FR2011940A1 - Compns contng cysteine cysteamine derivs for acne - Google Patents

Compns contng cysteine cysteamine derivs for acne

Info

Publication number
FR2011940A1
FR2011940A1 FR6919792A FR6919792A FR2011940A1 FR 2011940 A1 FR2011940 A1 FR 2011940A1 FR 6919792 A FR6919792 A FR 6919792A FR 6919792 A FR6919792 A FR 6919792A FR 2011940 A1 FR2011940 A1 FR 2011940A1
Authority
FR
France
Prior art keywords
free amino
contng
lower alkyl
derivs
compns
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR6919792A
Other languages
French (fr)
Other versions
FR2011940B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Publication of FR2011940A1 publication Critical patent/FR2011940A1/en
Application granted granted Critical
Publication of FR2011940B1 publication Critical patent/FR2011940B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Cosmetic compns. contng. S-substd. derivs. of cysteine and cysteamine, (I), (II), (III) and (IV) where R=Ph3C, Ph2CH, PhCH2, HOOC-(CH2)n; n=1-4 (pref. 1 or 2) where R1,2=H or lower alkyl; n=0 or 1 R3=-(CH2)p-R4; p=0-2 R4=Ph, -CHOHCH2N Me3.Cl, COOR5 (R5=H, lower alkyl), t-Bu, CPh3, CH2NH2, CH(NH2)COOR5, 2-thienyl 2-N-oxypyridyl where R=up to 20C hydrocarbyl, opt. contng. heteroatoms and 1 or more OH gps. as well as the salts, esters and N-acyl/sulphonyl derivs. of (I)-(III). where R1,R2=H or lower alkyl; n=0 or 1 R3=-(CH2)p-R6; p=0-2 R6=Ph, COOR (R=lower alkyl), t-Bu, CPh3, CH(NHR7)COOR8 (R7=H, acyl, sulphonyl; R8=lower alkyl, or H when R7=H), CH2NHR7, 2-thienyl, 2-pyridyl, 2-N-oxypyridyl, up to 20C hydrocarbyl, opt. contng. hetero atoms and 1 or more OH gps. R4=H when R5=(CH2)mCOOH (m=1-5) and y=1, x=1 if R3 contains no free amino gp., y=2, x=1 if R3 contains a free amino gp. R4=acyl or sulphonyl when R5=Ph3C, Ph2CH, PhCH2 and y=1, x=1 if R3 contains no free amino gp., y=2, x=1 if R3 contains a free amino gp.; (CH2)mCOOH and y=1, x=1 if R3 contains a free amino gp. y=1, x=2 if R3 contains no free amino gp. Also when the active cpd. contains a free COOH this may be complexed with a bactericidal quaternary ammonium cation. Over 40 cpds. For treating acne.
FR6919792A 1968-06-14 1969-06-13 Compns contng cysteine cysteamine derivs for acne Granted FR2011940A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73696068A 1968-06-14 1968-06-14

Publications (2)

Publication Number Publication Date
FR2011940A1 true FR2011940A1 (en) 1970-03-13
FR2011940B1 FR2011940B1 (en) 1974-08-09

Family

ID=24962038

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6919792A Granted FR2011940A1 (en) 1968-06-14 1969-06-13 Compns contng cysteine cysteamine derivs for acne

Country Status (8)

Country Link
JP (1) JPS5022096B1 (en)
BE (1) BE733993A (en)
CA (1) CA930669A (en)
CH (1) CH534515A (en)
DE (1) DE1930023A1 (en)
ES (1) ES368323A1 (en)
FR (1) FR2011940A1 (en)
NL (1) NL6909079A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2462159A1 (en) * 1979-08-02 1981-02-13 Oreal Strengthening and revitalising brittle finger nails - using an inorganic or organic salt of benzyl-2-thio:ethylamine
US4323553A (en) * 1979-05-03 1982-04-06 L'oreal Composition for strengthening and revitalizing brittle or damaged nails containing a salt of 2-benzylthio ethylamine
FR2740340A1 (en) * 1995-10-30 1997-04-30 Oreal USE OF CARBOXYLIC ACIDS WITH SULFUR FUNCTION TO PROMOTE SKIN DESQUACATION OR TO STIMULATE EPIDERMAL RENEWAL

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU63057A1 (en) * 1971-04-23 1972-12-11 Oreal
LU76148A1 (en) * 1976-11-08 1978-07-10
ITMI20020510A1 (en) * 2002-03-11 2003-09-11 Ghisalberti Carlo TOPICAL COMPOSITIONS CONTAINING L-CISTEIN DERIVATIVES
CN115501125A (en) * 2022-10-20 2022-12-23 澳门科技大学 H for repairing skin lesions 2 S donor gel and H 2 Preparation method of S donor gel

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE658449A (en) * 1964-01-29 1965-07-19
FR1505874A (en) * 1965-12-22 1967-12-15 Oreal New hair product
BE716891A (en) * 1967-06-21 1968-12-20
BE718559A (en) * 1967-07-26 1969-01-27

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE658449A (en) * 1964-01-29 1965-07-19
FR1505874A (en) * 1965-12-22 1967-12-15 Oreal New hair product
BE716891A (en) * 1967-06-21 1968-12-20
BE718559A (en) * 1967-07-26 1969-01-27

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4323553A (en) * 1979-05-03 1982-04-06 L'oreal Composition for strengthening and revitalizing brittle or damaged nails containing a salt of 2-benzylthio ethylamine
FR2462159A1 (en) * 1979-08-02 1981-02-13 Oreal Strengthening and revitalising brittle finger nails - using an inorganic or organic salt of benzyl-2-thio:ethylamine
FR2740340A1 (en) * 1995-10-30 1997-04-30 Oreal USE OF CARBOXYLIC ACIDS WITH SULFUR FUNCTION TO PROMOTE SKIN DESQUACATION OR TO STIMULATE EPIDERMAL RENEWAL
WO1997016165A1 (en) * 1995-10-30 1997-05-09 L'oreal Use of carboxylic acids having a sulphur function for promoting skin exfoliation or stimulating epidermal regeneration

Also Published As

Publication number Publication date
FR2011940B1 (en) 1974-08-09
CH534515A (en) 1973-03-15
JPS5022096B1 (en) 1975-07-28
ES368323A1 (en) 1971-06-16
BE733993A (en) 1969-12-03
NL6909079A (en) 1969-12-16
CA930669A (en) 1973-07-24
DE1930023A1 (en) 1970-01-15

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