FR2051485A1 - N-alkylpiperidyl (3) dehydrocholates with - choleretic properties - Google Patents

N-alkylpiperidyl (3) dehydrocholates with - choleretic properties

Info

Publication number
FR2051485A1
FR2051485A1 FR6916762A FR6916762A FR2051485A1 FR 2051485 A1 FR2051485 A1 FR 2051485A1 FR 6916762 A FR6916762 A FR 6916762A FR 6916762 A FR6916762 A FR 6916762A FR 2051485 A1 FR2051485 A1 FR 2051485A1
Authority
FR
France
Prior art keywords
dehydrocholates
alkylpiperidyl
choleretic
dehydrocholic acid
choleretic properties
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6916762A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RABOT ETS DAVID
Original Assignee
RABOT ETS DAVID
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RABOT ETS DAVID filed Critical RABOT ETS DAVID
Priority to FR6916762A priority Critical patent/FR2051485A1/en
Priority to DE19702024135 priority patent/DE2024135A1/de
Priority to AU15342/70A priority patent/AU1534270A/en
Priority to ZA703479A priority patent/ZA703479B/en
Publication of FR2051485A1 publication Critical patent/FR2051485A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

N-alkylpiperidyl(3) dehydrocholates with choleretic properties Esters R'COOC5H4NCH2R, (where R' denotes the dehydrocholic acid residue structure, and R = H, a 1-12C hydrocarbyl, alkenyl, cycloalkyl, aryl, or a heterocyclic ring, pref. substd.) are prepared from dehydrocholic acid and corresponding N-alkylpiperidine-3-ols, and are converted to salts with a wide range of mineral and aminoacids. The new derivs. are valuable drugs for the treatment of liver and gall disorders.
FR6916762A 1969-05-22 1969-05-22 N-alkylpiperidyl (3) dehydrocholates with - choleretic properties Withdrawn FR2051485A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR6916762A FR2051485A1 (en) 1969-05-22 1969-05-22 N-alkylpiperidyl (3) dehydrocholates with - choleretic properties
DE19702024135 DE2024135A1 (en) 1969-05-22 1970-05-16
AU15342/70A AU1534270A (en) 1969-05-22 1970-05-20 Novel aminoalcohol esters of triketo 3, 7, 12 cholanic acid and salts thereof
ZA703479A ZA703479B (en) 1969-05-22 1970-05-22 "novel dehydrocholic acid esters and certain of their salts"

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6916762A FR2051485A1 (en) 1969-05-22 1969-05-22 N-alkylpiperidyl (3) dehydrocholates with - choleretic properties

Publications (1)

Publication Number Publication Date
FR2051485A1 true FR2051485A1 (en) 1971-04-09

Family

ID=9034464

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6916762A Withdrawn FR2051485A1 (en) 1969-05-22 1969-05-22 N-alkylpiperidyl (3) dehydrocholates with - choleretic properties

Country Status (4)

Country Link
AU (1) AU1534270A (en)
DE (1) DE2024135A1 (en)
FR (1) FR2051485A1 (en)
ZA (1) ZA703479B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8034823B2 (en) * 2005-02-22 2011-10-11 Savvipharm Inc Method of increasing drug oral bioavailability and compositions of less toxic orotate salts

Also Published As

Publication number Publication date
ZA703479B (en) 1971-09-29
DE2024135A1 (en) 1970-12-17
AU1534270A (en) 1971-11-25

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Legal Events

Date Code Title Description
ST Notification of lapse