FI913658A - 4-amino-d4,6-steroider och deras anvaendning som 5a-reduktas-inhibitorer. - Google Patents

4-amino-d4,6-steroider och deras anvaendning som 5a-reduktas-inhibitorer. Download PDF

Info

Publication number: FI913658A
Authority: FI; Finland
Prior art keywords: amino; steroider; inhibitorer; reductas; deras anvaendning
Prior art date: 1990-08-01

Application number

FI913658A

Other languages

English (en)

Other versions

FI102378B (fi

FI102378B1 (fi

FI913658A0 (fi

Inventor

Philip Marvin Weintraub

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-01

Filing date

1991-07-31

Publication date

1992-02-02

1991-03-19 Priority claimed from US07/671,555 external-priority patent/US5143909A/en

1991-07-02 Priority claimed from US07/720,899 external-priority patent/US5130424A/en

1991-07-31 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1991-07-31 Publication of FI913658A0 publication Critical patent/FI913658A0/fi

1992-02-02 Publication of FI913658A publication Critical patent/FI913658A/fi

1998-11-30 Application granted granted Critical

1998-11-30 Publication of FI102378B publication Critical patent/FI102378B/fi

1998-11-30 Publication of FI102378B1 publication Critical patent/FI102378B1/fi

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0011—Unsubstituted amino radicals

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Dermatology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

FI913658A 1990-08-01 1991-07-31 Menetelmä terapeuttisesti käyttökelpoisten 4-amino- 4,6-steroidien valmistamiseksi FI102378B1 (fi)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US56141090A	1990-08-01	1990-08-01
US56141090		1990-08-01
US67155591		1991-03-19
US07/671,555 US5143909A (en)	1991-03-19	1991-03-19	Aminosteroids in a method for inhibiting c17-20 lyase
US07/720,899 US5130424A (en)	1990-08-01	1991-07-02	4-amino-delta-4,6-steroids and their use as 5 alpha-reductase inhibitors
US72089991		1991-07-02

Publications (4)

Publication Number	Publication Date
FI913658A0 FI913658A0 (fi)	1991-07-31
FI913658A true FI913658A (fi)	1992-02-02
FI102378B FI102378B (fi)	1998-11-30
FI102378B1 FI102378B1 (fi)	1998-11-30

Family

ID=27415853

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI913658A FI102378B1 (fi)	1990-08-01	1991-07-31	Menetelmä terapeuttisesti käyttökelpoisten 4-amino- 4,6-steroidien valmistamiseksi

Country Status (17)

Country	Link
EP (1)	EP0469547B1 (fi)
JP (1)	JP3021818B2 (fi)
CN (1)	CN1031574C (fi)
AT (1)	ATE138073T1 (fi)
AU (1)	AU642757B2 (fi)
CA (1)	CA2048243C (fi)
DE (1)	DE69119502T2 (fi)
DK (1)	DK0469547T3 (fi)
ES (1)	ES2089063T3 (fi)
FI (1)	FI102378B1 (fi)
GR (1)	GR3020268T3 (fi)
HU (1)	HU210042B (fi)
IE (1)	IE75199B1 (fi)
IL (1)	IL98998A (fi)
NO (1)	NO180197C (fi)
NZ (1)	NZ239141A (fi)
PT (1)	PT98519B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH07502511A (ja) *	1991-12-20	1995-03-16	グラクソ、インコーポレーテッド	５‐α‐テストステロンレダクターゼ阻害剤
US5302589A (en) *	1992-08-07	1994-04-12	Glaxo, Inc.	Heterocyclic inhibitors of 5-α-testosterone reductase
US5486511A (en) *	1993-05-25	1996-01-23	Merrell Dow Pharmaceuticals Inc.	4-amino-17β-(cyclopropyloxy)androst-4-en-3-one, 4-amino-17β-(cyclopropylamino)androst-4-en-3-one and related compounds as C17-20 lyase and 5α-reductase
TW369521B (en) *	1993-09-17	1999-09-11	Smithkline Beecham Corp	Androstenone derivative
US5356935A (en) *	1993-12-13	1994-10-18	Eli Lilly And Company	Reduced phenanthrenes
WO1995029932A1 (en) *	1994-05-02	1995-11-09	Merrell Pharmaceuticals Inc.	Process for the preparation of 4-amino-δ4-3-ketosteroids via 4-nitro-δ4-3-ketosteroids
US5541322A (en) *	1994-10-14	1996-07-30	Glaxo Wellcome Inc.	Synthesis of 6-azaandrostenones
AU6087700A (en) *	1999-07-15	2001-02-05	Procter & Gamble Company, The	Nitrogen-containing steroid compounds and their use to regulate hair growth
JP6353939B1 (ja) *	2017-02-15	2018-07-04	横関油脂工業株式会社	油状組成物、その製法、油性基剤および皮膚外用剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1154008A (en) *	1979-05-02	1983-09-20	Thomas R. Blohm	STEROID 5.alpha.-REDUCTASE INHIBITORS
GB8503940D0 (en) *	1985-02-15	1985-03-20	Erba Farmitalia	4-substituted androstendione derivatives

1991
- 1991-07-26 AU AU81356/91A patent/AU642757B2/en not_active Ceased
- 1991-07-26 NZ NZ239141A patent/NZ239141A/en unknown
- 1991-07-29 IL IL9899891A patent/IL98998A/en active IP Right Grant
- 1991-07-30 ES ES91112795T patent/ES2089063T3/es not_active Expired - Lifetime
- 1991-07-30 DE DE69119502T patent/DE69119502T2/de not_active Expired - Fee Related
- 1991-07-30 DK DK91112795.9T patent/DK0469547T3/da active
- 1991-07-30 EP EP91112795A patent/EP0469547B1/en not_active Expired - Lifetime
- 1991-07-30 AT AT91112795T patent/ATE138073T1/de not_active IP Right Cessation
- 1991-07-31 IE IE270691A patent/IE75199B1/en not_active IP Right Cessation
- 1991-07-31 CA CA002048243A patent/CA2048243C/en not_active Expired - Fee Related
- 1991-07-31 PT PT98519A patent/PT98519B/pt not_active IP Right Cessation
- 1991-07-31 NO NO912982A patent/NO180197C/no not_active IP Right Cessation
- 1991-07-31 HU HU912559A patent/HU210042B/hu not_active IP Right Cessation
- 1991-07-31 FI FI913658A patent/FI102378B1/fi active
- 1991-08-01 CN CN91105278A patent/CN1031574C/zh not_active Expired - Fee Related
- 1991-08-01 JP JP3214162A patent/JP3021818B2/ja not_active Expired - Lifetime
1996
- 1996-06-19 GR GR960401647T patent/GR3020268T3/el unknown

Also Published As

Publication number	Publication date
HU912559D0 (en)	1992-01-28
PT98519B (pt)	1999-01-29
PT98519A (pt)	1992-06-30
JPH05320189A (ja)	1993-12-03
AU642757B2 (en)	1993-10-28
NO912982L (no)	1992-02-03
GR3020268T3 (en)	1996-09-30
CA2048243A1 (en)	1992-02-02
ES2089063T3 (es)	1996-10-01
CA2048243C (en)	2003-04-08
IE75199B1 (en)	1997-08-27
IL98998A0 (en)	1992-07-15
IL98998A (en)	1996-01-19
CN1031574C (zh)	1996-04-17
CN1059150A (zh)	1992-03-04
DE69119502T2 (de)	1996-09-26
NO180197B (no)	1996-11-25
DK0469547T3 (da)	1996-06-10
ATE138073T1 (de)	1996-06-15
FI102378B (fi)	1998-11-30
FI102378B1 (fi)	1998-11-30
AU8135691A (en)	1992-02-06
FI913658A0 (fi)	1991-07-31
EP0469547A2 (en)	1992-02-05
NZ239141A (en)	1994-04-27
HUT59157A (en)	1992-04-28
JP3021818B2 (ja)	2000-03-15
NO912982D0 (no)	1991-07-31
DE69119502D1 (de)	1996-06-20
IE912706A1 (en)	1992-02-12
EP0469547B1 (en)	1996-05-15
EP0469547A3 (en)	1992-06-03
HU210042B (en)	1995-01-30
NO180197C (no)	1997-03-05

Publication	Publication Date	Title
NO940595L (no)	1994-08-23	Cykliske derivater, legemidler som inneholder disse forbindelsene og fremgangsmåte ved deres fremstilling
KR840005718A (ko)	1984-11-15	오메프라졸 중간체의 제조방법
FI913658A (fi)	1992-02-02	4-amino-d4,6-steroider och deras anvaendning som 5a-reduktas-inhibitorer.
FI913657A (fi)	1992-02-02	4-amino-d4-steroider och deras anvaendning som 5a-reduktasinhibitorer.
ATE11544T1 (de)	1985-02-15	Brom substituierte derivate von sucrose.
DK0613896T3 (da)	1999-04-26	Fremgangsmåde til fremstilling af sulfonylurinstofderivater
DK305184A (da)	1984-12-24	Hexahydropyrrolo(2,1-a)isoquinolin-derivater
IE41394L (en)	1976-01-01	Benzimidazole derivatives
DE69839315D1 (de)	2008-05-08	Verfahren zur Herstellung von einer halogenierten Verbindung
ATE19065T1 (de)	1986-04-15	Verfahren zur herstellung von 1-(4-chlorbenzoyl)5-methoxy-2-methyl-3-indolacetoxyessigs\|ure.
KR970061898A (ko)	1997-09-12	세팔로스포린 중간체의 제조방법
KR970061899A (ko)	1997-09-12	3-할로메틸-3-세펨-4-카르복실레이트 1-옥사이드의 신규 제조방법
JPS6431761A (en)	1989-02-02	Polyhalogenoindoline derivative
KR970061895A (ko)	1997-09-12	3-할로메틸-3-세펨의 신규 제조 방법
KR940018364A (ko)	1994-08-16	신규한 엔(n)-아릴설포닐-2-이미다졸리디논 유도체 및 그의 제조방법
KR880000445A (ko)	1988-03-25	7-아미노-3-알콕시메틸-3-세펨-4-카복실산 유도체의 제조방법
TH3434A (th)	1986-08-01	สารกึ่งสำเร็จจำพวกกรดเบนโซอิก ชนิดถูกแทนที่ (3ที่)
TH13109EX (th)	1993-09-10	อนุพันธ์ของกรดคาร์บอกซิลิคที่ถูกแทนที่
FI863897A (fi)	1988-03-27	Kemiskt foerfarande.
JPS5589286A (en)	1980-07-05	Novel preparation of 3-hydrazonomethylrifamycins
KR960037689A (ko)	1996-11-19	p-메톡시 벤질보호기를 갖는 세펨유도체의 선택적인 탈보호 방법