FR09C0006I1 - - Google Patents

Info

Publication number
FR09C0006I1
FR09C0006I1 FR09C0006C FR09C0006I1 FR 09C0006 I1 FR09C0006 I1 FR 09C0006I1 FR 09C0006 C FR09C0006 C FR 09C0006C FR 09C0006 I1 FR09C0006 I1 FR 09C0006I1
Authority
FR
France
Prior art keywords
animal
unsubstituted
chem
administering
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21760388&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR09C0006(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of FR09C0006I1 publication Critical patent/FR09C0006I1/fr
Application granted granted Critical
Publication of FR09C0006I2 publication Critical patent/FR09C0006I2/fr
Active legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR09C0006C 1996-03-15 2009-02-26 Derives aminoacides enantiomeriques ayant un effet anti-convulsif Active FR09C0006I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1352296P 1996-03-15 1996-03-15
PCT/US1997/004579 WO1997033861A1 (en) 1996-03-15 1997-03-17 Anticonvulsant enantiomeric amino acid derivatives

Publications (2)

Publication Number Publication Date
FR09C0006I1 true FR09C0006I1 (ko) 2009-04-17
FR09C0006I2 FR09C0006I2 (fr) 2009-12-18

Family

ID=21760388

Family Applications (1)

Application Number Title Priority Date Filing Date
FR09C0006C Active FR09C0006I2 (fr) 1996-03-15 2009-02-26 Derives aminoacides enantiomeriques ayant un effet anti-convulsif

Country Status (12)

Country Link
EP (2) EP1038522B1 (ko)
JP (1) JP3145414B2 (ko)
AT (2) ATE268169T1 (ko)
AU (1) AU718577B2 (ko)
CA (1) CA2248317C (ko)
DE (3) DE69705210T2 (ko)
DK (2) DK0888289T3 (ko)
ES (2) ES2218024T3 (ko)
FR (1) FR09C0006I2 (ko)
NL (1) NL300376I1 (ko)
PT (2) PT1038522E (ko)
WO (1) WO1997033861A1 (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048899A (en) * 1997-03-17 2000-04-11 Research Corporation Tech., Inc. Anticonvulsant enantiomeric amino acid derivatives
EP1642889A1 (en) * 2004-10-02 2006-04-05 Schwarz Pharma Ag Improved synthesis scheme for lacosamide
EP1873527A1 (en) 2006-06-30 2008-01-02 Schwarz Pharma Ag Method for identifying CRMP modulators
US8093426B2 (en) 2007-12-04 2012-01-10 Ranbaxy Laboratories Limited Intermediate compounds and their use in preparation of lacosamide
DE102008059155A1 (de) 2008-11-27 2010-06-02 Ratiopharm Gmbh Trockenverarbeitung und neue Formen von Lacosamid
CN102596897A (zh) 2009-08-06 2012-07-18 麦迪凯姆股份公司 一种n-(苯基甲基)丙酰胺衍生物的多种固体形态及制备方法
JP5564570B2 (ja) * 2009-09-25 2014-07-30 カディラ・ヘルスケア・リミテッド ラコサミドおよびその中間体の調製方法
IT1398044B1 (it) * 2010-01-29 2013-02-07 Archimica Srl Processo per la preparazione della lacosamide
KR20120128667A (ko) 2010-02-08 2012-11-27 낫코 파마 리미티드 라코사미드의 제조방법
US8907132B2 (en) * 2010-02-09 2014-12-09 Msn Laboratories Private Limited Process for preparing (R)-2-acetamido-N-benzyl-3-methoxy-propionamide
EP2399901A1 (en) 2010-06-23 2011-12-28 Archimica GmbH Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide
EP2621893A1 (en) 2010-10-01 2013-08-07 UCB Pharma GmbH Process for the preparation of amino acid derivatives
US9226971B2 (en) 2010-10-15 2016-01-05 Nektar Therapeutics N-optionally substituted aryl-2-oligomer-3-alkoxypropionamides
EP2444390B1 (en) 2010-10-19 2017-02-01 Euticals GmbH Process for producing Lacosamide
NZ610701A (en) 2010-12-02 2015-06-26 Ucb Pharma Gmbh Once daily formulation of lacosamide
EP2468261A1 (en) 2010-12-02 2012-06-27 UCB Pharma GmbH Formulation of lacosamide
CN104771356A (zh) * 2014-01-09 2015-07-15 山东方明药业集团股份有限公司 一种拉科酰胺注射液及其制备方法
US11278634B1 (en) 2021-02-12 2022-03-22 Extrovis Ag Stable parenteral composition of lacosamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378729A (en) * 1985-02-15 1995-01-03 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
CA1340902C (en) * 1985-02-15 2000-02-22 Harold L. Kohn Amino acid derivative anticonvulsant

Also Published As

Publication number Publication date
DE69729392D1 (de) 2004-07-08
EP1038522A2 (en) 2000-09-27
CA2248317C (en) 2003-12-02
JP2000505476A (ja) 2000-05-09
ATE202079T1 (de) 2001-06-15
ES2218024T3 (es) 2004-11-16
AU718577B2 (en) 2000-04-13
EP1038522A3 (en) 2003-01-15
DE122009000010I2 (de) 2010-10-21
DE69705210D1 (de) 2001-07-19
EP0888289B1 (en) 2001-06-13
DE69729392T2 (de) 2005-06-02
PT888289E (pt) 2001-09-28
ATE268169T1 (de) 2004-06-15
FR09C0006I2 (fr) 2009-12-18
EP0888289A1 (en) 1999-01-07
JP3145414B2 (ja) 2001-03-12
AU2539497A (en) 1997-10-01
DK1038522T3 (da) 2004-10-11
EP1038522B1 (en) 2004-06-02
CA2248317A1 (en) 1997-09-18
DE69705210T2 (de) 2001-09-20
DE122009000010I1 (de) 2009-05-20
DK0888289T3 (da) 2001-09-03
PT1038522E (pt) 2004-10-29
ES2157567T3 (es) 2001-08-16
NL300376I1 (nl) 2009-05-06
WO1997033861A1 (en) 1997-09-18

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