FI935658A - Nya selektiva aromatasinhiberande 4(5)-imidazoler - Google Patents

Nya selektiva aromatasinhiberande 4(5)-imidazoler Download PDF

Info

Publication number: FI935658A
Authority: FI; Finland
Prior art keywords: hiberande; aromatasin; imidazoler; nya; selective
Prior art date: 1991-06-18

Application number

FI935658A

Other languages

English (en)

Other versions

FI935658A0 (fi

Inventor

Arto Johannes Karjalainen

Marja-Liisa Soedervall

Arja Marketta Kalapudas

Reino Olavi Pelkonen

Aire Marja Laine

Risto Arvo Sakari Lammintausta

Jarmo Sakari Salonen

Original Assignee

Orion Yhtymae Oy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-06-18

Filing date

1993-12-16

Publication date

1993-12-16

1991-06-18 Priority claimed from GB919113142A external-priority patent/GB9113142D0/en

1993-12-16 Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy

1993-12-16 Publication of FI935658A publication Critical patent/FI935658A/fi

1993-12-16 Publication of FI935658A0 publication Critical patent/FI935658A0/fi

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Hematology (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

FI935658A 1991-06-18 1993-12-16 Nya selektiva aromatasinhiberande 4(5)-imidazoler FI935658A0 (fi)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB919113142A GB9113142D0 (en)	1991-06-18	1991-06-18	New selective aromatase inhibiting 4(5)-imidazoles
GB919125924A GB9125924D0 (en)	1991-06-18	1991-12-05	Stereoisomers of an imidazole derivative
PCT/FI1992/000184 WO1992022537A1 (en)	1991-06-18	1992-06-12	New selective aromatase inhibiting 4(5)-imidazoles

Publications (2)

Publication Number	Publication Date
FI935658A true FI935658A (fi)	1993-12-16
FI935658A0 FI935658A0 (fi)	1993-12-16

Family

ID=26299089

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI935658A FI935658A0 (fi)	1991-06-18	1993-12-16	Nya selektiva aromatasinhiberande 4(5)-imidazoler

Country Status (25)

Country	Link
US (1)	US5559141A (fi)
EP (1)	EP0589975A1 (fi)
JP (1)	JPH06508119A (fi)
KR (1)	KR940701386A (fi)
CN (1)	CN1068819A (fi)
AU (1)	AU665002B2 (fi)
BG (1)	BG98306A (fi)
CA (1)	CA2111469A1 (fi)
CZ (1)	CZ280293A3 (fi)
FI (1)	FI935658A0 (fi)
GB (1)	GB9125924D0 (fi)
HR (1)	HRP920170A2 (fi)
HU (1)	HUT67325A (fi)
IE (1)	IE921963A1 (fi)
IL (2)	IL102216A (fi)
LT (1)	LT3164B (fi)
LV (1)	LV10093B (fi)
MX (1)	MX9203000A (fi)
NO (1)	NO934688L (fi)
NZ (1)	NZ243139A (fi)
PT (1)	PT100604A (fi)
SI (1)	SI9200113A (fi)
SK (1)	SK144393A3 (fi)
TW (1)	TW206217B (fi)
WO (1)	WO1992022537A1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2273704B (en) *	1992-12-16	1997-01-22	Orion Yhtymae Oy	Triazolyl diaryl selective aromatase inhibiting compounds
SE9302333D0 (sv) *	1993-07-06	1993-07-06	Ab Astra	New compounds
US6080870A (en) *	1996-04-03	2000-06-27	Merck & Co., Inc.	Biaryl substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
US6063930A (en) *	1996-04-03	2000-05-16	Merck & Co., Inc.	Substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
AU716123B2 (en) *	1996-04-03	2000-02-17	Merck & Co., Inc.	Inhibitors of farnesyl-protein transferase
US6297239B1 (en) *	1997-10-08	2001-10-02	Merck & Co., Inc.	Inhibitors of prenyl-protein transferase
KR20030031132A (ko)	2000-07-28	2003-04-18	스미또모 세이야꾸 가부시키가이샤	피롤 유도체
JP4667384B2 (ja) *	2003-10-07	2011-04-13	レノビス，インコーポレイテッド	イオンチャネルリガンドとしてのアミド誘導体および薬学的組成物、ならびにこれらを使用する方法
BRPI0606365A2 (pt) *	2005-02-28	2017-06-27	Renovis Inc	composto ou um sal, solvato ou pró-droga farmaceuticamente aceitável do mesmo e estereoisômeros e tautômeros do mesmo, composição farmacêutica, métodos para prevenir, tratar, melhorar ou controlar uma doença ou condição e para preparar um composto, uso de um composto ou um sal, solvato ou composição farmaceuticamente aceitável do mesmo, método de tratamento de um mamífero, e, combinação
US7576099B2 (en)	2005-02-28	2009-08-18	Renovis, Inc.	Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
US7902247B2 (en) *	2008-01-09	2011-03-08	Allergan, Inc.	Substituted-aryl-2-phenylethyl-1H-imidazole compounds as subtype selective modulators of alpha 2B and/or alpha 2C adrenergic receptors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4605661A (en) *	1984-06-18	1986-08-12	Eli Lilly And Company	Aromastase inhibiting α,α-diarylimidazole-4(5)-propionitriles, α,α-diarylimidazole-4(5)-propionamides, and 4(5)-(2,2-diarylethyl)imidazoles
GB2210875B (en) *	1987-10-09	1991-05-29	Farmos Oy	Aromatase inhibiting 4(5)-imidazoles
GB2248058B (en) *	1990-09-21	1994-09-14	Orion Yhtymae Oy	Aromatase inhibiting 4(5)-imidazoles
US5439928A (en) *	1989-03-30	1995-08-08	Orion-Yhtyma Oy	Aromatase inhibiting 4(5)-imidazoles
AU627559B2 (en) *	1989-03-30	1992-08-27	Farmos-Yhtyma Oy	Novel aromatase inhibiting 4(5)-imidazoles

1991
- 1991-12-05 GB GB919125924A patent/GB9125924D0/en active Pending
1992
- 1992-06-12 KR KR1019930703934A patent/KR940701386A/ko not_active Application Discontinuation
- 1992-06-12 AU AU19783/92A patent/AU665002B2/en not_active Ceased
- 1992-06-12 CA CA002111469A patent/CA2111469A1/en not_active Abandoned
- 1992-06-12 CZ CS932802A patent/CZ280293A3/cs unknown
- 1992-06-12 WO PCT/FI1992/000184 patent/WO1992022537A1/en not_active Application Discontinuation
- 1992-06-12 US US08/167,873 patent/US5559141A/en not_active Expired - Fee Related
- 1992-06-12 SK SK1443-93A patent/SK144393A3/sk unknown
- 1992-06-12 EP EP92912309A patent/EP0589975A1/en not_active Withdrawn
- 1992-06-12 JP JP4511061A patent/JPH06508119A/ja active Pending
- 1992-06-15 LV LVP-92-29A patent/LV10093B/en unknown
- 1992-06-15 NZ NZ243139A patent/NZ243139A/en unknown
- 1992-06-16 IL IL10221692A patent/IL102216A/en not_active IP Right Cessation
- 1992-06-17 HR HR920170A patent/HRP920170A2/hr not_active Application Discontinuation
- 1992-06-17 TW TW081104752A patent/TW206217B/zh active
- 1992-06-17 PT PT100604A patent/PT100604A/pt not_active Application Discontinuation
- 1992-06-18 CN CN92105664A patent/CN1068819A/zh active Pending
- 1992-06-18 SI SI19929200113A patent/SI9200113A/sl unknown
- 1992-06-18 MX MX9203000A patent/MX9203000A/es unknown
- 1992-07-01 IE IE196392A patent/IE921963A1/en not_active Application Discontinuation
- 1992-08-28 LT LTIP175A patent/LT3164B/lt not_active IP Right Cessation
1993
- 1993-12-16 FI FI935658A patent/FI935658A0/fi not_active Application Discontinuation
- 1993-12-17 HU HU9303653A patent/HUT67325A/hu active IP Right Revival
- 1993-12-17 BG BG98306A patent/BG98306A/bg unknown
- 1993-12-17 NO NO934688A patent/NO934688L/no unknown
1995
- 1995-09-27 IL IL11543995A patent/IL115439A0/xx unknown

Also Published As

Publication number	Publication date
SI9200113A (en)	1992-12-31
IE921963A1 (en)	1992-12-30
IL115439A0 (en)	1995-12-31
WO1992022537A1 (en)	1992-12-23
LT3164B (en)	1995-02-27
HU9303653D0 (en)	1994-04-28
BG98306A (bg)	1994-08-30
MX9203000A (es)	1993-02-01
HUT67325A (en)	1995-03-28
JPH06508119A (ja)	1994-09-14
NO934688D0 (no)	1993-12-17
GB9125924D0 (en)	1992-02-05
AU1978392A (en)	1993-01-12
AU665002B2 (en)	1995-12-14
CZ280293A3 (en)	1994-05-18
LV10093B (en)	1995-02-20
HRP920170A2 (en)	1994-08-31
FI935658A0 (fi)	1993-12-16
US5559141A (en)	1996-09-24
NZ243139A (en)	1994-08-26
NO934688L (no)	1993-12-17
CA2111469A1 (en)	1992-12-23
LV10093A (lv)	1994-05-10
PT100604A (pt)	1993-10-29
CN1068819A (zh)	1993-02-10
EP0589975A1 (en)	1994-04-06
IL102216A0 (en)	1993-01-14
LTIP175A (lt)	1994-08-25
SK144393A3 (en)	1994-11-09
TW206217B (fi)	1993-05-21
KR940701386A (ko)	1994-05-28
IL102216A (en)	1996-06-18

Legal Events

Date	Code	Title	Description
1998-01-09	FD	Application lapsed

Publication	Publication Date	Title
FI924557A (fi)	1993-04-10	Nya fenylpyrazolfungicider
FI924077A (fi)	1993-03-13	Nya omaettade acykliska purin- och pyrimidinfosfonatderivat
FI921135A (fi)	1992-09-22	Nya karbonsyraamider
FI933451A (fi)	1993-08-03	Nya steroidestrar
FI934128A (fi)	1993-09-21	Nya inkapslade material
FI930381A (fi)	1993-03-26	Nya vaermestabila pullulanaser
FI933450A0 (fi)	1993-08-03	Nya steroider
FI924672A (fi)	1992-10-15	Nya antimikrobiella kinolontioureas
FI933285A (fi)	1994-01-23	Nya herbicider
FI925086A0 (fi)	1992-11-09	Nya hybrid-vaextfaktorer
FI921614A (fi)	1992-10-12	Nya herbicider
FI923872A (fi)	1993-03-01	Nya bensopyranderivat
FI923762A (fi)	1992-08-20	Nya heparinderivat
FI932928A (fi)	1993-06-24	Nya bensodiazepinderivat
FI935658A (fi)	1993-12-16	Nya selektiva aromatasinhiberande 4(5)-imidazoler
FI935494A (fi)	1993-12-08	Nya amidolakyl- och imidoalkylpiperaziner
FI930495A (fi)	1993-09-13	Nya herbicider
FI931585A (fi)	1993-10-09	Nya fungicida triazol- och imidazolderivat
FI922552A (fi)	1992-12-08	Nya kefemfoereningar
FI932511A (fi)	1993-12-04	Nya tiosemikarbazonderivat
FI930139A (fi)	1993-07-15	Nya herbicider
FI933155A (fi)	1994-01-12	Nya kylmedelssammansaettningar
FI925722A (fi)	1993-06-19	Nya tiazoler
FI925755A (fi)	1993-06-28	Framstaellningsfoerfarande av nya bensofuranylimidazolderivat
FI925679A (fi)	1993-06-19	Nya imidazoler