FR2112098A1 - Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity - Google Patents

Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity

Info

Publication number
FR2112098A1
FR2112098A1 FR7039458A FR7039458A FR2112098A1 FR 2112098 A1 FR2112098 A1 FR 2112098A1 FR 7039458 A FR7039458 A FR 7039458A FR 7039458 A FR7039458 A FR 7039458A FR 2112098 A1 FR2112098 A1 FR 2112098A1
Authority
FR
France
Prior art keywords
glucosides
hypocholesterolaemic
vascular system
protective activity
acid esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7039458A
Other languages
French (fr)
Other versions
FR2112098B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SOBIO LAB
Original Assignee
SOBIO LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SOBIO LAB filed Critical SOBIO LAB
Priority to FR7039458A priority Critical patent/FR2112098A1/en
Publication of FR2112098A1 publication Critical patent/FR2112098A1/en
Application granted granted Critical
Publication of FR2112098B1 publication Critical patent/FR2112098B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06Benzopyran radicals
    • C07H17/065Benzo[b]pyrans
    • C07H17/07Benzo[b]pyran-4-ones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

The 2-p-chlorophenoxy-2-methylpropionate esters of esculoside (I), rutoside (II) and hesperidin methyl chalcone (III) are claimed. The penta-ester of (I), deca-ester of (II) and poly-ester of (III) combined the hypocholesterolaemic activity of clofibrate with the vascular system protective activity of the glucosides. The esters are prepd. by adding the acid chloride to a soln. of the glucoside in pyridine.
FR7039458A 1970-11-03 1970-11-03 Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity Granted FR2112098A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7039458A FR2112098A1 (en) 1970-11-03 1970-11-03 Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7039458A FR2112098A1 (en) 1970-11-03 1970-11-03 Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity

Publications (2)

Publication Number Publication Date
FR2112098A1 true FR2112098A1 (en) 1972-06-16
FR2112098B1 FR2112098B1 (en) 1974-04-12

Family

ID=9063664

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7039458A Granted FR2112098A1 (en) 1970-11-03 1970-11-03 Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity

Country Status (1)

Country Link
FR (1) FR2112098A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0654479A2 (en) * 1993-11-15 1995-05-24 Kureha Chemical Industry Co., Ltd. Esculetin derivatives and method for manufacture thereof, use thereof, and pharmaceutical composition

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0654479A2 (en) * 1993-11-15 1995-05-24 Kureha Chemical Industry Co., Ltd. Esculetin derivatives and method for manufacture thereof, use thereof, and pharmaceutical composition
EP0654479A3 (en) * 1993-11-15 1995-09-13 Kureha Chemical Ind Co Ltd Esculetin derivatives and method for manufacture thereof, use thereof, and pharmaceutical composition.
US5736522A (en) * 1993-11-15 1998-04-07 Kureha Chemical Industry Co., Ltd. Esculetin derivatives and method for manufacture thereof, use thereof, and pharmaceutical composition
CN1053193C (en) * 1993-11-15 2000-06-07 吴羽化学工业株式会社 Esculetin derivatives, process for manufacture and use thereof, and pharmaceutical composition

Also Published As

Publication number Publication date
FR2112098B1 (en) 1974-04-12

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Legal Events

Date Code Title Description
ST Notification of lapse