
FR2133484A2 FR7113151A FR7113151A FR2133484A2 FR 2133484 A2 FR2133484 A2 FR 2133484A2 FR 7113151 A FR7113151 A FR 7113151A FR 7113151 A FR7113151 A FR 7113151A FR 2133484 A2 FR2133484 A2 FR 2133484A2
Authority
FR
France
Prior art keywords
progestogenic
sulphonyloxy
steroids
long duration
oestrogen activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7113151A
Other languages
French (fr)
Other versions
FR2133484B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jenapharm GmbH and Co KG
Original Assignee
VEB Jenapharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR6913709A external-priority patent/FR2036997A1/en
Application filed by VEB Jenapharm filed Critical VEB Jenapharm
Priority to FR7113151A priority Critical patent/FR2133484A2/en
Publication of FR2133484A2 publication Critical patent/FR2133484A2/en
Application granted granted Critical
Publication of FR2133484B2 publication Critical patent/FR2133484B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic

Abstract

Cpds. of formulae I, II or III: where R1 is alkyl (C2-C8, cycloalkyl, aralkyl, N,N-dialkylamino, or polymethyleneimino; R2 is H, Et, -CH=CH2, -C=CH, -C=C-Cl; R3 is OH, -o. acyl, -O-alkyl, -O.SiMe3; R2+R3 are =O; R4 = H, Cl; R5 = H, Me; R6 = H2 or =O; R7 = alpha-H, beta-O.SO2R1 or alpha-OH, beta-CO.CH2O.SO2.R1; R8 = CO.Me or C8H17. They are prepared by esterification of the corresp. 3-, 17- or 21-ols with R1.SO2.X where X is halogen.
FR7113151A 1969-04-29 1971-04-14 3-17 and 21-sulphonyloxy-steroids - with androgenic anabolic progestogenic and oestrogen activity of long duration Granted FR2133484A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7113151A FR2133484A2 (en) 1969-04-29 1971-04-14 3-17 and 21-sulphonyloxy-steroids - with androgenic anabolic progestogenic and oestrogen activity of long duration

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR6913709A FR2036997A1 (en) 1969-04-29 1969-04-29 Thermpentic steroidal sulphonate esters
FR7113151A FR2133484A2 (en) 1969-04-29 1971-04-14 3-17 and 21-sulphonyloxy-steroids - with androgenic anabolic progestogenic and oestrogen activity of long duration

Publications (2)

Publication Number Publication Date
FR2133484A2 true FR2133484A2 (en) 1972-12-01
FR2133484B2 FR2133484B2 (en) 1974-08-02

Family

ID=26214984

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7113151A Granted FR2133484A2 (en) 1969-04-29 1971-04-14 3-17 and 21-sulphonyloxy-steroids - with androgenic anabolic progestogenic and oestrogen activity of long duration

Country Status (1)

Country Link
FR (1) FR2133484A2 (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993005063A1 (en) * 1991-08-29 1993-03-18 Imperial College Of Science, Technology And Medicine Steroid sulphatase inhibitors
WO1996005217A1 (en) * 1994-08-09 1996-02-22 Jenapharm Gmbh Pharmaceutical compositions containing estra-1,3,5(10)-triene derivatives
WO1996005216A1 (en) * 1994-08-09 1996-02-22 Jenapharm Gmbh Estra-1,3,5(10)-triene derivatives, methods of preparing such compounds and pharmaceutical compositions containing them
WO1997014712A2 (en) * 1995-10-19 1997-04-24 Jenapharm Gmbh Sulphamate derivatives of 1,3,5(10)-estratriene derivatives, methods of producing them and pharmaceutical compounds containing them
US6011024A (en) * 1991-08-28 2000-01-04 Imperial College Of Science Technology & Medicine Steroid sulphatase inhibitors
US6642220B1 (en) 1996-12-05 2003-11-04 Sterix Limited Compounds that inhibit oestrone sulphatase; compositions thereof; and methods employing the same
US7098199B2 (en) 1991-08-29 2006-08-29 Sterix Limited Steroid sulphatase inhibitors

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011024A (en) * 1991-08-28 2000-01-04 Imperial College Of Science Technology & Medicine Steroid sulphatase inhibitors
US6642397B1 (en) 1991-08-28 2003-11-04 Sterix Limited Steroid sulphatase inhibitors
US7098199B2 (en) 1991-08-29 2006-08-29 Sterix Limited Steroid sulphatase inhibitors
US5604215A (en) * 1991-08-29 1997-02-18 Imperial College Of Science, Technology And Medicine Steroid sulphatase inhibitors
WO1993005063A1 (en) * 1991-08-29 1993-03-18 Imperial College Of Science, Technology And Medicine Steroid sulphatase inhibitors
EP1273590A2 (en) * 1994-08-09 2003-01-08 Jenapharm GmbH & Co. KG Estra- 1,3,5(10)-triene Derivatives, Methods of Preparing Such Compounds and Pharmaceutical Compositions Containing Them
US6080735A (en) * 1994-08-09 2000-06-27 Jenapharm Gmbh & Co. Kg Estra-1,3,5(10)-trien derivatives, processes for their preparation and pharmaceutical compositions containing these compounds
EP1284273A2 (en) * 1994-08-09 2003-02-19 JENAPHARM GmbH Estra-1,3,5(10)-trien-3-sulfamates a process for their production and pharmaceutical compositions containing them
WO1996005216A1 (en) * 1994-08-09 1996-02-22 Jenapharm Gmbh Estra-1,3,5(10)-triene derivatives, methods of preparing such compounds and pharmaceutical compositions containing them
EP1284273A3 (en) * 1994-08-09 2004-07-21 Schering AG Estra-1,3,5(10)-trien-3-sulfamates a process for their production and pharmaceutical compositions containing them
EP1273590A3 (en) * 1994-08-09 2004-07-28 Schering AG Estra- 1,3,5(10)-triene Derivatives, Methods of Preparing Such Compounds and Pharmaceutical Compositions Containing Them
WO1996005217A1 (en) * 1994-08-09 1996-02-22 Jenapharm Gmbh Pharmaceutical compositions containing estra-1,3,5(10)-triene derivatives
WO1997014712A3 (en) * 1995-10-19 1997-06-05 Jenapharm Gmbh Sulphamate derivatives of 1,3,5(10)-estratriene derivatives, methods of producing them and pharmaceutical compounds containing them
WO1997014712A2 (en) * 1995-10-19 1997-04-24 Jenapharm Gmbh Sulphamate derivatives of 1,3,5(10)-estratriene derivatives, methods of producing them and pharmaceutical compounds containing them
CN1125077C (en) * 1995-10-19 2003-10-22 杰纳法姆两合公司 Sulphamate derivatives of 1,3,5(10)-estratriene derivatives, methods of producing them and pharmaceutical compounds containing them
US6642220B1 (en) 1996-12-05 2003-11-04 Sterix Limited Compounds that inhibit oestrone sulphatase; compositions thereof; and methods employing the same

Also Published As

Publication number Publication date
FR2133484B2 (en) 1974-08-02

Similar Documents

Publication Publication Date Title
OA05185A (en) Absorbent blend of cellulose and graft polysaccharide.
FR2133484A2 (en) 3-17 and 21-sulphonyloxy-steroids - with androgenic anabolic progestogenic and oestrogen activity of long duration
BE866464A (en) ADVANCED ACELLULAR VACCINES CONTAINING CAPSULAR POLYSACCHARIDES.
ES298740A1 (en) Procedure for the preparation of etheries (Machine-translation by Google Translate, not legally binding)
AT341813B (en) AUTOMATIC GAS LIGHTER
ATA281576A (en) LOWER GUIDE BODY FOR SLIDING SIDEWAYS HANGING PARTITION WALLS OF DAMP ROOMS
ES436864A1 (en) Amino-2 imidazoles
AT334569B (en) FASTENING OF GUIDE RAILS TO DRAWERS
AT326865B (en) GUIDE RAIL FOR DRAWERS
BE830566A (en) MOUTH-TRAINING FLASH REDUCTION AGENT OF POWDER-LOADED FIREARMS
ES425686A1 (en) 6-Aza-3H-1,4-benzodiazepines
ES442182A1 (en) O,S-dialkyl O-sulfonyloxy-phenyl phosphorothiolates and phosphorodithioates
FR2137931A1 (en) 2,3-disubstd-quinoxaline-1,4-dioxides - bactericides and amoebicides
AT332589B (en) ANCHORING FOR DRAWER GUIDE RAILS
BE824716A (en) BIS - ((N-HYDROXYALKYL) -AMINOALKYLTHIO) -ALKANES AND DERIVATIVES
AT332149B (en) AUTOMATIC GAS LIGHTER
NL7505567A (en) CARTRIDGE FEEDER TO AN AUTOMATIC FIREARMS.
BE817187R (en) Ovens
FR2124497A1 (en) 2-amino-3-pyridylcarbonyl-thiophene derivs - analgesics and anti-inflammatory agents
SE386732B (en) RECOPERATIVE THERMAL-CATALYTIC SMOKE COMBUSTION OVEN
ES80960U (en) Folding rack perfected (Machine-translation by Google Translate, not legally binding)
SU500457A1 (en) Latching device of closed ore-smelting furnaces
IT1051557B (en) 1,1-dithienyl (3)-propane derivs - for treatment of heart and circula diseases
SE415950B (en) APPLIANCES FOR BUNCHING OF CHECKS, LONG STRAPS AND SIMILAR LONG STRENGTHS
ES201910U (en) Improved hinge (Machine-translation by Google Translate, not legally binding)