FI972660A0 - Piperazine-2,5-dione derivatives as multidrug resistance modulators - Google Patents
Piperazine-2,5-dione derivatives as multidrug resistance modulatorsInfo
- Publication number
- FI972660A0 FI972660A0 FI972660A FI972660A FI972660A0 FI 972660 A0 FI972660 A0 FI 972660A0 FI 972660 A FI972660 A FI 972660A FI 972660 A FI972660 A FI 972660A FI 972660 A0 FI972660 A0 FI 972660A0
- Authority
- FI
- Finland
- Prior art keywords
- piperazine
- multidrug resistance
- dione derivatives
- resistance modulators
- modulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9426224.3A GB9426224D0 (en) | 1994-12-23 | 1994-12-23 | Pharmaceutical compounds |
| PCT/GB1995/003027 WO1996020190A1 (en) | 1994-12-23 | 1995-12-22 | Piperazine 2,5 dione derivatives as modulators of multi-drug resistance |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI972660A0 true FI972660A0 (en) | 1997-06-19 |
| FI972660A FI972660A (en) | 1997-08-22 |
Family
ID=10766589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI972660A FI972660A (en) | 1994-12-23 | 1997-06-19 | Piperazine-2,5-dione derivatives as multidrug resistance modulators |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0799222A1 (en) |
| JP (1) | JPH10511384A (en) |
| CN (1) | CN1175253A (en) |
| AU (1) | AU698828B2 (en) |
| BG (1) | BG101602A (en) |
| BR (1) | BR9510410A (en) |
| CA (1) | CA2207500A1 (en) |
| CZ (1) | CZ190097A3 (en) |
| FI (1) | FI972660A (en) |
| GB (1) | GB9426224D0 (en) |
| HU (1) | HUT77943A (en) |
| IL (1) | IL116525A0 (en) |
| NO (1) | NO972937D0 (en) |
| NZ (1) | NZ297847A (en) |
| PL (1) | PL320916A1 (en) |
| SK (1) | SK83697A3 (en) |
| TW (1) | TW358094B (en) |
| WO (1) | WO1996020190A1 (en) |
| ZA (1) | ZA9510909B (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100354265C (en) * | 1996-10-18 | 2007-12-12 | 埃克森诺瓦有限公司 | Pharmaceutical compounds |
| GB9717576D0 (en) * | 1997-08-19 | 1997-10-22 | Xenova Ltd | Pharmaceutical compounds |
| GB9708805D0 (en) | 1997-05-01 | 1997-06-25 | Smithkline Beecham Plc | Compounds |
| GB9810876D0 (en) | 1998-05-20 | 1998-07-22 | Smithkline Beecham Plc | Compounds |
| AR023681A1 (en) | 1998-10-08 | 2002-09-04 | Smithkline Beecham Plc | DERIVATIVES OF TETRAHYDROBENZAZEPINAS, PHARMACEUTICAL COMPOSITIONS AND THE USE OF THE SAME FOR THE MANUFACTURE OF A MEDICINAL PRODUCT. |
| WO2001053290A1 (en) * | 2000-01-18 | 2001-07-26 | Nippon Steel Corporation | Cell division inhibitors and process for producing the same |
| US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
| US7935704B2 (en) | 2003-08-01 | 2011-05-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
| DE60316688T2 (en) | 2002-08-02 | 2008-07-17 | Nereus Pharmaceuticals, Inc., San Diego | DEHYDROPHENYLAHISTINES AND ANALOGS THEREOF AND A PROCESS FOR THE PRODUCTION OF DEHYDROPHENYLAHISTINES AND ANALOGUE THEREOF |
| US7919497B2 (en) | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| US8129527B2 (en) | 2006-11-03 | 2012-03-06 | Nereus Pharmacuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| CN103396372B (en) * | 2013-08-09 | 2015-05-20 | 中国科学院南海海洋研究所 | 2,5-diketopiperazine derivative, as well as preparation method and application thereof in preparing control agent for resisting marine fouling organisms |
| MY190034A (en) | 2015-03-06 | 2022-03-22 | Beyondspring Pharmaceuticals Inc | Method of treating cancer associated with a ras mutation |
| EP3265091A4 (en) | 2015-03-06 | 2018-08-01 | Beyondspring Pharmaceuticals Inc. | Method of treating a brain tumor |
| JP6969848B2 (en) | 2015-07-13 | 2021-11-24 | ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド | Prinabrin composition |
| MY192703A (en) | 2016-02-08 | 2022-09-02 | Beyondspring Pharmaceuticals Inc | Compositions containing tucaresol or its analogs |
| SG11201810872UA (en) | 2016-06-06 | 2019-01-30 | Beyondspring Pharmaceuticals Inc | Composition and method for reducing neutropenia |
| EP3565812B1 (en) | 2017-01-06 | 2023-12-27 | Beyondspring Pharmaceuticals, Inc. | Tubulin binding compounds and therapeutic use thereof |
| EP3576733A4 (en) | 2017-02-01 | 2020-11-25 | Beyondspring Pharmaceuticals, Inc. | Method of reducing neutropenia |
| KR20200112881A (en) | 2018-01-24 | 2020-10-05 | 비욘드스프링 파마수티컬스, 인코포레이티드. | Composition and method for reducing thrombocytopenia through administration of plinabulin |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2103479T3 (en) * | 1992-07-10 | 1997-09-16 | Glaxo Lab Sa | ANILIDA DERIVATIVES. |
| GB9217331D0 (en) * | 1992-08-14 | 1992-09-30 | Xenova Ltd | Pharmaceutical compounds |
-
1994
- 1994-12-23 GB GBGB9426224.3A patent/GB9426224D0/en active Pending
-
1995
- 1995-12-21 ZA ZA9510909A patent/ZA9510909B/en unknown
- 1995-12-22 AU AU43100/96A patent/AU698828B2/en not_active Ceased
- 1995-12-22 CZ CZ971900A patent/CZ190097A3/en unknown
- 1995-12-22 SK SK836-97A patent/SK83697A3/en unknown
- 1995-12-22 BR BR9510410-0A patent/BR9510410A/en not_active Application Discontinuation
- 1995-12-22 PL PL95320916A patent/PL320916A1/en unknown
- 1995-12-22 IL IL11652595A patent/IL116525A0/en unknown
- 1995-12-22 JP JP8520301A patent/JPH10511384A/en active Pending
- 1995-12-22 WO PCT/GB1995/003027 patent/WO1996020190A1/en not_active Application Discontinuation
- 1995-12-22 EP EP95941797A patent/EP0799222A1/en not_active Withdrawn
- 1995-12-22 CA CA002207500A patent/CA2207500A1/en not_active Abandoned
- 1995-12-22 CN CN95197672A patent/CN1175253A/en active Pending
- 1995-12-22 HU HU9800398A patent/HUT77943A/en unknown
- 1995-12-22 NZ NZ297847A patent/NZ297847A/en unknown
- 1995-12-23 TW TW084113836A patent/TW358094B/en active
-
1997
- 1997-06-11 BG BG101602A patent/BG101602A/en unknown
- 1997-06-19 FI FI972660A patent/FI972660A/en unknown
- 1997-06-23 NO NO972937A patent/NO972937D0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2207500A1 (en) | 1996-07-04 |
| SK83697A3 (en) | 1998-05-06 |
| BG101602A (en) | 1998-02-27 |
| IL116525A0 (en) | 1996-03-31 |
| EP0799222A1 (en) | 1997-10-08 |
| AU698828B2 (en) | 1998-11-05 |
| FI972660A (en) | 1997-08-22 |
| PL320916A1 (en) | 1997-11-10 |
| CN1175253A (en) | 1998-03-04 |
| NO972937L (en) | 1997-06-23 |
| AU4310096A (en) | 1996-07-19 |
| HUT77943A (en) | 1998-12-28 |
| CZ190097A3 (en) | 1998-01-14 |
| NO972937D0 (en) | 1997-06-23 |
| NZ297847A (en) | 1999-04-29 |
| WO1996020190A1 (en) | 1996-07-04 |
| TW358094B (en) | 1999-05-11 |
| GB9426224D0 (en) | 1995-02-22 |
| JPH10511384A (en) | 1998-11-04 |
| ZA9510909B (en) | 1996-08-30 |
| BR9510410A (en) | 1999-09-08 |
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