FR2122325A2 - Polynucleic acid/polycationic compounds - for potentiating antiviral vaccines - Google Patents
Polynucleic acid/polycationic compounds - for potentiating antiviral vaccinesInfo
- Publication number
- FR2122325A2 FR2122325A2 FR7101815A FR7101815A FR2122325A2 FR 2122325 A2 FR2122325 A2 FR 2122325A2 FR 7101815 A FR7101815 A FR 7101815A FR 7101815 A FR7101815 A FR 7101815A FR 2122325 A2 FR2122325 A2 FR 2122325A2
- Authority
- FR
- France
- Prior art keywords
- polynucleic acid
- potentiating
- polycationic compounds
- antiviral vaccines
- vaccines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Method of potentiating the antigenic response in man and animals, notably to vaccines which may contain additives by incorporating in the vaccine a reaction product of a polynucleic acid with a polycation. Suitable polycationic substances include diethylaminoethyl-dextran with a molecular weight of 103 to 108 pref. 104 to 107. Pref. polynucleic acids are polyinosinic (I), polycytidylic (c), polyuridylic (u) and polyadenylic acid (A).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7101815A FR2122325A2 (en) | 1971-01-20 | 1971-01-20 | Polynucleic acid/polycationic compounds - for potentiating antiviral vaccines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7101815A FR2122325A2 (en) | 1971-01-20 | 1971-01-20 | Polynucleic acid/polycationic compounds - for potentiating antiviral vaccines |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2122325A2 true FR2122325A2 (en) | 1972-09-01 |
FR2122325B2 FR2122325B2 (en) | 1974-08-23 |
Family
ID=9070579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7101815A Granted FR2122325A2 (en) | 1971-01-20 | 1971-01-20 | Polynucleic acid/polycationic compounds - for potentiating antiviral vaccines |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2122325A2 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2328479A1 (en) * | 1975-10-22 | 1977-05-20 | Beecham Group Ltd | Antiviral ionic complex of linear polyarginine - and natural double-chain ribonucleic acid or its derivative |
EP0009498A1 (en) * | 1978-01-16 | 1980-04-16 | Univ Boston | Effecting cellular uptake of molecules. |
WO1996021036A2 (en) * | 1994-12-30 | 1996-07-11 | Chiron Viagene, Inc. | Nucleic acid condensing agents with reduced immunogenicity |
-
1971
- 1971-01-20 FR FR7101815A patent/FR2122325A2/en active Granted
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2328479A1 (en) * | 1975-10-22 | 1977-05-20 | Beecham Group Ltd | Antiviral ionic complex of linear polyarginine - and natural double-chain ribonucleic acid or its derivative |
EP0009498A1 (en) * | 1978-01-16 | 1980-04-16 | Univ Boston | Effecting cellular uptake of molecules. |
EP0009498A4 (en) * | 1978-01-16 | 1980-10-16 | Univ Boston | Effecting cellular uptake of molecules. |
WO1996021036A2 (en) * | 1994-12-30 | 1996-07-11 | Chiron Viagene, Inc. | Nucleic acid condensing agents with reduced immunogenicity |
WO1996021036A3 (en) * | 1994-12-30 | 1996-09-06 | Viagene Inc | Nucleic acid condensing agents with reduced immunogenicity |
Also Published As
Publication number | Publication date |
---|---|
FR2122325B2 (en) | 1974-08-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TP | Transmission of property | ||
GC | Lien (pledge) constituted |