FR14C0044I2 - 3-(2-OXO-1,3']BIPYRROLIDINYL-3-YLIDENEMETHYL)-CEPHEMES DERIVATIVES - Google Patents

3-(2-OXO-1,3']BIPYRROLIDINYL-3-YLIDENEMETHYL)-CEPHEMES DERIVATIVES

Info

Publication number
FR14C0044I2
FR14C0044I2 FR14C0044C FR14C0044C FR14C0044I2 FR 14C0044 I2 FR14C0044 I2 FR 14C0044I2 FR 14C0044 C FR14C0044 C FR 14C0044C FR 14C0044 C FR14C0044 C FR 14C0044C FR 14C0044 I2 FR14C0044 I2 FR 14C0044I2
Authority
FR
France
Prior art keywords
cephemes
bipyrrolidinyl
ylidenemethyl
oxo
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR14C0044C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Basilea Pharmaceutica AG
Original Assignee
Basilea Pharmaceutica AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica AG filed Critical Basilea Pharmaceutica AG
Publication of FR14C0044I1 publication Critical patent/FR14C0044I1/fr
Application granted granted Critical
Publication of FR14C0044I2 publication Critical patent/FR14C0044I2/en
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48—Methylene radicals, substituted by hetero rings
    • C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR14C0044C 1998-06-15 2014-06-11 3-(2-OXO-1,3']BIPYRROLIDINYL-3-YLIDENEMETHYL)-CEPHEMES DERIVATIVES Active FR14C0044I2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP98110888 1998-06-15
EP98117099 1998-09-10
EP99927894A EP1087980B1 (en) 1998-06-15 1999-06-07 Derivatives of 3-(2-oxo- 1,3']bipyrrolidinyl-3-ylidenemethyl)-cephems
PCT/EP1999/003907 WO1999065920A1 (en) 1998-06-15 1999-06-07 Derivatives of 3-(2-oxo-[1,3']bipyrrolidinyl-3-ylidenemethyl)-cephems

Publications (2)

Publication Number Publication Date
FR14C0044I1 FR14C0044I1 (en) 2014-07-18
FR14C0044I2 true FR14C0044I2 (en) 2015-02-20

Family

ID=26149347

Family Applications (1)

Application Number Title Priority Date Filing Date
FR14C0044C Active FR14C0044I2 (en) 1998-06-15 2014-06-11 3-(2-OXO-1,3']BIPYRROLIDINYL-3-YLIDENEMETHYL)-CEPHEMES DERIVATIVES

Country Status (28)

Country Link
EP (1) EP1087980B1 (en)
JP (1) JP3872955B2 (en)
KR (1) KR100411915B1 (en)
CN (1) CN1136222C (en)
AR (1) AR018675A1 (en)
AT (1) ATE231871T1 (en)
AU (1) AU754732B2 (en)
BE (1) BE2014C034I2 (en)
BR (2) BRPI9911178C1 (en)
CA (1) CA2334568C (en)
CO (1) CO5080758A1 (en)
DE (1) DE69905162T2 (en)
DK (1) DK1087980T3 (en)
ES (1) ES2190222T3 (en)
FR (1) FR14C0044I2 (en)
GT (1) GT199900084A (en)
HU (1) HUP0105426A3 (en)
ID (1) ID27686A (en)
IL (1) IL139872A0 (en)
LU (1) LU92564I2 (en)
MA (1) MA26650A1 (en)
NO (1) NO20006350D0 (en)
PA (1) PA8475701A1 (en)
PE (1) PE20000645A1 (en)
PL (1) PL344994A1 (en)
SV (1) SV1999000075A (en)
TN (1) TNSN99114A1 (en)
WO (1) WO1999065920A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6267100A (en) * 1999-07-07 2001-01-30 F. Hoffmann-La Roche Ag Vinylpyrrolidinone derivatives with substituted thiazole ring
DK1148140T3 (en) 2000-04-19 2007-01-08 Basilea Pharmaceutica Ag Process for the preparation of D-asparagine derivatives
US6504025B2 (en) * 2000-05-24 2003-01-07 Basilea Pharmaceutica Ag Process for the preparation of vinyl-pyrrolidinone cephalosporin derivatives
JP5230934B2 (en) * 2003-03-27 2013-07-10 バジリア ファルマスーチカ アーゲー Crystalline cephalosporin
EP1656930A1 (en) * 2004-11-10 2006-05-17 Basilea Pharmaceutica AG Stabilized freeze-dried formulation for cephalosporin derivatives
AR071318A1 (en) 2008-04-15 2010-06-09 Basilea Pharmaceutica Ag BENZHIDRIL ESTER OF THE ACID (6R, 7R) -7- {2- (5-AMINO- [1,2,4] TIADIAZOL-3-IL) -2 - [(Z) -TRITILOXIIMINO] -ACETILAMINO} -3- [ (R) -1'-TERC-BUTOXICARBONIL-2-OXO- [1,3 '] BIPIRROLIDINIL- (3E) -ILIDENOMETIL] -8-OXO-5-TIA-1-AZA-BICICLO [4.2.0] OCT- 2-ENO-2-CARBOXILICO CRISTALINO; YOUR ELABORATION AND USE
WO2010072672A1 (en) 2008-12-24 2010-07-01 Basilea Pharmaceutica Ag New crystal polymorphs of ceftobiprole
ES2565952T3 (en) * 2009-05-25 2016-04-07 Sandoz Ag Method for the production of ceftobiprol medocaril
BR112012028678A2 (en) 2010-05-10 2015-09-15 Basilea Pharmaceutica Internat Ltd oxidation process for preparing 3-formyl cefem derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2281090T3 (en) * 1996-11-06 2007-09-16 Basilea Pharmaceutica Ag DERIVATIVES OF VINILPIRROLIDONA-CEFALOSPORINA.
TW415949B (en) * 1996-12-19 2000-12-21 Hoffmann La Roche Vinyl pyrrolidine cephalosporin derivatives with basic substituents

Also Published As

Publication number Publication date
EP1087980B1 (en) 2003-01-29
JP3872955B2 (en) 2007-01-24
MA26650A1 (en) 2004-12-20
AU4508199A (en) 2000-01-05
DE69905162D1 (en) 2003-03-06
DE69905162T2 (en) 2003-12-24
HUP0105426A3 (en) 2002-12-28
PL344994A1 (en) 2001-11-19
ATE231871T1 (en) 2003-02-15
DK1087980T3 (en) 2003-05-26
CA2334568C (en) 2009-02-24
JP2002518401A (en) 2002-06-25
ID27686A (en) 2001-04-19
BRPI9911178C1 (en) 2021-05-25
BRPI9911178B8 (en) 2017-03-07
SV1999000075A (en) 2000-05-02
KR100411915B1 (en) 2003-12-18
BR9911178B1 (en) 2013-10-29
NO20006350L (en) 2000-12-13
TNSN99114A1 (en) 2005-11-10
BE2014C034I2 (en) 2018-08-24
PA8475701A1 (en) 2000-09-29
PE20000645A1 (en) 2000-07-26
CA2334568A1 (en) 1999-12-23
ES2190222T3 (en) 2003-07-16
NO20006350D0 (en) 2000-12-13
EP1087980A1 (en) 2001-04-04
AR018675A1 (en) 2001-11-28
IL139872A0 (en) 2002-02-10
GT199900084A (en) 2000-12-05
KR20010052866A (en) 2001-06-25
LU92564I2 (en) 2014-12-01
CN1305484A (en) 2001-07-25
HUP0105426A2 (en) 2002-05-29
BR9911178A (en) 2001-03-13
CN1136222C (en) 2004-01-28
WO1999065920A1 (en) 1999-12-23
CO5080758A1 (en) 2001-09-25
AU754732B2 (en) 2002-11-21
FR14C0044I1 (en) 2014-07-18

Similar Documents

Publication Publication Date Title
ATE435861T1 (en) 12,13-CYCLOPROPANE-EPOTHILONE DERIVATIVES
FR14C0044I2 (en) 3-(2-OXO-1,3']BIPYRROLIDINYL-3-YLIDENEMETHYL)-CEPHEMES DERIVATIVES
DE69907964D1 (en) 1,2-FELLENED CHINOLINE DERIVATIVES
MA26831A1 (en) BENZODIAZEPINE DERIVATIVES. "
MA26816A1 (en) AMINO-TRIAZOLOPYRIDINE DERIVATIVES
DE69716468D1 (en) 2- (purin-9 -) - tetrahydrofuran-3,4-DIOL DERIVATIVES
ATE340176T1 (en) SUBSTITUTED 6,5-HETEROBICYCLIC DERIVATIVES
DK1000048T3 (en) Substituted 1,2,3,4-tetrahydronaphthalane derivatives
ATE231847T1 (en) SUBSTITUTED 1,2,3,4-TETRAHYDRONAPHTHALINE DERIVATIVES
DE69821009D1 (en) 6,9-BRIDGED ERYTHROMYCIN DERIVATIVES
PT921125E (en) DERIVATIVES OF 1,38-TRIAZA-ESPIRO 4,5 DECAN-4-ONA
ATE239750T1 (en) 6,11-BRIDGED ERYTHROMYCIN DERIVATIVES
MA26503A1 (en) 5'-DESOXY-CYTIDINE DERIVATIVES.
NO20003825L (en) 1,3,4 - oxadiazolone derivatives
PT1060183E (en) 5'-DESOXICITIDIN DERIVATIVES
PT1129079E (en) TRIAZINE DERIVATIVES 2,4-DISSUBSTITUIDOS
ATE243218T1 (en) 2''-DEOXYHYGROMYCIN DERIVATIVES
BR9701404A (en) 1,25-dihydroxy-16,22,23-trisdehydro-cholecal-ciferol derivatives
NO20015397L (en) 1,5-Benzodiazepine derivatives
ES1041880Y (en) PICADOR'S PUYA
FI980405A0 (en) Industriellt, kontinuerligt foerfarande Foer framstaellning av "gravkalk"
BR1100649A (en) Dibenzo suberane 10,11-methane derivatives
MA26495A1 (en) EXOMETHYLENE DERIVATIVES