FR2081551A1 - Oxazolidinone derivs tranquillisers prepn - Google Patents

Oxazolidinone derivs tranquillisers prepn

Info

Publication number
FR2081551A1
FR2081551A1 FR7106815A FR7106815A FR2081551A1 FR 2081551 A1 FR2081551 A1 FR 2081551A1 FR 7106815 A FR7106815 A FR 7106815A FR 7106815 A FR7106815 A FR 7106815A FR 2081551 A1 FR2081551 A1 FR 2081551A1
Authority
FR
France
Prior art keywords
pref
max
tranquillisers
derivs
prepn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7106815A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of FR2081551A1 publication Critical patent/FR2081551A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Oxazolidinone derivs tranquillisers prepn Cpds of gen formula (I): (where R1 and R2 are same or different alkyl (pref. max. C6) or R1 + R2 + N form a heterocyclic radical (pref. 5-7 membered); A= straight or branched alkylene (pref. C2-6); X=aryl (pref. phenyl or naphthyl) opt. substd with one or more halogen, alkyl and alkoxy (max C5) acylamino (max C6) or alkylene (C3-4) and their acid-addn salts are sedatives anticonvulsives and beta-adrenergic blocks and are used in the treatment of Parkinsons' Disease and neurotic conditions. Pref. cpds are e.g. 3-beta-diethylaminoethyl-5-(napht-1(A) or 2- (B)yloxymethyl) oxasolidin-2-one.
FR7106815A 1970-02-27 1971-02-26 Oxazolidinone derivs tranquillisers prepn Withdrawn FR2081551A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB954770 1970-02-27

Publications (1)

Publication Number Publication Date
FR2081551A1 true FR2081551A1 (en) 1971-12-03

Family

ID=9874105

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7106815A Withdrawn FR2081551A1 (en) 1970-02-27 1971-02-26 Oxazolidinone derivs tranquillisers prepn

Country Status (5)

Country Link
BE (1) BE763575A (en)
DE (1) DE2109651A1 (en)
FR (1) FR2081551A1 (en)
NL (1) NL7102501A (en)
ZA (1) ZA71932B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029783A (en) * 1973-08-03 1977-06-14 Boehringer Mannheim G.M.B.H. N-substituted 1-amino-3-phenoxy-propan-2-ol compounds and therapeutic compositions containing them
FR2315925A1 (en) * 1975-07-04 1977-01-28 Nippon Chemiphar Co NEW 5-BENZYL-2-OXAZOLIDONE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION
DE2538424C2 (en) * 1975-08-29 1983-01-05 Nordmark-Werke Gmbh, 2000 Hamburg 4-substituted 5-phenyl-oxazolidone- (2) - compounds and a pharmaceutical preparation containing them
DE2644833A1 (en) * 1976-10-05 1978-04-20 Boehringer Sohn Ingelheim NEW 1-ARYLOXY-2-HYDROXY-3-ALKYLENE AMINOPROPANES AND METHOD FOR THE PRODUCTION THEREOF
JPWO2008120655A1 (en) * 2007-03-30 2010-07-15 株式会社医薬分子設計研究所 Oxazolidinone derivatives having type I 11β-hydroxysteroid dehydrogenase inhibitory activity

Also Published As

Publication number Publication date
BE763575A (en) 1971-08-26
DE2109651A1 (en) 1971-09-09
ZA71932B (en) 1971-10-27
NL7102501A (en) 1971-08-31

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Legal Events

Date Code Title Description
ST Notification of lapse