FI891283A0 - Ifosfamid-mesna-lyofilisat och foerfarande foer dess framstaellning. - Google Patents

Ifosfamid-mesna-lyofilisat och foerfarande foer dess framstaellning.

Info

Publication number
FI891283A0
FI891283A0 FI891283A FI891283A FI891283A0 FI 891283 A0 FI891283 A0 FI 891283A0 FI 891283 A FI891283 A FI 891283A FI 891283 A FI891283 A FI 891283A FI 891283 A0 FI891283 A0 FI 891283A0
Authority
FI
Finland
Prior art keywords
mesna
lyofilisat
ifosfamid
foerfarande foer
foer dess
Prior art date
Application number
FI891283A
Other languages
English (en)
Other versions
FI891283A (fi
FI89456B (fi
FI89456C (fi
Inventor
Dieter Sauerbier
Otto Isaac
Wolfgang Peter Brade
Original Assignee
Asta Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Pharma Ag filed Critical Asta Pharma Ag
Publication of FI891283A0 publication Critical patent/FI891283A0/fi
Publication of FI891283A publication Critical patent/FI891283A/fi
Publication of FI89456B publication Critical patent/FI89456B/fi
Application granted granted Critical
Publication of FI89456C publication Critical patent/FI89456C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Control Of El Displays (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI891283A 1988-03-19 1989-03-17 Foerfarande foer framstaellning av ifosfamid-mesna-lyofilisat FI89456C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3809337 1988-03-19
DE3809337 1988-03-19

Publications (4)

Publication Number Publication Date
FI891283A0 true FI891283A0 (fi) 1989-03-17
FI891283A FI891283A (fi) 1989-09-20
FI89456B FI89456B (fi) 1993-06-30
FI89456C FI89456C (fi) 1993-10-11

Family

ID=6350216

Family Applications (1)

Application Number Title Priority Date Filing Date
FI891283A FI89456C (fi) 1988-03-19 1989-03-17 Foerfarande foer framstaellning av ifosfamid-mesna-lyofilisat

Country Status (11)

Country Link
US (1) US4959215A (fi)
EP (1) EP0334083B1 (fi)
JP (1) JP2865698B2 (fi)
AT (1) ATE65402T1 (fi)
CA (1) CA1326452C (fi)
DE (1) DE58900183D1 (fi)
ES (1) ES2040394T3 (fi)
FI (1) FI89456C (fi)
GR (1) GR3002377T3 (fi)
IE (1) IE60721B1 (fi)
PT (1) PT90030B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4122167A1 (de) * 1990-07-16 1992-01-23 Asta Pharma Ag Tablette und granulat enthaltend als wirkstoff mesna
US5252341A (en) * 1990-07-16 1993-10-12 Degussa Aktiengesellschaft Tablets and granulates containing mesna as active substance
US5227373A (en) * 1991-10-23 1993-07-13 Bristol-Myers Squibb Co. Lyophilized ifosfamide compositions
DE4233842A1 (de) * 1992-10-08 1994-04-14 Asta Medica Ag Mesna Injektionslösungen
WO1995007083A1 (en) * 1993-09-10 1995-03-16 F.H. Faulding & Co. Limited Ifosfamide lyophilisate composition
US5789000A (en) * 1994-11-14 1998-08-04 Bionumerik Pharmaceuticals, Inc. Sterile aqueous parenteral formulations of cis-diammine dichloro platinum
DE19529057B4 (de) * 1995-08-08 2007-12-13 Baxter Healthcare S.A. Ifosfamid-Lyophilisat-Zubereitungen
IT1284973B1 (it) * 1996-10-11 1998-05-28 A R D O Associazione Ricerca E Uso del sodio 2-mercaptoetansolfonato (mesna) in chirurgia
US6613927B1 (en) 2002-02-08 2003-09-02 American Pharmaceutical Partners, Inc. Sterile lyophilized ifosfamide and associated methods
JP2006508917A (ja) * 2002-09-05 2006-03-16 ブハラット セルムズ アンド ヴァクシンズ リミテッド メスナを有する、オキサザホスホリンの液体安定性組成物
CA2507848A1 (en) * 2002-12-02 2004-06-17 Bharat Serums & Vaccines Ltd. Ifosfamide compositions for parenteral administration and a process for their preparation
US20070192947A1 (en) * 2003-07-10 2007-08-23 Cylena Medical Technologies Inc. Protective apparel with improved doffing
SI1667655T1 (sl) * 2003-10-01 2011-10-28 Baxter Int Nova uporaba, farmacevtski pripravki, kot tudi postopek za njihovo proizvodnjo
EP1799266A2 (en) * 2004-09-13 2007-06-27 Bharat Serums & Vaccines Ltd. Stable emulsion compositions for intravenous administration having antimicrobial preservative efficacy
US8436190B2 (en) 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
US20110138888A1 (en) * 2008-07-21 2011-06-16 Amany Elshorbagy Treatment of obesity
AU2010218109B2 (en) * 2009-02-24 2015-04-09 Dekk-Tec, Inc. Complexes of 4-hydroperoxy ifosfamide as anti-tumor agents
PL2994062T3 (pl) * 2013-05-07 2020-05-18 Auxin Surgery Sa Urządzenie do dysekcji wspomaganej chemicznie
ES2750749T3 (es) 2014-01-06 2020-03-27 Auxin Surgery Sa Composiciones de Mesna liofilizadas

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002495B1 (de) * 1977-12-14 1984-02-15 Asta-Werke Aktiengesellschaft Chemische Fabrik Erzeugnisse zur Anwendung in der cytostatischen Therapie
DE3111428A1 (de) * 1981-03-24 1982-10-07 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
ZA851062B (en) * 1984-03-01 1985-11-27 Asta Werke Ag Chem Fab Salts of oxazaphosphorine derivatives and process for their production
US4797388A (en) * 1984-05-21 1989-01-10 Cetus Corporation Pharmaceutical compositions with galactitol as carrier
US4859452A (en) * 1986-01-17 1989-08-22 Board Of Regents, The University Of Texas System Methods for the reduction of difluoromethylornithine associated toxicity
AU605512B2 (en) * 1986-10-07 1991-01-17 Boehringer Mannheim Italia S.P.A. Pharmaceutical compositions having antineoplastic activity
NO873860L (no) * 1986-10-31 1988-05-02 Asta Pharma Ag Ifosfamid-lyofilisat og fremgangsmaate til deres fremstilling.

Also Published As

Publication number Publication date
EP0334083A1 (de) 1989-09-27
JPH024796A (ja) 1990-01-09
DE58900183D1 (de) 1991-08-29
ES2040394T3 (es) 1993-10-16
CA1326452C (en) 1994-01-25
FI891283A (fi) 1989-09-20
FI89456B (fi) 1993-06-30
US4959215A (en) 1990-09-25
EP0334083B1 (de) 1991-07-24
PT90030B (pt) 1994-05-31
ATE65402T1 (de) 1991-08-15
FI89456C (fi) 1993-10-11
GR3002377T3 (en) 1992-12-30
JP2865698B2 (ja) 1999-03-08
PT90030A (pt) 1989-11-10
IE60721B1 (en) 1994-08-10
IE890854L (en) 1989-09-19

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Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: ASTA MEDICA AKTIENGESELLSCHAFT

MA Patent expired