FI883669A - 1-/(4-piperidinyl) metyl/ -1,2,3,4-tetrahydro-9h-pyrido/3.4-b/ indolderivat, deras framstaellning och terapeutiska anvaendning. - Google Patents

1-/(4-piperidinyl) metyl/ -1,2,3,4-tetrahydro-9h-pyrido/3.4-b/ indolderivat, deras framstaellning och terapeutiska anvaendning. Download PDF

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Publication number
FI883669A
FI883669A FI883669A FI883669A FI883669A FI 883669 A FI883669 A FI 883669A FI 883669 A FI883669 A FI 883669A FI 883669 A FI883669 A FI 883669A FI 883669 A FI883669 A FI 883669A
Authority
FI
Finland
Prior art keywords
group
denotes
terapeutiska
indolderivat
anvaendning
Prior art date
Application number
FI883669A
Other languages
English (en)
Other versions
FI883669A0 (fi
Inventor
Mireille Sevrin
Pascal George
Jacques Menin
Claude Morel
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of FI883669A0 publication Critical patent/FI883669A0/fi
Publication of FI883669A publication Critical patent/FI883669A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI883669A 1987-08-07 1988-08-05 1-/(4-piperidinyl) metyl/ -1,2,3,4-tetrahydro-9h-pyrido/3.4-b/ indolderivat, deras framstaellning och terapeutiska anvaendning. FI883669A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8711291A FR2619111B1 (fr) 1987-08-07 1987-08-07 Derives de (piperidinyl-4)methyl-2 tetrahydro-1,2,3,4 9h-pyrido (3,4-b) indole, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FI883669A0 FI883669A0 (fi) 1988-08-05
FI883669A true FI883669A (fi) 1989-02-08

Family

ID=9354027

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883669A FI883669A (fi) 1987-08-07 1988-08-05 1-/(4-piperidinyl) metyl/ -1,2,3,4-tetrahydro-9h-pyrido/3.4-b/ indolderivat, deras framstaellning och terapeutiska anvaendning.

Country Status (17)

Country Link
US (1) US4977159A (fi)
EP (1) EP0302788B1 (fi)
JP (1) JPS6466185A (fi)
KR (1) KR890003756A (fi)
AT (1) ATE72436T1 (fi)
AU (1) AU597188B2 (fi)
DE (1) DE3868301D1 (fi)
DK (1) DK437788A (fi)
FI (1) FI883669A (fi)
FR (1) FR2619111B1 (fi)
GR (1) GR3003920T3 (fi)
HU (1) HU198931B (fi)
IL (1) IL87343A0 (fi)
NO (1) NO166129C (fi)
NZ (1) NZ225706A (fi)
PT (1) PT88206B (fi)
ZA (1) ZA885788B (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4978669A (en) * 1989-06-08 1990-12-18 Neurex Corporation Method of suppressing appetite by administration of tetrahydro-beta-carboline derivatives
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
US5102889B1 (en) * 1990-09-27 1993-05-11 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5455254A (en) * 1991-02-15 1995-10-03 Mondadori; Cesare Substituted benzofuranylpiperidine as a nootropic agent
RU2095339C1 (ru) * 1991-10-17 1997-11-10 Циба-Гейги АГ Производные гидрохинона в свободном виде или в виде соли, способы их получения, производные пиперидина и способы их получения
US5693807A (en) * 1992-10-14 1997-12-02 Ciba-Geigy Corporation Substituted hydroquinone derivatives
CN1109880A (zh) * 1994-02-03 1995-10-11 合成实验室公司 3-(2-氨基乙基)-4-[3-(三氟甲基)苯甲酰基]-3，4-二氢-2h-1，4-苯并噁嗪衍生物、制备及其应用
FR2715659B1 (fr) * 1994-02-03 1996-03-22 Synthelabo Dérivés de 3-(2-aminoéthyl)-4-[3-(trifluorométhyl)benzoyl]-3,4-dihydro-2H-1,4-benzoxazine, leur préparation et leur application en thérapeutique.
WO1996012721A1 (en) * 1994-10-20 1996-05-02 American Home Products Corporation Indole derivatives useful as serotonergic agents
US6255302B1 (en) 1998-12-17 2001-07-03 American Home Products Corporation 1,4-piperazine derivatives
CO5180550A1 (es) 1999-04-19 2002-07-30 Smithkline Beecham Corp Inhibidores de fab i
AR024158A1 (es) 1999-06-01 2002-09-04 Smithkline Beecham Corp Compuestos antibacterianos
AR025976A1 (es) * 1999-10-08 2002-12-26 Affinium Pharm Inc Inhibidores de fab i.
US6762201B1 (en) 1999-10-08 2004-07-13 Affinium Pharmaceuticals, Inc. Fab I inhibitors
US6730684B1 (en) 1999-10-08 2004-05-04 Affinium Pharmaceuticals, Inc. Fab I inhibitors
SI1235830T1 (en) 1999-12-10 2004-06-30 Pfizer Products Inc. PYRROLO(2,3-d)PYRIMIDINE COMPOUNDS AS PROTEIN KINASES INHIBITORS
ES2320984T3 (es) * 2001-04-06 2009-06-01 Affinium Pharmaceuticals, Inc. Inhibidores de fab i.
WO2003049736A1 (en) * 2001-12-11 2003-06-19 Sepracor, Inc. 4-substituted piperidines, and methods of use thereof
KR100742012B1 (ko) 2002-11-21 2007-07-23 화이자 프로덕츠 인코포레이티드 3-아미노-피페리딘 유도체 및 그의 제조 방법
WO2004052890A1 (en) 2002-12-06 2004-06-24 Affinium Pharmaceuticals, Inc. Heterocyclic compounds, methods of making them and their use in therapy
ATE409485T1 (de) 2003-03-17 2008-10-15 Affinium Pharm Inc Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend
ATE414082T1 (de) * 2003-04-29 2008-11-15 Oscient Pharmaceuticals Antibiotische tetrahydro-b-carbolinderivative
KR101299399B1 (ko) 2004-06-04 2013-08-22 아피늄 파마슈티컬스, 인크. 치료제, 및 그의 제조 및 사용 방법
CA2658506C (en) 2006-07-20 2016-01-26 Affinium Pharmaceuticals, Inc. Acrylamide derivatives as fab 1 inhibitors
US8263613B2 (en) 2007-02-16 2012-09-11 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab I inhibitors
BR122021020778B1 (pt) 2012-06-19 2022-07-12 Debiopharm International Sa Derivados de pró-fármaco de (e)-n-metil-n-((3-metilbenzofuran-2-il) metil)-3-(7-oxo-5,6,7,8-tetraidro- 1, 8- naftirindin-3-il) acrilamida
LT3419628T (lt) 2016-02-26 2021-01-25 Debiopharm International Sa Medikamentas diabetinėms pėdų infekcijoms gydyti

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4539407A (en) * 1983-12-13 1985-09-03 American Home Products Corporation β-Carboline anticonvulsants
US4663456A (en) * 1985-09-16 1987-05-05 American Home Products Corporation 2-(substituted piperazinylalkyl)β-carbolines useful in treatment of psychological disorders

Also Published As

Publication number Publication date
DK437788D0 (da) 1988-08-05
NO166129C (no) 1991-06-05
KR890003756A (ko) 1989-04-17
ZA885788B (en) 1989-04-26
GR3003920T3 (fi) 1993-03-16
PT88206B (pt) 1995-05-04
NO883487D0 (no) 1988-08-05
FR2619111B1 (fr) 1991-01-11
FI883669A0 (fi) 1988-08-05
AU2044588A (en) 1989-02-09
IL87343A0 (en) 1989-01-31
US4977159A (en) 1990-12-11
NO166129B (no) 1991-02-25
NZ225706A (en) 1990-04-26
AU597188B2 (en) 1990-05-24
JPS6466185A (en) 1989-03-13
HU198931B (en) 1989-12-28
DE3868301D1 (de) 1992-03-19
NO883487L (no) 1989-02-08
DK437788A (da) 1989-02-07
FR2619111A1 (fr) 1989-02-10
PT88206A (pt) 1989-06-30
EP0302788A1 (fr) 1989-02-08
EP0302788B1 (fr) 1992-02-05
ATE72436T1 (de) 1992-02-15
HUT48242A (en) 1989-05-29

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Owner name: SYNTHELABO