FR10C0024I2 - Liquid formulations containing a gonadotropin - Google Patents

Liquid formulations containing a gonadotropin

Info

Publication number
FR10C0024I2
FR10C0024I2 FR10C0024C FR10C0024C FR10C0024I2 FR 10C0024 I2 FR10C0024 I2 FR 10C0024I2 FR 10C0024 C FR10C0024 C FR 10C0024C FR 10C0024 C FR10C0024 C FR 10C0024C FR 10C0024 I2 FR10C0024 I2 FR 10C0024I2
Authority
FR
France
Prior art keywords
gonadotropin
formulations containing
liquid formulations
liquid
formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR10C0024C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Organon NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon NV filed Critical Organon NV
Publication of FR10C0024I1 publication Critical patent/FR10C0024I1/fr
Application granted granted Critical
Publication of FR10C0024I2 publication Critical patent/FR10C0024I2/en
Active legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
FR10C0024C 1997-01-15 2010-04-16 Liquid formulations containing a gonadotropin Active FR10C0024I2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97200099 1997-01-15
EP98200068A EP0853945B1 (en) 1997-01-15 1998-01-13 Liquid gonadotropin containing formulations

Publications (2)

Publication Number Publication Date
FR10C0024I1 FR10C0024I1 (en) 2010-05-21
FR10C0024I2 true FR10C0024I2 (en) 2011-04-01

Family

ID=8227932

Family Applications (1)

Application Number Title Priority Date Filing Date
FR10C0024C Active FR10C0024I2 (en) 1997-01-15 2010-04-16 Liquid formulations containing a gonadotropin

Country Status (30)

Country Link
US (1) US5929028A (en)
EP (2) EP0853945B1 (en)
JP (1) JP4353549B2 (en)
KR (1) KR100498531B1 (en)
CN (1) CN1165341C (en)
AR (1) AR011410A1 (en)
AT (1) ATE237348T1 (en)
AU (1) AU736339B2 (en)
BR (1) BR9800323B1 (en)
CA (1) CA2226803A1 (en)
CZ (1) CZ297419B6 (en)
DE (2) DE122010000011I1 (en)
DK (1) DK0853945T3 (en)
ES (1) ES2196474T3 (en)
FR (1) FR10C0024I2 (en)
HK (1) HK1010150A1 (en)
HU (1) HU227154B1 (en)
ID (1) ID19499A (en)
IL (1) IL122732A0 (en)
LU (1) LU91655I2 (en)
MX (1) MX9800438A (en)
NO (3) NO322509B1 (en)
NZ (1) NZ329572A (en)
PL (1) PL190103B1 (en)
PT (1) PT853945E (en)
RU (1) RU2203086C2 (en)
SA (1) SA98181124B1 (en)
TR (1) TR199800062A2 (en)
TW (1) TW518235B (en)
ZA (1) ZA9883B (en)

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JP4719357B2 (en) * 1998-07-23 2011-07-06 アレス トレイディング ソシエテ アノニム Formulations, products and methods of FSH and FSH variants
US20030166525A1 (en) 1998-07-23 2003-09-04 Hoffmann James Arthur FSH Formulation
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US20030104996A1 (en) * 2001-08-30 2003-06-05 Tiansheng Li L-methionine as a stabilizer for NESP/EPO in HSA-free formulations
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DE602004030546D1 (en) 2003-03-04 2011-01-27 Aspenbio Pharma Inc LH for use in maintaining one or more pregnancies by inducing the formation of the secondary corpus luteum.
WO2004087213A1 (en) * 2003-04-02 2004-10-14 Ares Trading S.A. Liquid pharmaceutical formulations of fsh and lh together with a non-ionic surfactant
US20040248784A1 (en) * 2003-06-03 2004-12-09 Marco Filicori Unitary combinations of FSH and hCG
PT1638595E (en) * 2003-06-20 2013-04-26 Ares Trading Sa Freeze-dried fsh / lh formulations
JP4412989B2 (en) * 2003-12-15 2010-02-10 株式会社日立製作所 Data processing system having a plurality of storage systems
KR100587535B1 (en) * 2004-02-04 2006-06-08 충남대학교산학협력단 A Recombinant hFSH Gene, and An Expression Vector Containing Thereof
TWI369401B (en) * 2005-07-05 2012-08-01 Ares Trading Sa Serum-free culture medium for the production of recombinant gonadotropins
KR101105871B1 (en) * 2005-09-27 2012-01-16 주식회사 엘지생명과학 hFSF Aqueous Formulation
US8168206B1 (en) 2005-10-06 2012-05-01 Allergan, Inc. Animal protein-free pharmaceutical compositions
US8137677B2 (en) * 2005-10-06 2012-03-20 Allergan, Inc. Non-protein stabilized clostridial toxin pharmaceutical compositions
WO2007056851A1 (en) * 2005-11-17 2007-05-24 Mount Sinai Hospital Compositions and methods for enhancing ovulation inducing agents
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US8946155B2 (en) 2006-02-03 2015-02-03 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US20140113860A1 (en) 2006-02-03 2014-04-24 Prolor Biotech Ltd. Long-acting polypeptides and methods of producing and administering same
US10351615B2 (en) 2006-02-03 2019-07-16 Opko Biologics Ltd. Methods of treatment with long-acting growth hormone
US9249407B2 (en) 2006-02-03 2016-02-02 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
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US9458444B2 (en) 2006-02-03 2016-10-04 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
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US10221228B2 (en) 2006-02-03 2019-03-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
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KR20080106636A (en) * 2007-06-04 2008-12-09 동아제약주식회사 Injectable ready to use solutions comprising human chorionic gonadotropin
AU2008269086B2 (en) * 2007-06-25 2014-06-12 Amgen Inc. Compositions of specific binding agents to hepatocyte growth factor
PT2170942E (en) 2007-06-28 2013-10-22 Biogenerix Ag Fsh producing cell clone
MY153976A (en) * 2007-11-01 2015-04-30 Merck Serono Sa Lh liquid formulations
NZ586588A (en) * 2008-02-08 2012-10-26 Biogenerix Ag Formulation of ( follice stimulating hormone) fsh and varients with benzalkonium chloride and benzyl alcohol
TWI488640B (en) * 2008-04-16 2015-06-21 Ferring Int Ct Sa Pharmaceutical preparation
CN101347613B (en) * 2008-09-17 2011-10-26 上海天伟生物制药有限公司 Composition of glucoprotein containing nearly no subunit and preparation method thereof
CN102309745B (en) * 2008-09-17 2013-05-08 上海天伟生物制药有限公司 Glycoprotein composition which almost does not contain subunit
EP2366401B1 (en) 2008-11-04 2015-07-15 ASKA Pharmaceutical Co., Ltd. Aqueous composition containing follicle-stimulating hormone
US9663778B2 (en) 2009-07-09 2017-05-30 OPKO Biologies Ltd. Long-acting coagulation factors and methods of producing same
TWI532495B (en) * 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 Pharmaceutical preparation
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EP2417982A1 (en) 2010-07-30 2012-02-15 Ferring B.V. Stabilization of gonadotropins
WO2012127501A2 (en) * 2011-03-11 2012-09-27 Sanzyme Limited Composition for improving endometrial thickness during ovarian stimulation
WO2012127500A2 (en) * 2011-03-11 2012-09-27 Sanzyme Limited Composition for spermatogenesis
JP6087338B2 (en) 2011-03-31 2017-03-01 フェリング ベスローテン フェンノートシャップ Pharmaceutical formulation
US20120265129A1 (en) 2011-04-15 2012-10-18 Neuralight Hd, Llc Methods for Chronic Pain Management and Treatment using HCG
US8680086B2 (en) 2011-04-15 2014-03-25 Neuralight Hd, Llc Methods for chronic pain management and treatment using HCG
US9353172B2 (en) 2011-07-18 2016-05-31 Arts Biologics A/S Long acting biologically active luteinizing hormone (LH) compound
JO3092B1 (en) 2011-08-08 2017-03-15 Ferring Bv Composition for controlled ovarian stimulation
CN104487082A (en) 2012-04-19 2015-04-01 奥普科生物制品有限公司 Long-acting oxyntomodulin variants and methods of producing same
MX2015004940A (en) 2012-10-18 2015-12-09 Neuralight Hd Llc Treatment of depression and ptsd.
BR122020018510B1 (en) 2012-11-20 2023-03-14 Opko Biologics Ltd METHOD FOR INCREMENTALLY INCREASE THE HYDRODYNAMIC SIZE OF AN ACTIVATED COAGULATION FACTOR VIIA
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Also Published As

Publication number Publication date
PT853945E (en) 2003-08-29
CN1191139A (en) 1998-08-26
EP0853945B1 (en) 2003-04-16
HUP9800056A2 (en) 1998-08-28
JPH10203997A (en) 1998-08-04
ZA9883B (en) 1998-07-08
LU91655I2 (en) 2010-04-26
NO980177D0 (en) 1998-01-14
HK1010150A1 (en) 1999-06-17
AR011410A1 (en) 2000-08-16
CA2226803A1 (en) 1998-07-15
TW518235B (en) 2003-01-21
CZ13598A3 (en) 1998-08-12
CN1165341C (en) 2004-09-08
ID19499A (en) 1998-07-16
IL122732A0 (en) 1998-08-16
AU5205998A (en) 1998-07-23
TR199800062A2 (en) 1998-08-21
NO322509B1 (en) 2006-10-16
NO980177L (en) 1998-07-16
BR9800323A (en) 1999-06-29
ES2196474T3 (en) 2003-12-16
AU736339B2 (en) 2001-07-26
ATE237348T1 (en) 2003-05-15
BR9800323B1 (en) 2011-04-19
CZ297419B6 (en) 2006-12-13
HU227154B1 (en) 2010-08-30
NZ329572A (en) 1999-05-28
DE69813322D1 (en) 2003-05-22
HU9800056D0 (en) 1998-03-02
HUP9800056A3 (en) 2001-01-29
PL324279A1 (en) 1998-07-20
JP4353549B2 (en) 2009-10-28
DE69813322T2 (en) 2004-02-19
NO2010013I1 (en) 2010-06-07
DK0853945T3 (en) 2003-08-04
EP0853945A1 (en) 1998-07-22
US5929028A (en) 1999-07-27
RU2203086C2 (en) 2003-04-27
MX9800438A (en) 1998-11-30
FR10C0024I1 (en) 2010-05-21
DE122010000011I1 (en) 2010-07-08
KR100498531B1 (en) 2005-09-30
NO2021001I1 (en) 2021-01-12
SA98181124B1 (en) 2006-07-10
KR19980070493A (en) 1998-10-26
NO2010013I2 (en) 2015-05-18
EP1285665A1 (en) 2003-02-26
PL190103B1 (en) 2005-10-31

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