FR2132521A1 - Effervescent tablets prdn - by controlled drying in effervescent granule formation - Google Patents
Effervescent tablets prdn - by controlled drying in effervescent granule formationInfo
- Publication number
- FR2132521A1 FR2132521A1 FR7112175A FR7112175A FR2132521A1 FR 2132521 A1 FR2132521 A1 FR 2132521A1 FR 7112175 A FR7112175 A FR 7112175A FR 7112175 A FR7112175 A FR 7112175A FR 2132521 A1 FR2132521 A1 FR 2132521A1
- Authority
- FR
- France
- Prior art keywords
- effervescent
- prdn
- mixt
- controlled drying
- granule formation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Abstract
The product, which contains >=1 medicament and an effervescent mix of an alkali metal bicarbonate and an aliphatic polycarboxylic acid is prepd. by (1) dampening the effervescent mixt. opt. contng. the medicament with 1 wt.% (w.r.t. the bicarbonate) water (2) pre-drying the damp mixt. in a fluidised bed with warm air (contng. is not 5 g./m.3 water) at 60 degrees F. and (3) finally drying the granulated mixt. at under (2). The process prevents chemical reaction and loss of CO2 during granulation.
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7112175A FR2132521A1 (en) | 1971-04-06 | 1971-04-06 | Effervescent tablets prdn - by controlled drying in effervescent granule formation |
GB1381672A GB1359614A (en) | 1971-04-06 | 1972-03-24 | Method for the manufacture of effervescent tablets |
CA138,565A CA978477A (en) | 1971-04-06 | 1972-03-28 | Method for the manufacture of effervescent tablets |
ES401283A ES401283A1 (en) | 1971-04-06 | 1972-03-28 | Method for the manufacture of effervescent tablets |
BE781358A BE781358A (en) | 1971-04-06 | 1972-03-29 | PERFECTED PROCESS FOR MANUFACTURING EFFERVESCENT TABLETS |
ZA722147A ZA722147B (en) | 1971-04-06 | 1972-03-29 | Improved method for the manufacture of effervescent tablets |
AT280072A AT329763B (en) | 1971-04-06 | 1972-03-30 | Process for the manufacture of effervescent tablets |
DE2216072A DE2216072C2 (en) | 1971-04-06 | 1972-04-01 | Process for the production of effervescent tablets |
AU40683/72A AU464567B2 (en) | 1971-04-06 | 1972-04-04 | Improved method forthe manufacture of effervescent tablets |
NLAANVRAGE7204524,A NL176742C (en) | 1971-04-06 | 1972-04-05 | METHOD FOR MANUFACTURING effervescent tablets |
SE7204343A SE378988B (en) | 1971-04-06 | 1972-04-05 | |
DK165072A DK132988C (en) | 1971-04-06 | 1972-04-05 | PROCEDURE FOR MAKING SHOWER TABLETS |
CH505072A CH571322A5 (en) | 1971-04-06 | 1972-04-06 | |
JP3481672A JPS5734249B1 (en) | 1971-04-06 | 1972-04-06 | |
US00241772A US3773922A (en) | 1971-04-06 | 1972-04-06 | Method for the manufacture of effervescent tablets |
DK572573A DK132574C (en) | 1971-04-06 | 1973-10-22 | PROCEDURE FOR MAKING SHOWER TABLETS |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7112175A FR2132521A1 (en) | 1971-04-06 | 1971-04-06 | Effervescent tablets prdn - by controlled drying in effervescent granule formation |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2132521A1 true FR2132521A1 (en) | 1972-11-24 |
FR2132521B1 FR2132521B1 (en) | 1974-08-02 |
Family
ID=9074850
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7112175A Granted FR2132521A1 (en) | 1971-04-06 | 1971-04-06 | Effervescent tablets prdn - by controlled drying in effervescent granule formation |
Country Status (3)
Country | Link |
---|---|
AT (1) | AT329763B (en) |
FR (1) | FR2132521A1 (en) |
ZA (1) | ZA722147B (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2412310A1 (en) * | 1977-12-23 | 1979-07-20 | Fisons Ltd | PHARMACEUTICAL TABLET CONTAINING 1,3-BIS (2-CARBOXYCHROMONE-5-YLOXY) -2-HYDROXYPROPANE, USEFUL FOR THE TREATMENT OF GASTROINTESTINAL AFFECTIONS |
EP0076340A1 (en) * | 1981-10-06 | 1983-04-13 | Gerhard Dr. Gergely | Process for manufacturing effervescent granules which may be transformed, when required, into effervescent tablets |
FR2593065A1 (en) * | 1986-01-22 | 1987-07-24 | Smith Kline French Lab | EFFERVESCENT COUPLES, EFFERVESCENT COMPOSITIONS OF HISTAMINE H2 ANTAGONISTS CONTAINING THEM AND THEIR PREPARATION. |
AT394492B (en) * | 1982-12-21 | 1992-04-10 | Bru Nicole | METHOD AND DEVICE FOR PRODUCING FOAMING TABLETS |
EP0673644A1 (en) * | 1994-03-18 | 1995-09-27 | E-PHARMA TRENTO S.p.A. | Process and plant for preparation of effervescent granules |
FR2796841A1 (en) * | 1999-07-28 | 2001-02-02 | Lipha | Preparation of effervescent tablets in which the acid-carbonate mixture is moistened to commence the exothermic reaction, then dried to prevent further reaction |
FR2816518A1 (en) * | 2000-11-16 | 2002-05-17 | Bionatec | Manufacture of coated granules for aromatic, cosmetic and other purposes uses three-stage drying in warm/hot/warm gas flow |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE59106B1 (en) * | 1985-05-31 | 1994-01-12 | Warner Lambert Co | A therapeutic effervescent composition and a method of preparing the same |
-
1971
- 1971-04-06 FR FR7112175A patent/FR2132521A1/en active Granted
-
1972
- 1972-03-29 ZA ZA722147A patent/ZA722147B/en unknown
- 1972-03-30 AT AT280072A patent/AT329763B/en not_active IP Right Cessation
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2412310A1 (en) * | 1977-12-23 | 1979-07-20 | Fisons Ltd | PHARMACEUTICAL TABLET CONTAINING 1,3-BIS (2-CARBOXYCHROMONE-5-YLOXY) -2-HYDROXYPROPANE, USEFUL FOR THE TREATMENT OF GASTROINTESTINAL AFFECTIONS |
EP0076340A1 (en) * | 1981-10-06 | 1983-04-13 | Gerhard Dr. Gergely | Process for manufacturing effervescent granules which may be transformed, when required, into effervescent tablets |
AT394492B (en) * | 1982-12-21 | 1992-04-10 | Bru Nicole | METHOD AND DEVICE FOR PRODUCING FOAMING TABLETS |
FR2593065A1 (en) * | 1986-01-22 | 1987-07-24 | Smith Kline French Lab | EFFERVESCENT COUPLES, EFFERVESCENT COMPOSITIONS OF HISTAMINE H2 ANTAGONISTS CONTAINING THEM AND THEIR PREPARATION. |
EP0233853A1 (en) * | 1986-01-22 | 1987-08-26 | Laboratoires SMITH KLINE & FRENCH | Effervescent couples, effervescent compositions of H2-antagonists of histamine and their preparation |
EP0673644A1 (en) * | 1994-03-18 | 1995-09-27 | E-PHARMA TRENTO S.p.A. | Process and plant for preparation of effervescent granules |
FR2796841A1 (en) * | 1999-07-28 | 2001-02-02 | Lipha | Preparation of effervescent tablets in which the acid-carbonate mixture is moistened to commence the exothermic reaction, then dried to prevent further reaction |
FR2816518A1 (en) * | 2000-11-16 | 2002-05-17 | Bionatec | Manufacture of coated granules for aromatic, cosmetic and other purposes uses three-stage drying in warm/hot/warm gas flow |
WO2002040144A1 (en) * | 2000-11-16 | 2002-05-23 | Bionatec S.A. | Method for making granules |
US7674496B2 (en) | 2000-11-16 | 2010-03-09 | Laboratoires Docteur Gaetano Zannini | Method for making granules |
Also Published As
Publication number | Publication date |
---|---|
AT329763B (en) | 1976-05-25 |
FR2132521B1 (en) | 1974-08-02 |
ATA280072A (en) | 1975-08-15 |
ZA722147B (en) | 1973-01-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CL | Concession to grant licences | ||
CA | Change of address | ||
ST | Notification of lapse |