FR07C0073I2 - PAPILLOMAVIRUS VACCINE - Google Patents

PAPILLOMAVIRUS VACCINE

Info

Publication number
FR07C0073I2
FR07C0073I2 FR07C0073C FR07C0073C FR07C0073I2 FR 07C0073 I2 FR07C0073 I2 FR 07C0073I2 FR 07C0073 C FR07C0073 C FR 07C0073C FR 07C0073 C FR07C0073 C FR 07C0073C FR 07C0073 I2 FR07C0073 I2 FR 07C0073I2
Authority
FR
France
Prior art keywords
antibodies
useful
papillomavirus vaccine
mimics
diagnosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR07C0073C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Georgetown University
Original Assignee
Georgetown University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25416951&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR07C0073(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Georgetown University filed Critical Georgetown University
Publication of FR07C0073I1 publication Critical patent/FR07C0073I1/fr
Application granted granted Critical
Publication of FR07C0073I2 publication Critical patent/FR07C0073I2/en
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A recombinantly produced L1 major capsid protein which mimics conformational neutralizing epitopes on human and animal papilloma virions is provided. The recombinant proteins are useful as vaccines protective against papillomavirus infection. Antibodies to the recombinant protein are also provided. Such antibodies are useful in the diagnosis and treatment of viral infection.
FR07C0073C 1992-06-25 2007-12-21 PAPILLOMAVIRUS VACCINE Active FR07C0073I2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90310992A 1992-06-25 1992-06-25
PCT/US1993/006109 WO1994000152A1 (en) 1992-06-25 1993-06-24 Papillomavirus vaccines

Publications (2)

Publication Number Publication Date
FR07C0073I1 FR07C0073I1 (en) 2008-01-02
FR07C0073I2 true FR07C0073I2 (en) 2012-08-03

Family

ID=25416951

Family Applications (1)

Application Number Title Priority Date Filing Date
FR07C0073C Active FR07C0073I2 (en) 1992-06-25 2007-12-21 PAPILLOMAVIRUS VACCINE

Country Status (12)

Country Link
US (2) US20020068326A1 (en)
EP (2) EP1835029A1 (en)
AT (1) ATE380871T1 (en)
AU (1) AU697743C (en)
DE (9) DE122007000097I1 (en)
DK (1) DK0647140T3 (en)
ES (1) ES2294778T3 (en)
FR (1) FR07C0073I2 (en)
LU (8) LU91395I2 (en)
NL (8) NL300316I1 (en)
PT (1) PT647140E (en)
WO (1) WO1994000152A1 (en)

Families Citing this family (57)

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DK0595935T3 (en) 1991-07-19 2003-07-21 Csl Ltd Papillomavirus Vaccine
US5437951A (en) 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
US6153201A (en) * 1993-03-09 2000-11-28 University Of Rochester Oral immunization with papillomavirus virus-like particles
US8062642B1 (en) 1993-03-09 2011-11-22 University Of Rochester Production of papillomavirus capsid protein and virus-like particles
DE4415743C2 (en) * 1994-05-04 1996-10-10 Deutsches Krebsforsch Papillomaviruses, means for their detection and for the therapy of diseases caused by them
HUT76354A (en) * 1994-05-16 1997-08-28 Merck & Co Inc Papillomavirus vaccines
US5888516A (en) * 1994-05-16 1999-03-30 Merck & Co. Inc. Recombinant papillomavirus vaccines
AU683564B2 (en) * 1994-05-17 1997-11-13 University Of Queensland, The Recombinant papilloma virus L1
AUPM566794A0 (en) * 1994-05-17 1994-06-09 University Of Queensland, The Process and product
WO1996009375A1 (en) * 1994-09-22 1996-03-28 Merck & Co., Inc. Dna encoding human papillomavirus type 6a
WO1996011272A2 (en) 1994-10-07 1996-04-18 Medigene Gesellschaft Für Molekularbiologische Diagnostik, Theraphie Und Technologie Mbh Papilloma virus-like particles, fusion proteins and process for producing the same
US5820870A (en) * 1995-03-22 1998-10-13 Merck & Co., Inc. Recombinant human papillomavirus type 18 vaccine
US5840306A (en) * 1995-03-22 1998-11-24 Merck & Co., Inc. DNA encoding human papillomavirus type 18
IL117459A (en) * 1995-03-22 2005-11-20 Merck & Co Inc Dna encoding human papillomavirus type 18
US6908615B1 (en) 1996-03-18 2005-06-21 Merck & Co., Inc. DNA encoding human papilloma virus type 18
GB9621091D0 (en) 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
EP1000157A1 (en) * 1997-07-03 2000-05-17 University Technology Corporation Homogeneous human papilloma virus capsomere containing compositions, methods for manufacture, and the use thereof as diagnostic, prophylactic or therapy
US6228368B1 (en) 1997-10-06 2001-05-08 Loyola University Of Chicago Papilloma virus capsomere formulations and method of use
US20020039584A1 (en) 1998-02-20 2002-04-04 Medigene Ag Papilloma virus capsomere vaccine formulations and methods of use
CA2229955C (en) 1998-02-20 2003-12-09 Medigene Gmbh Papilloma virus capsomere vaccine formulations and methods of use
US7494658B2 (en) 1998-02-20 2009-02-24 Medigene Ag Papilloma virus truncated L1 protein and fusion protein constructs
US7182947B2 (en) 1998-02-20 2007-02-27 Medigene Ag Papillomavirus truncated L1 protein and fusion protein constructs
US6926897B1 (en) 1998-03-24 2005-08-09 Medigene Aktiengesellschaft Medicament for the avoidance or treatment of papillomavirus-specific tumour
US6242176B1 (en) 1998-07-13 2001-06-05 Loyola University Of Chicago Papillomavirus cellular receptor
US6692752B1 (en) 1999-09-08 2004-02-17 Smithkline Beecham Biologicals S.A. Methods of treating human females susceptible to HSV infection
DE69935606T9 (en) * 1998-10-16 2021-03-11 Glaxosmithkline Biologicals S.A. ADJUVANCE SYSTEMS AND VACCINE
GB0109297D0 (en) 2001-04-12 2001-05-30 Glaxosmithkline Biolog Sa Vaccine
ATE471990T1 (en) 2001-08-13 2010-07-15 Univ Rochester TRANSCUTANE IMMUNIZATION AGAINST PAPILLOMAVIRUS WITH VIRUS-LIKE PAPILLOMAVIRUS PARTICLES
GB0206360D0 (en) * 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
CA2531773A1 (en) 2003-07-21 2005-02-17 Transgene S.A. Novel multifunctional cytokines
TWI457133B (en) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa Novel composition
US20090181078A1 (en) 2006-09-26 2009-07-16 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
CN101516396B (en) 2006-09-26 2013-10-09 传染性疾病研究院 Vaccine composition containing synthetic adjuvant
CL2008000611A1 (en) 2007-03-02 2008-09-05 Glaxosmithkline Biolog Sa PROCEDURE TO PROMOTE IMMUNE RESPONSE AGAINST A PATHOGEN UNDERSTANDING I) ONE OR MORE IMMUNOGENIC POLYPEPTIDES DERIVED FROM THE PATHOGEN, II) ONE OR MORE ADENOVIRICAL VECTORS UNDERSTANDING ONE OR MORE POLINUCLEODICS
US9623098B2 (en) 2008-05-26 2017-04-18 Cadila Healthcare Limited Combined measles-human papilloma vaccine
GB0815872D0 (en) 2008-09-01 2008-10-08 Pasteur Institut Novel method and compositions
GB0820822D0 (en) 2008-11-13 2008-12-24 Inst Catala D Oncologia Novel product and processes
EP2414512A1 (en) * 2009-04-03 2012-02-08 Deutsches Krebsforschungszentrum Enhanced production of papillomavirus-like particles with a modified baculovirus expression system
US8722064B2 (en) 2009-06-05 2014-05-13 Infectious Disease Research Institute Synthetic glucopyranosyl lipid adjuvants
WO2011026111A1 (en) 2009-08-31 2011-03-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Oral delivery of a vaccine to the large intestine to induce mucosal immunity
EP2556377B1 (en) 2010-04-08 2017-07-12 University of Pittsburgh - Of the Commonwealth System of Higher Education B-cell antigen presenting cell assay
EP3632463A1 (en) 2011-04-08 2020-04-08 Immune Design Corp. Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses
PL2811981T3 (en) 2012-02-07 2019-09-30 Infectious Disease Research Institute Improved adjuvant formulations comprising tlr4 agonists and methods of using the same
NZ701881A (en) 2012-05-16 2016-10-28 Immune Design Corp Vaccines for hsv-2
CN104870477B (en) 2012-10-23 2018-10-09 爱默蕾大学 GM-CSF and IL-4 conjugates, composition and relative method
EP3711768A1 (en) 2013-04-18 2020-09-23 Immune Design Corp. Gla monotherapy for use in cancer treatment
US9463198B2 (en) 2013-06-04 2016-10-11 Infectious Disease Research Institute Compositions and methods for reducing or preventing metastasis
EP3915579A1 (en) 2013-12-31 2021-12-01 Infectious Disease Research Institute Single vial vaccine formulations
JP7005504B2 (en) 2016-02-22 2022-01-21 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー Biomolecule immobilization method
EP3458475B1 (en) 2016-05-16 2022-07-27 Access to Advanced Health Institute Formulation containing tlr agonist and methods of use
MX2018013640A (en) 2016-05-16 2019-08-01 Infectious Disease Res Inst Pegylated liposomes and methods of use.
IL298227B1 (en) 2016-06-01 2024-05-01 Access To Advanced Health Inst Nanoalum particles containing a sizing agent
US11141377B2 (en) 2017-06-15 2021-10-12 Infectious Disease Research Institute Nanostructured lipid carriers and stable emulsions and uses thereof
US20200276299A1 (en) 2017-09-08 2020-09-03 Infectious Disease Research Institute Liposomal formulations comprising saponin and methods of use
MX2021014363A (en) 2019-05-25 2022-02-21 Infectious Disease Res Inst Composition and method for spray drying an adjuvant vaccine emulsion.
AU2021337493A1 (en) 2020-09-04 2023-05-18 Access To Advanced Health Institute Co-lyophilized rna and nanostructured lipid carrier
WO2024052882A1 (en) 2022-09-09 2024-03-14 Access To Advanced Health Institute Immunogenic vaccine composition incorporating a saponin

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JPS57106626A (en) * 1980-12-22 1982-07-02 Teijin Ltd Cytotoxic protein complex and its preparation
US4455296A (en) * 1982-02-02 1984-06-19 Board Of Regents, The University Of Texas System Hybrid cell lines producing monoclonal antibodies directed against Haemophilus influenzae
US4671958A (en) * 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
FR2524487B1 (en) * 1982-04-05 1985-11-22 Pasteur Institut DNA FRAGMENTS ENCODING POLYPEPTIDES CONTAINING AT LEAST ONE ANTIGENIC DETERMINANT OF PAPILLOMAVIRUS, IN PARTICULAR OF THE HPV 1A TYPE AND CORRESPONDING POLYPEPTIDES
US4596674A (en) * 1984-09-11 1986-06-24 Merck & Co., Inc. Immunogenic HAV peptides
DE3625257A1 (en) * 1986-07-23 1988-02-04 Behringwerke Ag EXPRESSION PRODUCTS OF THE HUMAN PAPILLOMVIRUS TYPE 16 AND 18, FOR THESE PROTEINS, SPECIFIC ANTIBODIES AND THESE ANTIBODIES OR. CORRESPONDING DNA-CONTAINING DIAGNOSTICS
NZ223009A (en) * 1986-12-31 1990-06-26 Nl Rivm Of Thoven Oligosaccharides containing d-ribose d-ribitol and phosphate units mimicing haemophilus influenzae type b antigens
EP0320942A3 (en) * 1987-12-18 1989-10-04 American Cyanamid Company Novel polysaccharides novel macromolecular conjugates of the polysaccharides
PT97073A (en) * 1990-03-20 1991-10-31 Behringwerke Ag PROCESS FOR THE PREPARATION OF HUMAN PAPILLOMAVIRUS 16 PROTEIN SORO-REACTIVE EPITHOPES (HPV)
DK0595935T3 (en) 1991-07-19 2003-07-21 Csl Ltd Papillomavirus Vaccine

Also Published As

Publication number Publication date
LU91397I2 (en) 2008-02-14
DE122007000098I1 (en) 2008-03-27
NL300320I1 (en) 2008-03-03
LU91398I2 (en) 2008-02-14
LU91394I2 (en) 2008-02-14
DE122007000101I1 (en) 2008-03-27
ATE380871T1 (en) 2007-12-15
AU1135295A (en) 1996-02-08
NL300318I2 (en) 2008-03-03
EP0647140A4 (en) 1997-03-19
NL300315I2 (en) 2008-03-03
NL300315I1 (en) 2008-02-01
NL300319I1 (en) 2008-03-03
LU91400I2 (en) 2008-02-14
NL300321I1 (en) 2008-03-03
DE122007000100I1 (en) 2008-03-27
US20020068326A1 (en) 2002-06-06
EP1835029A1 (en) 2007-09-19
PT647140E (en) 2007-12-27
DE122007000096I1 (en) 2008-03-27
ES2294778T3 (en) 2008-04-01
NL300317I1 (en) 2008-02-01
WO1994000152A1 (en) 1994-01-06
DE122007000094I1 (en) 2008-03-27
DE69334192T2 (en) 2008-12-04
DE122007000097I1 (en) 2008-03-27
US8012679B1 (en) 2011-09-06
NL300316I1 (en) 2008-02-01
NL300322I1 (en) 2008-03-03
LU91399I2 (en) 2008-02-14
LU91393I2 (en) 2008-02-14
DE69334192D1 (en) 2008-01-24
DE122007000095I1 (en) 2008-03-27
EP0647140B1 (en) 2007-12-12
AU697743C (en) 2007-06-14
LU91396I2 (en) 2008-02-14
NL300318I1 (en) 2008-02-01
EP0647140A1 (en) 1995-04-12
LU91395I2 (en) 2008-02-14
FR07C0073I1 (en) 2008-01-02
AU697743B2 (en) 1998-10-15
DE122007000099I1 (en) 2008-03-27
DK0647140T3 (en) 2008-02-04

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