FR2024174B1 - - Google Patents

Info

Publication number: FR2024174B1
Authority: FR; France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

FR696940410A

Other versions

FR2024174A1 (fr

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck et Cie

Merck and Co Inc

Original Assignee

Merck et Cie

Merck and Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1968-11-25

Filing date

1969-11-24

Publication date

1973-07-13

1969-11-24 Application filed by Merck et Cie, Merck and Co Inc filed Critical Merck et Cie

1970-08-28 Publication of FR2024174A1 publication Critical patent/FR2024174A1/fr

1973-07-13 Application granted granted Critical

1973-07-13 Publication of FR2024174B1 publication Critical patent/FR2024174B1/fr

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton

FR696940410A 1968-11-25 1969-11-24 Expired FR2024174B1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US77881968A	1968-11-25	1968-11-25

Publications (2)

Publication Number	Publication Date
FR2024174A1 FR2024174A1 (fr)	1970-08-28
FR2024174B1 true FR2024174B1 (fr)	1973-07-13

Family

ID=25114484

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR696940410A Expired FR2024174B1 (fr)	1968-11-25	1969-11-24

Country Status (5)

Country	Link
US (1)	US3668241A (fr)
DE (1)	DE1958918A1 (fr)
FR (1)	FR2024174B1 (fr)
GB (1)	GB1254907A (fr)
NL (1)	NL6916777A (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE791201A (fr) *	1971-11-12	1973-05-10	Merck & Co Inc	Indanyloxytetrazoles
US3976686A (en) *	1972-10-13	1976-08-24	Merck & Co., Inc.	[1-Oxo-2,3-hydrocarbylene-5-indanyloxy(or thio)]alkanoic acids
US3984465A (en) *	1972-10-13	1976-10-05	Merck & Co., Inc.	1-Oxo-2,2-disubstituted-5-indanyloxy(or thio)alkanoic acids
US4081554A (en) *	1972-10-13	1978-03-28	Merck & Co., Inc.	1-oxo-2,2-disubstituted-5-indanyloxy(or thio)alkano acids
US4182764A (en) *	1973-10-11	1980-01-08	Merck & Co., Inc.	Tetrazole derivatives of [1-oxo-2-aryl or thienyl-2-substituted-5-indanyloxy(or thio)]alkanoic acids
NL187854C (nl) *	1973-10-11	1992-02-03	Merck & Co Inc	Werkwijze ter bereiding van farmaceutische preparaten met diuretische en saluretische werking, alsmede werkwijze ter bereiding van voor toepassing daarbij geschikte op plaats 2 gesubstitueerde 1-oxo-5-indanyloxy-(of -thio-)-alkaanzuren.
US3976681A (en) *	1973-10-12	1976-08-24	Merck & Co., Inc.	[1,3-Dioxo-2-substituted and 2,2-disubstituted- indanyloxy (or thio] alkanoic acids
US4006180A (en) *	1973-10-12	1977-02-01	Merck & Co., Inc.	[1,3-Dihydroxy-2-substituted and 2,2-disubstituted-indanyloxy(or thio)]alkanoic acids
US4012524A (en) *	1973-10-12	1977-03-15	Merck & Co., Inc.	[1-Hydroxy-5-indanyloxy (or thio)]-alkanoic acids
US4003927A (en) *	1973-10-12	1977-01-18	Merck & Co., Inc.	(1-Oxo-7,8-disubstituted-1,2,3,4-tetrahydro-6-naphthyloxy)- and (3,4-disubstituted-5-oxo-6,7,8,9-tetrahydro-5H-benzocycloheptene-2-yloxy) acetic acids and derivatives
US3929872A (en) *	1973-10-12	1975-12-30	Merck & Co Inc	Indanacetic acid compounds
US3981911A (en) *	1974-02-15	1976-09-21	Merck & Co., Inc.	Process for preparing (1-oxo-2-cyclopentyl-2-methyl-6,7-dichloro-5-indanyloxy)acetic acid
PL98342B1 (pl) *	1974-07-30	1978-04-29		Sposob wytwarzania kwasu 1-keto-2-arylo-/lub tienylo/-2-podstawionego-indanyloksy-/lub tio/-5-alkanokarboksylowego
US4281017A (en) *	1978-09-16	1981-07-28	Lilly Industries Limited	Pharmaceutically active indane derivatives
US4389417A (en) *	1980-09-05	1983-06-21	Merck & Co., Inc.	Treatment of gray matter edema
US4463208A (en) *	1981-12-30	1984-07-31	Merck & Co., Inc.	Treatment of gray matter edema
US5001255A (en) *	1984-12-04	1991-03-19	Sandoz Pharm. Corp.	Idene analogs of mevalonolactone and derivatives thereof
US6858615B2 (en) *	2002-02-19	2005-02-22	Parion Sciences, Inc.	Phenyl guanidine sodium channel blockers
US6858614B2 (en)	2002-02-19	2005-02-22	Parion Sciences, Inc.	Phenolic guanidine sodium channel blockers
FR2849849B1 (fr) *	2003-01-13	2006-08-04	Merck Sante Sas	Nouveaux acides carboxyliques et derives pour le traitement et la prevention du diabete et des dyslipemies
US6903105B2 (en)	2003-02-19	2005-06-07	Parion Sciences, Inc.	Sodium channel blockers
US20050090505A1 (en) *	2003-08-18	2005-04-28	Johnson Michael R.	Methods of reducing risk of infection from pathogens
US7745442B2 (en)	2003-08-20	2010-06-29	Parion Sciences, Inc.	Methods of reducing risk of infection from pathogens
AR086745A1 (es)	2011-06-27	2014-01-22	Parion Sciences Inc	3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
HUE032891T2 (hu)	2012-12-17	2017-11-28	Parion Sciences Inc	Klórpirazin-karboxamid-származékok nem kielégítõ nyálkahártya-hidratáció által elõsegített megbetegedések kezelésére
US9029382B2 (en)	2012-12-17	2015-05-12	Parion Sciences, Inc.	3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds
US9102633B2 (en)	2013-12-13	2015-08-11	Parion Sciences, Inc.	Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

1968
- 1968-11-25 US US778819A patent/US3668241A/en not_active Expired - Lifetime
1969
- 1969-11-06 NL NL6916777A patent/NL6916777A/xx unknown
- 1969-11-21 GB GB57071/69A patent/GB1254907A/en not_active Expired
- 1969-11-24 DE DE19691958918 patent/DE1958918A1/de active Pending
- 1969-11-24 FR FR696940410A patent/FR2024174B1/fr not_active Expired

Also Published As

Publication number	Publication date
GB1254907A (en)	1971-11-24
NL6916777A (fr)	1970-05-27
DE1958918A1 (de)	1970-05-27
US3668241A (en)	1972-06-06
FR2024174A1 (fr)	1970-08-28

Legal Events

Date	Code	Title	Description
1980-10-17	ST	Notification of lapse

Publication	Publication Date	Title
FR2024193A1 (fr)	1970-08-28
AU428130B2 (fr)	1972-09-14
AU2374870A (fr)	1972-06-29
AU5184069A (fr)	1970-07-17
AU6168869A (fr)	1971-04-08
AU6171569A (fr)	1971-04-08
AU429879B2 (fr)	1972-11-09
AU416157B2 (fr)	1971-08-23
AU2581067A (fr)	1970-02-19
AU4811568A (fr)	1974-08-01
AU421558B1 (fr)	1970-01-29
AU4744468A (fr)	1970-06-18
AU3789668A (fr)	1968-06-20
AU3224368A (fr)	1969-07-17
AU2580267A (fr)	1970-02-05
AU479393A (fr)	1974-02-07
BE642636A (fr)
AU4558658A (fr)	1970-05-07
AU463027A (fr)	1971-03-04
AU4464266A (fr)	1970-04-16
BE726287A (fr)	1969-05-29
AU479894A (fr)	1973-08-30
AU4270368A (fr)	1970-03-05
AU4224469A (fr)	1970-02-26
AU3083868A (fr)	1969-10-30