FI953371A - Improved vaccines for immunization against TBE virus infection and method for their preparation - Google Patents

Improved vaccines for immunization against TBE virus infection and method for their preparation Download PDF

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Publication number
FI953371A
FI953371A FI953371A FI953371A FI953371A FI 953371 A FI953371 A FI 953371A FI 953371 A FI953371 A FI 953371A FI 953371 A FI953371 A FI 953371A FI 953371 A FI953371 A FI 953371A
Authority
FI
Finland
Prior art keywords
preparation
virus infection
immunization against
improved vaccines
tbe virus
Prior art date
Application number
FI953371A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI117974B (en
FI953371A0 (en
Inventor
Franz Xaver Heinz
Steven Allison
Christian Mandl
Christian Kunz
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT0135294A external-priority patent/AT402897B/en
Priority claimed from AT0087195A external-priority patent/AT405607B/en
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of FI953371A0 publication Critical patent/FI953371A0/en
Publication of FI953371A publication Critical patent/FI953371A/en
Application granted granted Critical
Publication of FI117974B publication Critical patent/FI117974B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24161—Methods of inactivation or attenuation
    • C12N2770/24162—Methods of inactivation or attenuation by genetic engineering
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Vaccine against flavivirus infections comprises nucleic acid encoding flavivirus proteins E and prM/M in full-length native form. Also claimed is a nucleic acid vector comprising the entire protein prM/M and E coding sequence of a flavivirus, provided that it is not an SV40-based plasmid vector.
FI953371A 1994-07-08 1995-07-07 An improved vaccine for immunization against TBE virus infections and a method for its preparation FI117974B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AT135294 1994-07-08
AT0135294A AT402897B (en) 1994-07-08 1994-07-08 Improved vaccine for immunization against tbe virus infections, and a process for its production
AT87195 1995-05-23
AT0087195A AT405607B (en) 1995-05-23 1995-05-23 Improved vaccine for immunizing against TBE virus infections, and a process for the preparation thereof

Publications (3)

Publication Number Publication Date
FI953371A0 FI953371A0 (en) 1995-07-07
FI953371A true FI953371A (en) 1996-01-09
FI117974B FI117974B (en) 2007-05-15

Family

ID=25594155

Family Applications (2)

Application Number Title Priority Date Filing Date
FI953371A FI117974B (en) 1994-07-08 1995-07-07 An improved vaccine for immunization against TBE virus infections and a method for its preparation
FI20070041A FI118222B (en) 1994-07-08 2007-01-17 Improved vaccine for immunization against Flavivirus infections

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI20070041A FI118222B (en) 1994-07-08 2007-01-17 Improved vaccine for immunization against Flavivirus infections

Country Status (9)

Country Link
EP (2) EP0691404B1 (en)
AT (2) ATE206459T1 (en)
CZ (1) CZ282927B6 (en)
DE (2) DE59508988D1 (en)
DK (2) DK0869184T3 (en)
ES (2) ES2155510T3 (en)
FI (2) FI117974B (en)
HU (2) HU219503B (en)
RU (1) RU2150294C1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69833388D1 (en) * 1997-11-20 2006-04-13 Us Army Medical Res Materiel C DNA VACCINES AGAINST TILE FLAVORS
US7425437B2 (en) 1999-11-26 2008-09-16 Crucell Holland B.V. Vaccines against West Nile Virus
NZ535690A (en) 2002-02-26 2009-04-30 Maxygen Inc Novel flavivirus antigens
AU2005318171B2 (en) 2004-12-20 2011-09-29 Crucell Holland B.V. Binding molecules capable of neutralizing West Nile virus and uses thereof
AU2006245734C1 (en) 2005-05-12 2012-05-24 Crucell Holland B.V. Host cell specific binding molecules capable of neutralizing viruses and uses thereof
CN103351435B (en) 2006-06-06 2015-08-19 克鲁塞尔荷兰公司 There is the human binding molecules and application thereof of killing activity against staphylococci
CA2960659C (en) 2007-11-09 2021-07-13 The Salk Institute For Biological Studies Use of tam receptor inhibitors as immunoenhancers and tam activators as immunosuppressors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3853693D1 (en) * 1987-03-20 1995-06-08 Immuno Ag TBE virus western subtype DNA and RNA molecules, polypeptides encoded by these molecules, and their use.
MY109299A (en) * 1990-08-15 1996-12-31 Virogenetics Corp Recombinant pox virus encoding flaviviral structural proteins
WO1992003161A1 (en) 1990-08-27 1992-03-05 The United States Of America, Represented By The Secretary, United States Department Of Commerce Flavivirus envelope proteins with increased immunogenicity for use in immunization against virus infection
JP3881689B2 (en) 1992-03-11 2007-02-14 パウダージェクト ヴァクシンズ，インコーポレイテッド Genetic vaccine for immunodeficiency virus

Also Published As

Publication number Publication date
EP0869184B1 (en) 2001-10-04
ES2165109T3 (en) 2002-03-01
EP0869184A3 (en) 1999-05-12
ES2155510T3 (en) 2001-05-16
FI118222B (en) 2007-08-31
ATE206459T1 (en) 2001-10-15
ATE198909T1 (en) 2001-02-15
CZ282927B6 (en) 1997-11-12
DE59509667D1 (en) 2001-11-08
DE59508988D1 (en) 2001-03-01
DK0691404T3 (en) 2001-03-19
HU9501832D0 (en) 1995-08-28
EP0691404B1 (en) 2001-01-24
FI117974B (en) 2007-05-15
EP0691404A2 (en) 1996-01-10
FI953371A0 (en) 1995-07-07
RU2150294C1 (en) 2000-06-10
EP0691404A3 (en) 1997-11-12
CZ176995A3 (en) 1996-01-17
HU219503B (en) 2001-04-28
DK0869184T3 (en) 2001-12-17
HU9903233D0 (en) 1999-11-29
HU224199B1 (en) 2005-06-28
HUT72395A (en) 1996-04-29
FI20070041A (en) 2007-01-17
EP0869184A2 (en) 1998-10-07

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