FR05C0045I2 - - Google Patents
Info
- Publication number
- FR05C0045I2 FR05C0045I2 FR05C0045C FR05C0045C FR05C0045I2 FR 05C0045 I2 FR05C0045 I2 FR 05C0045I2 FR 05C0045 C FR05C0045 C FR 05C0045C FR 05C0045 C FR05C0045 C FR 05C0045C FR 05C0045 I2 FR05C0045 I2 FR 05C0045I2
- Authority
- FR
- France
- Prior art keywords
- pct
- date sep
- sec
- pub
- antiobiotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
PCT No. PCT/US94/01862 Sec. 371 Date Sep. 11, 1995 Sec. 102(e) Date Sep. 11, 1995 PCT Filed Mar. 7, 1994 PCT Pub. No. WO94/20505 PCT Pub. Date Sep. 15, 1994Anhydrous and crystalline free acid form of the cephalosporin antiobiotic ceftiofur, processes for its manufacture, and pharmaceutical composition containing it are provided.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3329193A | 1993-03-12 | 1993-03-12 | |
PCT/US1994/001862 WO1994020505A1 (en) | 1993-03-12 | 1994-03-07 | Crystalline ceftiofur free acid |
Publications (2)
Publication Number | Publication Date |
---|---|
FR05C0045I1 FR05C0045I1 (en) | 2006-01-06 |
FR05C0045I2 true FR05C0045I2 (en) | 2007-08-03 |
Family
ID=21869579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR05C0045C Active FR05C0045I2 (en) | 1993-03-12 | 2005-11-17 |
Country Status (31)
Country | Link |
---|---|
US (1) | US5721359A (en) |
EP (1) | EP0690864B1 (en) |
JP (1) | JP3852946B2 (en) |
KR (1) | KR100296810B1 (en) |
CN (1) | CN1055090C (en) |
AT (1) | ATE202109T1 (en) |
AU (1) | AU694419B2 (en) |
BR (1) | BR1101034A (en) |
CA (1) | CA2155322C (en) |
CZ (1) | CZ289332B6 (en) |
DE (2) | DE69427469T2 (en) |
DK (1) | DK0690864T3 (en) |
ES (1) | ES2157254T3 (en) |
FI (1) | FI120307B (en) |
FR (1) | FR05C0045I2 (en) |
GR (1) | GR3036514T3 (en) |
HU (1) | HU222244B1 (en) |
IL (1) | IL108910A (en) |
LU (1) | LU91206I2 (en) |
LV (1) | LV12889B (en) |
NL (1) | NL300208I2 (en) |
NO (2) | NO313199B1 (en) |
NZ (1) | NZ263002A (en) |
PL (1) | PL184611B1 (en) |
PT (1) | PT690864E (en) |
RU (1) | RU2136685C1 (en) |
SI (1) | SI0690864T1 (en) |
SK (1) | SK283674B6 (en) |
TW (1) | TW267170B (en) |
WO (1) | WO1994020505A1 (en) |
ZA (1) | ZA941586B (en) |
Families Citing this family (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5736151A (en) * | 1996-12-09 | 1998-04-07 | Pharmacia & Upjohn Company | Antibiotic oil suspensions |
US6074657A (en) * | 1997-03-20 | 2000-06-13 | Pharmacia & Upjohn Company | Administration of an injectable antibiotic in the ear of an animal |
EP1317256B1 (en) * | 2000-09-12 | 2008-10-29 | Pharmacia & Upjohn Company LLC | Pharmaceutical composition having modified carrier |
US7829100B2 (en) * | 2000-09-12 | 2010-11-09 | Teagarden Dirk L | Pharmaceutical composition having modified carrier |
KR100423895B1 (en) * | 2001-02-19 | 2004-03-24 | 주식회사 엘지생명과학 | Compositions of suspensions of ceftiofur hydrochloride |
CA2453182A1 (en) * | 2001-07-10 | 2003-01-23 | Meredith L. Greene | Crystalline thiazine oxazolidinones |
EP3168218B1 (en) | 2001-08-15 | 2018-11-14 | Pharmacia & Upjohn Company LLC | A crystal comprising an l-malic acid salt of n-[2-(diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide for use as a medicament |
KR20040097187A (en) † | 2002-03-21 | 2004-11-17 | 파마시아 앤드 업존 캄파니 | Method of administering an injectable antibiotic to the ear of an animal |
US20040022815A1 (en) * | 2002-08-05 | 2004-02-05 | Orchid Health Care | Novel pharmaceutical composition of ceftiofur |
KR20040015622A (en) * | 2002-08-13 | 2004-02-19 | 대한뉴팜(주) | Injectable Composition Comprising Ceftiofur Sodium as Active Ingredient |
US20040115822A1 (en) * | 2002-09-12 | 2004-06-17 | Schapaugh Randal Lee | Methods of measuring the dissolution rate of an analyte in a non-aqueous liquid composition |
US7659061B2 (en) * | 2002-11-19 | 2010-02-09 | Pharmacia & Upjohn Company | Pharmaceutical compositions having a modified vehicle |
US20040115837A1 (en) * | 2002-11-27 | 2004-06-17 | Schapaugh Randal Lee | Methods of measuring the dissolution rate of an analyte in a non-aqueous liquid composition |
US7842791B2 (en) * | 2002-12-19 | 2010-11-30 | Nancy Jean Britten | Dispersible pharmaceutical compositions |
JP5230934B2 (en) * | 2003-03-27 | 2013-07-10 | バジリア ファルマスーチカ アーゲー | Crystalline cephalosporin |
WO2005092889A1 (en) | 2004-03-25 | 2005-10-06 | Astellas Pharma Inc. | Composition for solid pharmaceutical preparation of solifenacin or salt thereof |
US7815939B2 (en) | 2005-07-20 | 2010-10-19 | Astellas Pharma Inc. | Coated fine particles containing drug for intrabuccally fast disintegrating dosage forms |
BRPI0617561A2 (en) * | 2005-10-12 | 2011-08-23 | Orchid Chemicals & Pharm Ltd | cephalosporin antibiotic crystalline sodium salt |
US8470809B2 (en) * | 2005-10-12 | 2013-06-25 | Orchid Chemicals & Pharmaceuticals Limited | Crystalline sodium salt of cephalosporin antibiotic |
TW201446748A (en) | 2007-08-22 | 2014-12-16 | Astrazeneca Ab | Cyclopropyl amide derivatives |
EP2303026B1 (en) | 2008-06-17 | 2020-09-09 | Brigham Young University | Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods |
US8431562B2 (en) * | 2008-08-22 | 2013-04-30 | Orchid Chemicals & Pharmaceuticals Limited | Crystalline sodium salt of cephalosporin antibiotic |
WO2010059717A2 (en) * | 2008-11-19 | 2010-05-27 | Merial Limited | Formulations comprising ceftiofur and ketoprofen or ceftiofur and benzyl alcohol |
PE20120003A1 (en) * | 2009-01-30 | 2012-02-12 | Glaxosmithkline Llc | N - {(1S) -2-AMINO-1 - [(3-FLUOROPHENYL) METHYL) ETHYL HYDROCHLORIDE} -5-CHLORO-4- (4-CHLORO-1-METHYL-1H-PIRAZOL-5-IL) - CRYSTALLINE 2-THIOPHENOCARBOXAMIDE |
TW201039825A (en) | 2009-02-20 | 2010-11-16 | Astrazeneca Ab | Cyclopropyl amide derivatives 983 |
BR112012020629A2 (en) | 2010-02-18 | 2018-06-19 | Astrazeneca Ab | crystalline form and method for the therapy of a disorder |
CA2789884A1 (en) * | 2010-02-18 | 2011-08-25 | Astrazeneca Ab | Solid forms comprising a cyclopropyl amide derivative |
EP2705044A1 (en) | 2011-05-02 | 2014-03-12 | Zoetis Llc | Novel cephalosporins useful as antibacterial agents |
US8975310B2 (en) | 2011-07-20 | 2015-03-10 | Brigham Young University | Hydrophobic ceragenin compounds and devices incorporating same |
US9694019B2 (en) | 2011-09-13 | 2017-07-04 | Brigham Young University | Compositions and methods for treating bone diseases and broken bones |
MX369385B (en) | 2011-09-13 | 2019-11-07 | Univ Brigham Young | Products for healing of tissue wounds. |
CA2852989C (en) | 2011-09-13 | 2021-06-29 | Brigham Young University | Compositions for treating bone diseases and broken bones |
US9603859B2 (en) | 2011-09-13 | 2017-03-28 | Brigham Young University | Methods and products for increasing the rate of healing of tissue wounds |
JP6051230B2 (en) | 2011-12-21 | 2016-12-27 | ブリガム ヤング ユニバーシティ | Oral care composition |
CN102584855B (en) * | 2012-02-16 | 2014-06-25 | 青岛科技大学 | Improved method for preparing ceftiofur |
US9533063B1 (en) | 2012-03-01 | 2017-01-03 | Brigham Young University | Aerosols incorporating ceragenin compounds and methods of use thereof |
EP3225113B1 (en) | 2012-05-02 | 2020-09-02 | Brigham Young University | Methods for making ceragenin particulate materials |
WO2014062960A1 (en) | 2012-10-17 | 2014-04-24 | Brigham Young University | Treatment and prevention of mastitis |
WO2014087972A1 (en) * | 2012-12-03 | 2014-06-12 | 株式会社カネカ | Reduced coenzyme q10 derivative and method for producing same |
CA2897150C (en) | 2013-01-07 | 2021-07-13 | Brigham Young University | Methods for reducing cellular proliferation and treating certain diseases |
RU2669800C2 (en) | 2013-03-15 | 2018-10-16 | Брихэм Янг Юниверсити | Methods for treating inflammation, autoimmune disorders and pain |
US10568893B2 (en) | 2013-03-15 | 2020-02-25 | Brigham Young University | Methods for treating inflammation, autoimmune disorders and pain |
US11524015B2 (en) | 2013-03-15 | 2022-12-13 | Brigham Young University | Methods for treating inflammation, autoimmune disorders and pain |
RU2546675C2 (en) * | 2013-04-11 | 2015-04-10 | Федеральное казённое предприятие "Государственный научно-исследовательский институт химических продуктов" (ФКП "ГосНИИХП") | Method of determining crystallinity of diphenylamine-based compositions |
US9387215B2 (en) | 2013-04-22 | 2016-07-12 | Brigham Young University | Animal feed including cationic cholesterol additive and related methods |
KR20230159631A (en) * | 2013-09-05 | 2023-11-21 | 미쓰비시 타나베 파마 코퍼레이션 | Novel crystalline arylalkylamine compound and method for producing same |
US11690855B2 (en) | 2013-10-17 | 2023-07-04 | Brigham Young University | Methods for treating lung infections and inflammation |
US20150203527A1 (en) | 2014-01-23 | 2015-07-23 | Brigham Young University | Cationic steroidal antimicrobials |
CA2844321C (en) | 2014-02-27 | 2021-03-16 | Brigham Young University | Cationic steroidal antimicrobial compounds |
US10220045B2 (en) | 2014-03-13 | 2019-03-05 | Brigham Young University | Compositions and methods for forming stabilized compositions with reduced CSA agglomeration |
US9867836B2 (en) | 2014-03-13 | 2018-01-16 | Brigham Young University | Lavage and/or infusion using CSA compounds for increasing fertility in a mammal |
US9931350B2 (en) | 2014-03-14 | 2018-04-03 | Brigham Young University | Anti-infective and osteogenic compositions and methods of use |
US9686966B2 (en) | 2014-04-30 | 2017-06-27 | Brigham Young University | Methods and apparatus for cleaning or disinfecting a water delivery system |
US10441595B2 (en) | 2014-06-26 | 2019-10-15 | Brigham Young University | Methods for treating fungal infections |
US10238665B2 (en) | 2014-06-26 | 2019-03-26 | Brigham Young University | Methods for treating fungal infections |
US10227376B2 (en) | 2014-08-22 | 2019-03-12 | Brigham Young University | Radiolabeled cationic steroid antimicrobials and diagnostic methods |
US10155788B2 (en) | 2014-10-07 | 2018-12-18 | Brigham Young University | Cationic steroidal antimicrobial prodrug compositions and uses thereof |
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WO2016172543A1 (en) | 2015-04-22 | 2016-10-27 | Savage Paul B | Methods for the synthesis of ceragenins |
US9527883B2 (en) | 2015-04-22 | 2016-12-27 | Brigham Young University | Methods for the synthesis of ceragenins |
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MA45588A (en) | 2016-07-07 | 2019-05-15 | Ironwood Pharmaceuticals Inc | SOLID FORMS OF A GCS STIMULATOR |
US10959433B2 (en) | 2017-03-21 | 2021-03-30 | Brigham Young University | Use of cationic steroidal antimicrobials for sporicidal activity |
US11186556B1 (en) * | 2018-10-16 | 2021-11-30 | Celgene Corporation | Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof |
TW202233625A (en) * | 2020-11-18 | 2022-09-01 | 美商傳達治療有限公司 | Fgfr inhibitors and methods of making and using the same |
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DE1207933B (en) * | 1962-12-26 | 1965-12-30 | American Home Prod | Process for the preparation of D-alpha-aminobenzylpenicillin free of water of crystallization |
CY773A (en) * | 1967-09-05 | 1975-03-01 | Bristol Myers Co | Antibacterial agents and a process for the preparation thereof |
DK154939C (en) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | METHOD OF ANALOGUE FOR THE PREPARATION OF THIAZOLYLACETAMIDO-CEPHEM COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE SALTS OR ESTERS THEREOF |
DE2760123C2 (en) * | 1976-01-23 | 1986-04-30 | Roussel-Uclaf, Paris | 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporanic acids, their preparation and pharmaceutical compositions containing them |
GB1532682A (en) * | 1976-04-27 | 1978-11-22 | Bristol Myers Co | Process for the preparation of cephadroxil |
FR2479229B1 (en) * | 1980-03-26 | 1986-01-17 | Clin Midy | NOVEL CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS FOR USE AS ANTIBIOTICS CONTAINING SAID DERIVATIVES |
IL63968A (en) * | 1980-10-01 | 1985-10-31 | Glaxo Group Ltd | Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it |
US4400503A (en) * | 1981-10-30 | 1983-08-23 | Eli Lilly And Company | Purification of syn-7-[[(2-amino-4-thiazolyl)(methoxyimino) acetyl]amino]-3-methyl-3-cephem-4-carboxylic acid |
DE3313818A1 (en) * | 1983-04-16 | 1984-10-18 | Hoechst Ag, 6230 Frankfurt | NEW CEFTAZIDIM CRYSTAL MODIFICATION |
HU196714B (en) * | 1984-10-04 | 1989-01-30 | Monsanto Co | Process for producing non-aqueous composition comprising somatotropin |
IT1181672B (en) * | 1984-10-25 | 1987-09-30 | Upjohn Co | CRYSTALLINE HALOGENHYDRATE CEPHALOSPORINE |
US4902683A (en) * | 1984-10-25 | 1990-02-20 | The Upjohn Company | Crystalline cephalosporin hydrohalide salts |
JPH0749432B2 (en) * | 1985-08-12 | 1995-05-31 | ジ・アップジョン・カンパニ− | Conversion of cephalosporin hydrohalides to alkali metal salts |
GB8608962D0 (en) * | 1986-04-12 | 1986-05-14 | Beecham Group Plc | Beta-lactam antibiotics |
IT1214587B (en) * | 1986-12-23 | 1990-01-18 | Giovanni Bonfanti | METHOD FOR THE PRODUCTION OF PURE CRYSTALLINE PRODUCTS. |
ES2032543T3 (en) * | 1987-02-02 | 1993-02-16 | Eli Lilly And Company | IMPROVED PROCEDURE FOR PREPARING AN ANTIBIOTIC. |
DE3869135D1 (en) * | 1987-07-29 | 1992-04-16 | Upjohn Co | CONTROLLED RELEASE OF ANTIBIOTIC SALT FROM AN IMPLANT. |
JP2703964B2 (en) * | 1987-11-10 | 1998-01-26 | ジ・アップジョン・カンパニー | Cephalosporin antibiotics |
US4877782A (en) * | 1988-02-16 | 1989-10-31 | The Upjohn Company | Zinc ceftiofur complexes |
-
1994
- 1994-03-07 SK SK1114-95A patent/SK283674B6/en not_active IP Right Cessation
- 1994-03-07 DK DK94910721T patent/DK0690864T3/en active
- 1994-03-07 ES ES94910721T patent/ES2157254T3/en not_active Expired - Lifetime
- 1994-03-07 RU RU95121942A patent/RU2136685C1/en active
- 1994-03-07 CN CN94191448A patent/CN1055090C/en not_active Expired - Lifetime
- 1994-03-07 DE DE69427469T patent/DE69427469T2/en not_active Expired - Lifetime
- 1994-03-07 KR KR1019950703858A patent/KR100296810B1/en not_active IP Right Cessation
- 1994-03-07 AT AT94910721T patent/ATE202109T1/en active
- 1994-03-07 ZA ZA941586A patent/ZA941586B/en unknown
- 1994-03-07 CA CA002155322A patent/CA2155322C/en not_active Expired - Lifetime
- 1994-03-07 SI SI9430374T patent/SI0690864T1/en unknown
- 1994-03-07 AU AU63510/94A patent/AU694419B2/en not_active Expired
- 1994-03-07 PT PT94910721T patent/PT690864E/en unknown
- 1994-03-07 US US08/549,821 patent/US5721359A/en not_active Expired - Lifetime
- 1994-03-07 NZ NZ263002A patent/NZ263002A/en not_active IP Right Cessation
- 1994-03-07 WO PCT/US1994/001862 patent/WO1994020505A1/en active IP Right Grant
- 1994-03-07 HU HU9501960A patent/HU222244B1/en active Protection Beyond IP Right Term
- 1994-03-07 PL PL94310556A patent/PL184611B1/en unknown
- 1994-03-07 JP JP52002594A patent/JP3852946B2/en not_active Expired - Lifetime
- 1994-03-07 DE DE122005000055C patent/DE122005000055I2/en active Active
- 1994-03-07 EP EP94910721A patent/EP0690864B1/en not_active Expired - Lifetime
- 1994-03-07 CZ CZ19952290A patent/CZ289332B6/en unknown
- 1994-03-09 IL IL10891094A patent/IL108910A/en not_active IP Right Cessation
- 1994-03-12 TW TW083102155A patent/TW267170B/zh not_active IP Right Cessation
-
1995
- 1995-09-11 NO NO19953564A patent/NO313199B1/en not_active IP Right Cessation
- 1995-09-11 FI FI954250A patent/FI120307B/en not_active IP Right Cessation
-
1997
- 1997-05-14 BR BR1101034-7A patent/BR1101034A/en active IP Right Grant
-
2001
- 2001-09-04 GR GR20010401374T patent/GR3036514T3/en unknown
-
2002
- 2002-06-13 LV LVP-02-107A patent/LV12889B/en unknown
-
2005
- 2005-11-16 LU LU91206C patent/LU91206I2/en unknown
- 2005-11-17 FR FR05C0045C patent/FR05C0045I2/fr active Active
- 2005-11-18 NO NO2005025C patent/NO2005025I2/en unknown
- 2005-11-21 NL NL300208C patent/NL300208I2/en unknown
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