FI920271A0 - Polyamintioler som straolningsskyddande aemnen. - Google Patents
Polyamintioler som straolningsskyddande aemnen.Info
- Publication number
- FI920271A0 FI920271A0 FI920271A FI920271A FI920271A0 FI 920271 A0 FI920271 A0 FI 920271A0 FI 920271 A FI920271 A FI 920271A FI 920271 A FI920271 A FI 920271A FI 920271 A0 FI920271 A0 FI 920271A0
- Authority
- FI
- Finland
- Prior art keywords
- spo3h2
- straolningsskyddande
- polyamintioler
- aemnen
- som
- Prior art date
Links
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000718 radiation-protective agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/33—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring
- C07C323/34—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring the thio group being a mercapto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
- C07F9/165—Esters of thiophosphoric acids
- C07F9/1651—Esters of thiophosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polyurethanes Or Polyureas (AREA)
- Materials For Medical Uses (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polyethers (AREA)
- Display Devices Of Pinball Game Machines (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/644,810 US5217964A (en) | 1991-01-23 | 1991-01-23 | Polyamine thiols as radioprotective agents |
US64481091 | 1991-01-23 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI920271A0 true FI920271A0 (fi) | 1992-01-22 |
FI920271A FI920271A (fi) | 1992-07-24 |
FI111251B FI111251B (fi) | 2003-06-30 |
Family
ID=24586432
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI920271A FI111251B (fi) | 1991-01-23 | 1992-01-22 | Menetelmä säteilyltä suojaavien polyamiinitiolien valmistamiseksi |
Country Status (16)
Country | Link |
---|---|
US (1) | US5217964A (fi) |
EP (1) | EP0497202B1 (fi) |
JP (1) | JP3203582B2 (fi) |
KR (1) | KR100195420B1 (fi) |
AT (1) | ATE127785T1 (fi) |
AU (1) | AU647570B2 (fi) |
CA (1) | CA2059817C (fi) |
DE (1) | DE69204698T2 (fi) |
ES (1) | ES2079695T3 (fi) |
FI (1) | FI111251B (fi) |
IE (1) | IE67961B1 (fi) |
IL (1) | IL100698A (fi) |
NO (1) | NO179003C (fi) |
NZ (1) | NZ241347A (fi) |
PT (1) | PT100045B (fi) |
ZA (1) | ZA92360B (fi) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5677351A (en) * | 1986-12-02 | 1997-10-14 | University Of Florida Research Foundation, Inc. | Sterically hindered tetraamines and method for their production |
US5393757A (en) * | 1986-12-02 | 1995-02-28 | University Of Florida | Polyamines and anti-diarrheal and gastrointestinal anti-spasmodic pharmaceutical compositions and methods of treatment |
US5342945A (en) * | 1986-12-02 | 1994-08-30 | University Of Florida Research Foundation, Inc. | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives |
US5354782A (en) * | 1991-01-17 | 1994-10-11 | Merrell Dow Pharmaceuticals Inc. | Polyamine phenols as radioprotective agents |
US5488042A (en) * | 1992-03-13 | 1996-01-30 | Arch Development Corporation | Method for protection against genotoxic mutagenesis |
KR100311851B1 (ko) * | 1993-02-23 | 2002-04-24 | 슈테펜엘.네스비트 | 방사선보호제로서의폴리아민유도체 |
WO1994027961A1 (en) * | 1993-05-26 | 1994-12-08 | Merrell Dow Pharmaceutials Inc. | N-alkylthio polyamine derivatives as radioprotective agents |
US5994409A (en) * | 1997-12-09 | 1999-11-30 | U.S. Bioscience, Inc. | Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds |
US6482943B1 (en) * | 1999-04-30 | 2002-11-19 | Slil Biomedical Corporation | Quinones as disease therapies |
IL146126A0 (en) * | 1999-04-30 | 2002-07-25 | Slil Biomedical Corp | Novel polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases |
BR0010701A (pt) * | 1999-04-30 | 2002-02-13 | Slil Biomedical Corp | Análogos de poliamina restritos de forma conformacional como terapias de doenças |
US6649587B1 (en) | 1999-04-30 | 2003-11-18 | Slil Biomedical Corporation | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases |
US6489312B1 (en) * | 1999-06-15 | 2002-12-03 | Medimmune Oncology, Inc. | Pharmaceutical formulations comprising aminoalkyl phosphorothioates |
WO2001085142A1 (en) * | 2000-05-05 | 2001-11-15 | Wisconsin Alumni Research Foundation | Compositions and methods for protecting cells during cancer chemotherapy and radiotherapy |
EP1337504A4 (en) * | 2000-11-08 | 2005-10-05 | Cellgate Inc | NOVEL AMINO ACID CONJUGATES AND POLYAMINE ANALOGUES USEFUL AS ANTICANCING AGENTS |
US7053072B2 (en) | 2001-05-11 | 2006-05-30 | Medimmune Oncology, Inc. | Methods for the administration of amifostine and related compounds |
WO2003013245A1 (en) * | 2001-08-07 | 2003-02-20 | Wisconsin Alumni Research Foundation | Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy |
MXPA04005509A (es) | 2001-12-07 | 2004-12-06 | Slil Biomedical Corp | Poliaminas sustituidas con cicloalquilo para terapia de cancer y metodos de sintesis de las mismas. |
CN1642902A (zh) * | 2002-02-07 | 2005-07-20 | 威斯康星校友研究基金会 | 与癌治疗联合使用的聚胺化合物及组合物 |
WO2005014524A2 (en) * | 2003-08-07 | 2005-02-17 | Wisconsin Alumni Research Foundation | Amino thiol compounds and compositions for use in conjunction with cancer therapy |
WO2007149484A2 (en) * | 2006-06-20 | 2007-12-27 | Dana-Farber Cancer Institute | Inhibitors of usp1 deubiquitinating enzyme complex |
CA2797719C (en) | 2010-04-30 | 2019-11-26 | Dana-Farber Cancer Institute, Inc. | Small molecule inhibitors of usp1 deubiquitinating enzyme activity |
US9725425B1 (en) | 2014-02-25 | 2017-08-08 | Dana-Farber Cancer Institute, Inc. | Compounds and methods for treating cancer |
TWM528362U (zh) * | 2016-04-15 | 2016-09-11 | Calendar Entpr Co Ltd | 無繩式電動節能捲簾結構改良 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2901503A (en) * | 1956-08-28 | 1959-08-25 | Campbell Pharmaceuticals Inc | Dialkylaminophenyl esters of thiophosphoric acids |
US3368972A (en) * | 1965-01-06 | 1968-02-13 | Mobil Oil Corp | High molecular weight mannich bases as engine oil additives |
ZA88600B (en) * | 1987-02-03 | 1988-07-28 | Merrell Dow Pharmaceuticals Inc. | Novel polyamine derivatives |
ZA887410B (en) * | 1987-10-08 | 1989-06-28 | Merrell Dow Pharma | Polyamine derivatives as antineoplastic agents |
-
1991
- 1991-01-23 US US07/644,810 patent/US5217964A/en not_active Expired - Fee Related
-
1992
- 1992-01-17 ZA ZA92360A patent/ZA92360B/xx unknown
- 1992-01-17 AU AU10304/92A patent/AU647570B2/en not_active Ceased
- 1992-01-19 IL IL10069892A patent/IL100698A/en not_active IP Right Cessation
- 1992-01-21 NZ NZ241347A patent/NZ241347A/en unknown
- 1992-01-22 EP EP92101017A patent/EP0497202B1/en not_active Expired - Lifetime
- 1992-01-22 NO NO920283A patent/NO179003C/no unknown
- 1992-01-22 AT AT92101017T patent/ATE127785T1/de not_active IP Right Cessation
- 1992-01-22 DE DE69204698T patent/DE69204698T2/de not_active Expired - Fee Related
- 1992-01-22 KR KR1019920000836A patent/KR100195420B1/ko not_active IP Right Cessation
- 1992-01-22 IE IE920189A patent/IE67961B1/en not_active IP Right Cessation
- 1992-01-22 CA CA002059817A patent/CA2059817C/en not_active Expired - Fee Related
- 1992-01-22 PT PT100045A patent/PT100045B/pt not_active IP Right Cessation
- 1992-01-22 FI FI920271A patent/FI111251B/fi active
- 1992-01-22 ES ES92101017T patent/ES2079695T3/es not_active Expired - Lifetime
- 1992-01-23 JP JP03128092A patent/JP3203582B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0497202B1 (en) | 1995-09-13 |
KR100195420B1 (ko) | 1999-06-15 |
DE69204698T2 (de) | 1996-02-15 |
NO920283D0 (no) | 1992-01-22 |
EP0497202A1 (en) | 1992-08-05 |
AU1030492A (en) | 1992-07-30 |
NO179003B (no) | 1996-04-09 |
AU647570B2 (en) | 1994-03-24 |
NZ241347A (en) | 1994-04-27 |
JP3203582B2 (ja) | 2001-08-27 |
ZA92360B (en) | 1992-11-25 |
US5217964A (en) | 1993-06-08 |
IE67961B1 (en) | 1996-05-15 |
PT100045A (pt) | 1993-03-31 |
FI920271A (fi) | 1992-07-24 |
IE920189A1 (en) | 1992-07-29 |
NO920283L (no) | 1992-07-24 |
CA2059817A1 (en) | 1992-07-24 |
ES2079695T3 (es) | 1996-01-16 |
CA2059817C (en) | 2003-07-15 |
FI111251B (fi) | 2003-06-30 |
KR920014772A (ko) | 1992-08-25 |
DE69204698D1 (de) | 1995-10-19 |
IL100698A (en) | 1998-08-16 |
ATE127785T1 (de) | 1995-09-15 |
NO179003C (no) | 1996-07-17 |
IL100698A0 (en) | 1992-09-06 |
JPH04334362A (ja) | 1992-11-20 |
PT100045B (pt) | 1999-10-29 |
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