FI923286A - KELATERINGSAEMNEN. - Google Patents
KELATERINGSAEMNEN. Download PDFInfo
- Publication number
- FI923286A FI923286A FI923286A FI923286A FI923286A FI 923286 A FI923286 A FI 923286A FI 923286 A FI923286 A FI 923286A FI 923286 A FI923286 A FI 923286A FI 923286 A FI923286 A FI 923286A
- Authority
- FI
- Finland
- Prior art keywords
- kelateringsaemnen
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/228—Host-guest complexes, clathrates, chelates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Nanotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Crystallography & Structural Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Acoustics & Sound (AREA)
- Molecular Biology (AREA)
- Optics & Photonics (AREA)
- Biophysics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909001245A GB9001245D0 (en) | 1990-01-19 | 1990-01-19 | Compounds |
PCT/EP1991/000126 WO1991010645A2 (en) | 1990-01-19 | 1991-01-18 | Chelants |
Publications (2)
Publication Number | Publication Date |
---|---|
FI923286A true FI923286A (en) | 1992-07-17 |
FI923286A0 FI923286A0 (en) | 1992-07-17 |
Family
ID=10669570
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI923286A FI923286A0 (en) | 1990-01-19 | 1992-07-17 | KELATERINGSAEMNEN. |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0527131A1 (en) |
JP (1) | JPH05506426A (en) |
AU (1) | AU7060291A (en) |
CA (1) | CA2074171A1 (en) |
FI (1) | FI923286A0 (en) |
GB (1) | GB9001245D0 (en) |
HU (1) | HUT61306A (en) |
IE (1) | IE910189A1 (en) |
NO (1) | NO922849L (en) |
WO (1) | WO1991010645A2 (en) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5334371A (en) * | 1988-07-20 | 1994-08-02 | Schering Aktiengesellschaft | Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI |
FR2644785B1 (en) * | 1989-03-24 | 1991-07-05 | Guerbet Sa | NOVEL NITROGEN MACROCYCLIC LIGANDS, PROCESS FOR THEIR PREPARATION, METAL COMPLEXES FORMED BY SUCH LIGANDS AND DIAGNOSTIC COMPOSITION CONTAINING THEM |
US5367080A (en) * | 1990-11-08 | 1994-11-22 | Sterling Winthrop Inc. | Complexing agents and targeting radioactive immunoreagents useful in therapeutic and diagnostic imaging compositions and methods |
CA2072934C (en) * | 1991-07-19 | 2007-08-28 | Karl William Aston | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
WO1994026313A1 (en) * | 1993-05-06 | 1994-11-24 | The Dow Chemical Company | Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as contrast agents |
DE69223504T2 (en) * | 1991-12-10 | 1998-04-02 | The Dow Chemical Co., Midland, Mich. | Bicycloazamacrocyclophosphonic acid, complexes, conjugates, contrast agents and preparation |
IL104059A0 (en) * | 1991-12-10 | 1993-05-13 | Dow Chemical Co | Bicyclopolyazamacrocyclocarboxylic acid complexes,their conjugates,processes for their preparation,and use as contrast agents |
US5739294A (en) * | 1991-12-10 | 1998-04-14 | The Dow Chemical Company | Bicyclopol yazamacrocyclophosphonic acid complexes for use as contrast agents |
JPH07502044A (en) * | 1991-12-10 | 1995-03-02 | ザ ダウ ケミカル カンパニー | Oral composition for inhibiting plaque and tartar formation |
US5428139A (en) * | 1991-12-10 | 1995-06-27 | The Dow Chemical Company | Bicyclopolyazamacrocyclophosphonic acid complexes for use as radiopharmaceuticals |
RU2122431C1 (en) * | 1992-05-07 | 1998-11-27 | Никомед Имеджинг Ас | Radioactive immunoreagent of the directed effect, a composition for obtaining an image of malignant neoplasm in body, a method of obtaining an image and a chelating agent |
AU4237493A (en) * | 1993-05-06 | 1994-12-12 | Dow Chemical Company, The | Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as radiopharmaceuticals |
WO1994026755A1 (en) * | 1993-05-06 | 1994-11-24 | The Dow Chemical Company | Bicyclopolyazamacrocyclophosphonic acid complexes, a process for their preparation, and their conjugates, for use as radiopharmaceuticals |
JPH08509976A (en) * | 1993-05-06 | 1996-10-22 | ザ・ダウ・ケミカル・カンパニー | Bicyclopolyaza macrocyclophosphonic acids for use as contrast agents, complexes and composites thereof and processes for their preparation |
US5476644A (en) * | 1994-04-13 | 1995-12-19 | Sterling Winthrop Inc. | Cyclic triamine chelating agents |
US6207826B1 (en) | 1995-03-27 | 2001-03-27 | Isis Pharmaceuticals, Inc. | Macrocyclic compounds having nitrogen-containing linkages |
WO1996030377A1 (en) * | 1995-03-27 | 1996-10-03 | Isis Pharmaceuticals, Inc. | Nitrogenous macrocyclic compounds |
US6525041B1 (en) | 1995-06-06 | 2003-02-25 | Pharmacia Corporation | Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
EP0844889A1 (en) * | 1995-08-17 | 1998-06-03 | Monsanto Company | Methods of diagnostic image analysis using metal complexes of nitrogen-containing macrocyclic ligands |
JPH11511168A (en) | 1995-08-17 | 1999-09-28 | モンサント カンパニー | Diagnostic imaging method using biomolecule conjugate of metal complex of nitrogen-containing macrocyclic ligand |
GB9702978D0 (en) * | 1997-02-13 | 1997-04-02 | Ciba Geigy | Compounds |
US6214817B1 (en) | 1997-06-20 | 2001-04-10 | Monsanto Company | Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity |
CA2665984C (en) | 2006-10-12 | 2017-02-28 | Activbiotics, Inc. | Superoxide dismutase mimetics for the treatment of oral mucositis |
US20090208421A1 (en) | 2008-02-19 | 2009-08-20 | Dominique Meyer | Process for preparing a pharmaceutical formulation of contrast agents |
US9149483B2 (en) | 2011-09-26 | 2015-10-06 | Galera Labs, Llc | Methods for treatment of diseases |
HUE033219T2 (en) * | 2013-04-26 | 2017-11-28 | Guerbet Sa | Contrast medium formulation and related preparation method |
WO2017027728A1 (en) | 2015-08-11 | 2017-02-16 | Galera Labs, Llc | Pentaaza macrocyclic ring complexes possessing oral bioavailability |
GB201610738D0 (en) | 2016-06-20 | 2016-08-03 | Ge Healthcare As | Chelate compounds |
IL295620B2 (en) | 2017-04-13 | 2024-01-01 | Galera Labs Llc | Combination cancer immunotherapy with pentaaza macrocyclic ring complex |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2751390A (en) * | 1950-09-02 | 1956-06-19 | Dow Chemical Co | Di-pyridyl aliphatic alkylene polyamine poly acids |
US4899755A (en) * | 1985-05-08 | 1990-02-13 | The General Hospital Corporation | Hepatobiliary NMR contrast agents |
CA1340527C (en) * | 1988-05-31 | 1999-05-04 | Lidia Vallarino | Macrocyclic complexes of yttrium, the lanthanides and the actinides having peripheral coupling functionalities |
DE3825040A1 (en) * | 1988-07-20 | 1990-01-25 | Schering Ag, 13353 Berlin | 5- OR 6-RING MACROCYCLIC POLYAZA COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENTS CONTAINING THEM |
FR2644785B1 (en) * | 1989-03-24 | 1991-07-05 | Guerbet Sa | NOVEL NITROGEN MACROCYCLIC LIGANDS, PROCESS FOR THEIR PREPARATION, METAL COMPLEXES FORMED BY SUCH LIGANDS AND DIAGNOSTIC COMPOSITION CONTAINING THEM |
-
1990
- 1990-01-19 GB GB909001245A patent/GB9001245D0/en active Pending
-
1991
- 1991-01-18 JP JP91502458A patent/JPH05506426A/en active Pending
- 1991-01-18 CA CA002074171A patent/CA2074171A1/en not_active Abandoned
- 1991-01-18 WO PCT/EP1991/000126 patent/WO1991010645A2/en not_active Application Discontinuation
- 1991-01-18 HU HU922347A patent/HUT61306A/en unknown
- 1991-01-18 EP EP91902213A patent/EP0527131A1/en not_active Withdrawn
- 1991-01-18 AU AU70602/91A patent/AU7060291A/en not_active Abandoned
- 1991-01-21 IE IE018991A patent/IE910189A1/en unknown
-
1992
- 1992-07-17 NO NO92922849A patent/NO922849L/en unknown
- 1992-07-17 FI FI923286A patent/FI923286A0/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HUT61306A (en) | 1992-12-28 |
GB9001245D0 (en) | 1990-03-21 |
JPH05506426A (en) | 1993-09-22 |
WO1991010645A2 (en) | 1991-07-25 |
WO1991010645A3 (en) | 1991-12-26 |
IE910189A1 (en) | 1991-07-31 |
AU7060291A (en) | 1991-08-05 |
NO922849D0 (en) | 1992-07-17 |
EP0527131A1 (en) | 1993-02-17 |
CA2074171A1 (en) | 1991-07-20 |
FI923286A0 (en) | 1992-07-17 |
HU9202347D0 (en) | 1992-10-28 |
NO922849L (en) | 1992-09-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |