FI896249A0 - Menetelmä terapeuttisesti käyttökelpoisten 7-oksabisykloheptyylisubstituoitujen heterosyklisten amidiprostaglandiinijohdannaisten valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten 7-oksabisykloheptyylisubstituoitujen heterosyklisten amidiprostaglandiinijohdannaisten valmistamiseksi

Info

Publication number: FI896249A0
Authority: FI; Finland
Prior art keywords: oxabicycloheptyl; preparation; substituted heterocyclic; therapeutically useful; prostaglandin derivatives
Prior art date: 1988-12-23

Application number

FI896249A

Other languages

English (en)

Swedish (sv)

Other versions

FI97230C (fi

FI97230B (fi

Inventor

Philip M Sher

Philip D Stein

David Floyd

Steven E Hall

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-23

Filing date

1989-12-22

Publication date

1989-12-22

1989-12-22 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1989-12-22 Publication of FI896249A0 publication Critical patent/FI896249A0/fi

1996-07-31 Application granted granted Critical

1996-07-31 Publication of FI97230B publication Critical patent/FI97230B/fi

1996-11-11 Publication of FI97230C publication Critical patent/FI97230C/fi

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

FI896249A 1988-12-23 1989-12-22 Menetelmä terapeuttisesti käyttökelpoisten 7-oksabisykloheptyylisubstituoitujen heterosyklisten amidiprostaglandiinijohdannaisten valmistamiseksi FI97230C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US28882688A	1988-12-23	1988-12-23
US28882688		1988-12-23

Publications (3)

Publication Number	Publication Date
FI896249A0 true FI896249A0 (fi)	1989-12-22
FI97230B FI97230B (fi)	1996-07-31
FI97230C FI97230C (fi)	1996-11-11

Family

ID=23108806

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI896249A FI97230C (fi)	1988-12-23	1989-12-22	Menetelmä terapeuttisesti käyttökelpoisten 7-oksabisykloheptyylisubstituoitujen heterosyklisten amidiprostaglandiinijohdannaisten valmistamiseksi

Country Status (18)

Country	Link
EP (1)	EP0374952A3 (fi)
JP (1)	JPH02221278A (fi)
KR (1)	KR900009639A (fi)
CN (1)	CN1031059C (fi)
AU (1)	AU617569B2 (fi)
CA (1)	CA2006355A1 (fi)
DD (1)	DD286359A5 (fi)
DK (1)	DK172411B1 (fi)
FI (1)	FI97230C (fi)
HU (1)	HUT54161A (fi)
IL (1)	IL92837A (fi)
MX (1)	MX18879A (fi)
NO (1)	NO175258C (fi)
NZ (1)	NZ231962A (fi)
PH (1)	PH27413A (fi)
PL (2)	PL164552B1 (fi)
PT (1)	PT92768B (fi)
ZA (1)	ZA899868B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ232897A (en) *	1989-04-03	1992-12-23	Squibb & Sons Inc	Interphenylene 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogues, preparation and pharmaceutical compositions thereof
DE4035851A1 (de) *	1990-11-10	1992-05-14	Bayer Ag	Substituierte aminosaeureamid-derivate deren herstellung und verwendung
US4977174A (en) *	1989-06-12	1990-12-11	E. R. Squibb & Sons, Inc.	7-oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
NZ233600A (en) *	1989-06-12	1992-10-28	Squibb & Sons Inc	7-oxabicyclo(2.2.1)heptane imidazole prostaglandin analogs and pharmaceutical compositions
US5290799A (en) *	1990-09-19	1994-03-01	E. R. Squibb & Sons, Inc.	7-oxabicycloheptyl substituted heterocyclic thioamide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
US5550248A (en) *	1990-11-29	1996-08-27	E.R. Squibb & Sons, Inc.	Substituted stryl heterocyclic amido prostaglandin analogs
DE4102042A1 (de) *	1991-01-24	1992-07-30	Bayer Ag	Substituierte aminosaeureamid-derivate deren herstellung und verwendung als fungizide
US5135939A (en) *	1991-01-28	1992-08-04	E. R. Squibb & Sons, Inc.	Heterocyclic ketone prostaglandin analogs
IE920039A1 (en) *	1991-02-01	1992-08-12	Squibb & Sons Inc	Heterocyclic amido prostaglandin analogs
US5238951A (en) *	1991-02-01	1993-08-24	E. R. Squibb & Sons, Inc.	Heterocyclic amido prostaglandin analogs
US5158967A (en) *	1991-06-12	1992-10-27	E. R. Squibb & Sons, Inc.	7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
US5162352A (en) *	1991-08-22	1992-11-10	E. R. Squibb & Sons, Inc.	7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs
US5280034A (en) *	1991-08-23	1994-01-18	E. R. Squibb & Sons, Inc.	Bis-heterocyclic prostaglandin analogs
CA2081679A1 (en) *	1991-11-27	1993-05-28	Raj N. Misra	Gem-dialkyl-7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
US5399725A (en) *	1993-05-27	1995-03-21	Bristol-Myers Squibb Co.	7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-vasospastic compounds and method for preparing same
US5849766A (en) *	1996-05-31	1998-12-15	Eli Lilly And Company	Carbamoyl substituted heterocycles
US5849922A (en) *	1996-05-31	1998-12-15	Eli Lilly And Company	Preparation of substituted alkenoic acids
US5856584A (en) *	1997-08-06	1999-01-05	The Nutrasweet Company	Preparation of 3,3-dimethylbutyraldehyde by oxidation of 3, 3-dimethylbutanol
US5905175A (en) *	1998-05-20	1999-05-18	The Nutrasweet Company	Synthesis and purification of 3,3-dimethylbutyraldehyde via oxidation of 1-chloro-3,3-dimethylbutane with dimethyl sulfoxide
CN113912619B (zh) *	2021-11-26	2022-12-06	沈阳药科大学	五味子中提取分离的倍半萜化合物及其方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4456617A (en) *	1983-01-12	1984-06-26	E. R. Squibb & Sons, Inc.	7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4663337A (en) *	1986-04-18	1987-05-05	E. R. Squibb & Sons, Inc.	7-oxabicycloheptane substituted amides useful in the treatment of thrombotic disease

1989
- 1989-12-21 IL IL9283789A patent/IL92837A/en unknown
- 1989-12-21 PH PH39757A patent/PH27413A/en unknown
- 1989-12-21 CA CA002006355A patent/CA2006355A1/en not_active Abandoned
- 1989-12-21 NO NO895170A patent/NO175258C/no not_active IP Right Cessation
- 1989-12-21 NZ NZ231962A patent/NZ231962A/en unknown
- 1989-12-21 ZA ZA899868A patent/ZA899868B/xx unknown
- 1989-12-22 DK DK663189A patent/DK172411B1/da not_active IP Right Cessation
- 1989-12-22 EP EP19890123799 patent/EP0374952A3/en not_active Ceased
- 1989-12-22 AU AU47290/89A patent/AU617569B2/en not_active Ceased
- 1989-12-22 MX MX1887989A patent/MX18879A/es unknown
- 1989-12-22 FI FI896249A patent/FI97230C/fi not_active IP Right Cessation
- 1989-12-22 PL PL89282945A patent/PL164552B1/pl unknown
- 1989-12-22 HU HU896777A patent/HUT54161A/hu unknown
- 1989-12-22 PL PL89300381A patent/PL165147B1/pl unknown
- 1989-12-22 KR KR1019890019281A patent/KR900009639A/ko not_active Application Discontinuation
- 1989-12-23 CN CN89105849A patent/CN1031059C/zh not_active Expired - Fee Related
- 1989-12-25 JP JP1338033A patent/JPH02221278A/ja active Pending
- 1989-12-27 DD DD89336462A patent/DD286359A5/de unknown
- 1989-12-29 PT PT92768A patent/PT92768B/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR900009639A (ko)	1990-07-05
MX18879A (es)	1994-01-31
CA2006355A1 (en)	1990-06-23
PL164552B1 (pl)	1994-08-31
AU4729089A (en)	1990-06-28
CN1031059C (zh)	1996-02-21
JPH02221278A (ja)	1990-09-04
PL165147B1 (pl)	1994-11-30
CN1043716A (zh)	1990-07-11
HU8906777D0 (fi)	1990-03-28
FI97230C (fi)	1996-11-11
HUT54161A (en)	1991-01-28
NO175258C (no)	1994-09-21
DK663189A (da)	1990-06-24
FI97230B (fi)	1996-07-31
ZA899868B (en)	1990-09-26
IL92837A (en)	1994-06-24
PT92768B (pt)	1995-12-29
NO175258B (no)	1994-06-13
NO895170L (no)	1990-06-25
DK663189D0 (da)	1989-12-22
EP0374952A2 (en)	1990-06-27
PH27413A (en)	1993-06-21
NO895170D0 (no)	1989-12-21
EP0374952A3 (en)	1991-03-27
AU617569B2 (en)	1991-11-28
NZ231962A (en)	1992-10-28
PT92768A (pt)	1990-06-29
DD286359A5 (de)	1991-01-24
IL92837A0 (en)	1990-09-17
DK172411B1 (da)	1998-05-25

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Legal Events

Date	Code	Title	Description
1996-07-01	BB	Publication of examined application
2004-08-31	MM	Patent lapsed	Owner name: E.R. SQUIBB & SONS, INC.