FR1600908A - Hypocholesterolaemic and anorexigenic - phenoxy alkanoylaralkylamines - Google Patents

Hypocholesterolaemic and anorexigenic - phenoxy alkanoylaralkylamines

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Publication number
FR1600908A
FR1600908A FR1600908DA FR1600908A FR 1600908 A FR1600908 A FR 1600908A FR 1600908D A FR1600908D A FR 1600908DA FR 1600908 A FR1600908 A FR 1600908A
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FR
France
Prior art keywords
phenyl
opt
hypocholesterolaemic
anorexigenic
alkyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
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French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Application granted granted Critical
Publication of FR1600908A publication Critical patent/FR1600908A/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Hypocholesterolaemic and anorexigenic phenoxyalkanoylaralylamines. Cpds. of formula (I): (where X is one or more alkyl, alkenyl, CF3, cycloalkyl aryl, aralkyl, aralkenyl, halogen, alkoxy, alkylthio, aryloxy, aralkoxy, arylthio, or aralkylthio, X can also be CH:CHCH:CH; Y is 1-18C divalent hydrocarbon opt. contg. a CO, OH, phenyl, alkyl-, aralkyl-, aryl-, acyl-, alkoxy-, or halo-phenyl, Z is 1-5C satd. divalent hydrocarbon, X' is opt. halogen, low alkyl, or CF3, R is H or low alkyl) may be prepd. by reacting an active deriv. of a phenoxyalkanoic acid with an appropriate aralkylamine opt. in the presence of a base. A typical cpd. is N- 2-(4-chlorophenoxy)-2-methylpropionyl -1-phenyl-2-aminopropane.
FR1600908D 1968-11-14 1968-11-14 Hypocholesterolaemic and anorexigenic - phenoxy alkanoylaralkylamines Expired FR1600908A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR173820 1968-11-14

Publications (1)

Publication Number Publication Date
FR1600908A true FR1600908A (en) 1970-08-03

Family

ID=8656891

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1600908D Expired FR1600908A (en) 1968-11-14 1968-11-14 Hypocholesterolaemic and anorexigenic - phenoxy alkanoylaralkylamines

Country Status (1)

Country Link
FR (1) FR1600908A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2514757A1 (en) * 1981-10-20 1983-04-22 Ube Industries PHENOXYALKYLAMIDES, PREPARATION THEREOF, HERBICIDAL COMPOSITIONS CONTAINING THE SAME, AND THEIR USE IN DESTRUCTION OF WEEDS
EP1768954A2 (en) * 2004-06-24 2007-04-04 Incyte Corporation 2-methylpropanamides and their use as pharmaceuticals
US8071624B2 (en) 2004-06-24 2011-12-06 Incyte Corporation N-substituted piperidines and their use as pharmaceuticals

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2514757A1 (en) * 1981-10-20 1983-04-22 Ube Industries PHENOXYALKYLAMIDES, PREPARATION THEREOF, HERBICIDAL COMPOSITIONS CONTAINING THE SAME, AND THEIR USE IN DESTRUCTION OF WEEDS
EP1768954A2 (en) * 2004-06-24 2007-04-04 Incyte Corporation 2-methylpropanamides and their use as pharmaceuticals
EP1768954A4 (en) * 2004-06-24 2008-05-28 Incyte Corp 2-methylpropanamides and their use as pharmaceuticals
US7687665B2 (en) 2004-06-24 2010-03-30 Incyte Corporation 2-methylprop anamides and their use as pharmaceuticals
US8071624B2 (en) 2004-06-24 2011-12-06 Incyte Corporation N-substituted piperidines and their use as pharmaceuticals
US8288417B2 (en) 2004-06-24 2012-10-16 Incyte Corporation N-substituted piperidines and their use as pharmaceuticals

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