FR2077694A1 - Isopropylaminopropyl ethers of khellin-quinol - as coronary vasodilat and oxygen economisers - Google Patents

Isopropylaminopropyl ethers of khellin-quinol - as coronary vasodilat and oxygen economisers

Info

Publication number
FR2077694A1
FR2077694A1 FR7004180A FR7004180A FR2077694A1 FR 2077694 A1 FR2077694 A1 FR 2077694A1 FR 7004180 A FR7004180 A FR 7004180A FR 7004180 A FR7004180 A FR 7004180A FR 2077694 A1 FR2077694 A1 FR 2077694A1
Authority
FR
France
Prior art keywords
khellin
quinol
ethers
vasodilat
economisers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7004180A
Other languages
French (fr)
Other versions
FR2077694B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SOBIO LAB
Original Assignee
SOBIO LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SOBIO LAB filed Critical SOBIO LAB
Priority to FR7004180A priority Critical patent/FR2077694A1/en
Publication of FR2077694A1 publication Critical patent/FR2077694A1/en
Application granted granted Critical
Publication of FR2077694B1 publication Critical patent/FR2077694B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Basic ethers of khellin-quinol are of formula: Specific cpds. are the 2-hydroxy-3-isopropylamino-propyl ether and its hydrochloride, and the N-benzyl deriv. and its hydrochloride, citrate, maleate and tartrate. They are prepd. by reacting the 2, 3-epoxy-prop-1-yl ether of khellin-quinol with benzyl-isopropylamine to give I(R = benzyl), which in turn is hydrogenated to give I(R = H).
FR7004180A 1970-02-06 1970-02-06 Isopropylaminopropyl ethers of khellin-quinol - as coronary vasodilat and oxygen economisers Granted FR2077694A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7004180A FR2077694A1 (en) 1970-02-06 1970-02-06 Isopropylaminopropyl ethers of khellin-quinol - as coronary vasodilat and oxygen economisers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7004180A FR2077694A1 (en) 1970-02-06 1970-02-06 Isopropylaminopropyl ethers of khellin-quinol - as coronary vasodilat and oxygen economisers

Publications (2)

Publication Number Publication Date
FR2077694A1 true FR2077694A1 (en) 1971-11-05
FR2077694B1 FR2077694B1 (en) 1973-03-16

Family

ID=9050167

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7004180A Granted FR2077694A1 (en) 1970-02-06 1970-02-06 Isopropylaminopropyl ethers of khellin-quinol - as coronary vasodilat and oxygen economisers

Country Status (1)

Country Link
FR (1) FR2077694A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2232311A1 (en) * 1973-06-05 1975-01-03 Sobio Lab Antiarrhythmic khellin-quinol derivs. - comprising the t-butyl-amino-hydroxy-propyl and di-isopropyl-amino-ethyl ethers

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1067033B (en) * 1959-10-15 Chem pharmaz Fabrik Dr Hermann Thiemann GmbH Lunen (Westf ) Process for the preparation of basic substituted monoethers of 2-methyl 5 8-dioxy-4'5 6,7-furano chromons

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1067033B (en) * 1959-10-15 Chem pharmaz Fabrik Dr Hermann Thiemann GmbH Lunen (Westf ) Process for the preparation of basic substituted monoethers of 2-methyl 5 8-dioxy-4'5 6,7-furano chromons

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2232311A1 (en) * 1973-06-05 1975-01-03 Sobio Lab Antiarrhythmic khellin-quinol derivs. - comprising the t-butyl-amino-hydroxy-propyl and di-isopropyl-amino-ethyl ethers

Also Published As

Publication number Publication date
FR2077694B1 (en) 1973-03-16

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