FI885785A - Epipodofyllotoxinglukosid-4'-acylderivat. - Google Patents

Epipodofyllotoxinglukosid-4'-acylderivat. Download PDF

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Publication number
FI885785A
FI885785A FI885785A FI885785A FI885785A FI 885785 A FI885785 A FI 885785A FI 885785 A FI885785 A FI 885785A FI 885785 A FI885785 A FI 885785A FI 885785 A FI885785 A FI 885785A
Authority
FI
Finland
Prior art keywords
epipodofyllotoxinglukosid
acylderivat
Prior art date
Application number
FI885785A
Other languages
English (en)
Finnish (fi)
Other versions
FI885785A0 (fi
Inventor
Mark G Saulnier
Dolatrai M Vyas
David R Langley
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI885785A0 publication Critical patent/FI885785A0/fi
Publication of FI885785A publication Critical patent/FI885785A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI885785A 1987-12-18 1988-12-14 Epipodofyllotoxinglukosid-4'-acylderivat. FI885785A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13512987A 1987-12-18 1987-12-18

Publications (2)

Publication Number Publication Date
FI885785A0 FI885785A0 (fi) 1988-12-14
FI885785A true FI885785A (fi) 1989-06-19

Family

ID=22466687

Family Applications (1)

Application Number Title Priority Date Filing Date
FI885785A FI885785A (fi) 1987-12-18 1988-12-14 Epipodofyllotoxinglukosid-4'-acylderivat.

Country Status (16)

Country Link
EP (1) EP0320988A3 (da)
JP (1) JPH01279896A (da)
KR (1) KR910008799B1 (da)
CN (1) CN1033631A (da)
AU (1) AU616717B2 (da)
CA (1) CA1312074C (da)
DD (2) DD296082A5 (da)
DK (1) DK702688A (da)
FI (1) FI885785A (da)
HU (1) HU202548B (da)
MY (1) MY104067A (da)
NO (1) NO167668C (da)
NZ (1) NZ227286A (da)
PT (1) PT89253B (da)
YU (2) YU179088A (da)
ZA (2) ZA886810B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868291A (en) * 1987-08-20 1989-09-19 Bristol-Myers Company 4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use
US4965348A (en) * 1989-05-19 1990-10-23 Bristol-Myers Company Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
FR2655047A1 (fr) * 1989-11-24 1991-05-31 Pf Medicament Derives d'etoposide, leur preparation et leur application comme intermediaires de synthese.
AU681337B2 (en) * 1991-10-23 1997-08-28 Cancer Research Campaign Technology Limited Bacterial nitroreductase for the reduction of CB 1954 and analogues thereof to a cytotoxic form
DK2327705T3 (da) * 2001-12-03 2015-08-24 Universitätsklinikum Charité Der Humboldt Universität Zu Berlin Podophyllotoksiner som antiproliferative midler
GB0421296D0 (en) * 2004-09-24 2004-10-27 Angiogene Pharm Ltd Bioreductively-activated prodrugs
EP3415151A1 (en) 2008-05-23 2018-12-19 The University of British Columbia Modified drugs for use in liposomal nanoparticles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE546388A (da) *
NL6613143A (da) * 1965-09-21 1967-03-22
DE3374317D1 (en) * 1982-11-26 1987-12-10 Nippon Kayaku Kk Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof
US4609644A (en) * 1984-06-15 1986-09-02 St. Jude Children's Research Hospital Epipodophyllotoxinquinone glucoside derivatives, method of production and use
IL77334A (en) * 1985-12-16 1991-04-15 Univ Bar Ilan Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor

Also Published As

Publication number Publication date
NO167668C (no) 1991-11-27
YU179088A (en) 1990-02-28
DK702688A (da) 1989-06-19
DD283401A5 (de) 1990-10-10
YU228388A (sh) 1993-10-20
KR910008799B1 (ko) 1991-10-21
CN1033631A (zh) 1989-07-05
DD296082A5 (de) 1991-11-21
MY104067A (en) 1993-11-30
JPH01279896A (ja) 1989-11-10
CA1312074C (en) 1992-12-29
KR890009965A (ko) 1989-08-05
NZ227286A (en) 1991-08-27
DK702688D0 (da) 1988-12-16
NO167668B (no) 1991-08-19
HUT48641A (en) 1989-06-28
EP0320988A3 (en) 1990-08-22
AU2706288A (en) 1989-06-29
PT89253A (pt) 1989-12-29
AU616717B2 (en) 1991-11-07
ZA889392B (en) 1989-09-27
EP0320988A2 (en) 1989-06-21
NO885565L (no) 1989-06-19
PT89253B (pt) 1993-07-30
ZA886810B (en) 1989-08-30
NO885565D0 (no) 1988-12-15
HU202548B (en) 1991-03-28
FI885785A0 (fi) 1988-12-14

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: BRISTOL-MYERS SQUIBB COMPANY