FI882407A - Fibrinolytiska proteiner. - Google Patents
Fibrinolytiska proteiner. Download PDFInfo
- Publication number
- FI882407A FI882407A FI882407A FI882407A FI882407A FI 882407 A FI882407 A FI 882407A FI 882407 A FI882407 A FI 882407A FI 882407 A FI882407 A FI 882407A FI 882407 A FI882407 A FI 882407A
- Authority
- FI
- Finland
- Prior art keywords
- proteiner
- fibrinolytic
- fibrinolytic proteiner
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5341187A | 1987-05-22 | 1987-05-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI882407A0 FI882407A0 (fi) | 1988-05-20 |
FI882407A true FI882407A (fi) | 1988-11-23 |
Family
ID=21984041
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI882407A FI882407A (fi) | 1987-05-22 | 1988-05-20 | Fibrinolytiska proteiner. |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0292009A1 (fi) |
JP (1) | JPS6463379A (fi) |
KR (1) | KR880013978A (fi) |
AU (1) | AU626147B2 (fi) |
DK (1) | DK275788A (fi) |
FI (1) | FI882407A (fi) |
NO (1) | NO882226L (fi) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5079159A (en) * | 1983-12-27 | 1992-01-07 | Genetics Institute, Inc. | Method for making tissue plasminogen activator |
US5736134A (en) * | 1985-04-22 | 1998-04-07 | Genentech, In.C | Tissue plasminogen activator variants |
US5714372A (en) * | 1985-04-22 | 1998-02-03 | Genentech, Inc. | Tissue plasminogen activator variants |
US5756093A (en) * | 1985-04-22 | 1998-05-26 | Genentech, Inc. | Tissue plasminogen activator variants |
US5108901A (en) * | 1988-09-02 | 1992-04-28 | Genentech, Inc. | Tissue plasminogen activator having zymogenic or fibrin specific properties |
US5258180A (en) * | 1988-09-02 | 1993-11-02 | Genetech, Inc. | Tissue plasminogen activator having fibrin specific properties and deletion of amino acids 466-970, compositions and methods of treatment |
US5714145A (en) * | 1988-09-02 | 1998-02-03 | Genentech, Inc. | Tissue plasminogen activator having zymogenic or fibrin specific properties |
US5262170A (en) * | 1988-09-02 | 1993-11-16 | Genentech, Inc. | Tissue plasminogen activator having zymogenic or fibrin specific properties and substituted at amino acid positions 296-299, DNA molecules encoding them, vectors, and host cells |
CA2047702C (en) * | 1989-03-06 | 2000-10-24 | Joseph F. Sambrook | Serpin resistant chymotrypsin superfamily proteases particularly pai-1 resistant t-pa, complementary inhibitor mutants; compositions; genes; expression |
US5550042A (en) * | 1989-03-06 | 1996-08-27 | The Board Of Regents Of The University Of Texas System | Serine protease mutants of the chymotrypsin superfamily resistant to inhibition by their cognate inhibitors and genes encoding the same and serine protease inhibitor mutants and genes encoding the same |
US5866413A (en) * | 1989-03-06 | 1999-02-02 | Board Of Regents Of The University Of Texas System | Pai-1 mutants |
US5190756A (en) * | 1989-12-01 | 1993-03-02 | Genentech, Inc. | Methods and materials for expression of human plasminogen variant |
US5087572A (en) * | 1989-12-01 | 1992-02-11 | Genentech, Inc. | Dna encoding human plasminogen modified at the cleavage site |
GB8927722D0 (en) * | 1989-12-07 | 1990-02-07 | British Bio Technology | Proteins and nucleic acids |
US5242688A (en) * | 1990-12-24 | 1993-09-07 | Eli Lilly And Company | Method of treating thromboembolic disorders by administration of diglycosylated t-pa variants |
EP0618973B1 (en) * | 1991-12-16 | 1996-11-27 | Genentech, Inc. | t-PA SUBSTITUTION VARIANTS WITH IMPROVED FIBRIN-SPECIFICITY |
JP3112480B2 (ja) * | 1991-12-16 | 2000-11-27 | ジェネンテク,インコーポレイテッド | 新規な組織プラスミノーゲン活性化因子変異体 |
AU664469B2 (en) * | 1992-06-03 | 1995-11-16 | Genentech Inc. | Tissue plasminogen activator glycosylation variants with improved therapeutic properties |
DE69738521T2 (de) | 1996-04-05 | 2009-05-07 | Novartis Vaccines and Diagnostics, Inc., Emeryville | Alphaviren-vektors mit einer reduzierten inhibierung der synthese von zellmakromolekülen |
US6706504B1 (en) | 1996-11-12 | 2004-03-16 | The Scripps Research Institute | Tissue type plasminogen activator (t-PA) variants: compositions and methods of use |
JP2007502132A (ja) * | 2003-06-11 | 2007-02-08 | シエーリング アクチエンゲゼルシャフト | 置換活性化配列を有する新規の修飾されたコリン分子及びその使用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984001786A1 (en) * | 1982-10-28 | 1984-05-10 | Beecham Group Plc | Enzyme derivatives and their use in the treatment of thrombosis |
US4753879A (en) * | 1984-08-27 | 1988-06-28 | Biogen N.V. | Modified tissue plasminogen activators |
FI89723C (fi) * | 1984-10-01 | 1993-11-10 | Genzyme Corp | Foerfarande foer framstaellning av vaevnadsplasminogenaktivator, kodande rekombinant-dna daerav och en transformanscell |
DE3682104D1 (de) * | 1985-04-22 | 1991-11-28 | Genentech Inc | Plasminogenaktivator-mutante des menschlichen gewebes, verfahren und zwischenprodukte dafuer und diese mutante verwendende zusammensetzungen. |
GB8513358D0 (en) * | 1985-05-28 | 1985-07-03 | Wellcome Found | Formulation |
US4916071A (en) * | 1985-08-14 | 1990-04-10 | American Home Products Corporation | Poly-kringle plasminogen activator |
EP0227462B1 (en) * | 1985-12-23 | 1992-04-01 | Chiron Corporation | Novel peptide plasminogen activators |
DK43387A (da) * | 1986-01-29 | 1987-07-30 | Beecham Group Plc | Fibrinolytisk enzym |
DE3789664T3 (de) * | 1986-01-31 | 2004-09-16 | Genetics Institute, LLC, Cambridge | Neue thrombolytische proteine. |
GB8608020D0 (en) * | 1986-04-02 | 1986-05-08 | Beecham Group Plc | Compounds |
-
1988
- 1988-05-20 NO NO882226A patent/NO882226L/no unknown
- 1988-05-20 FI FI882407A patent/FI882407A/fi not_active Application Discontinuation
- 1988-05-20 DK DK275788A patent/DK275788A/da not_active Application Discontinuation
- 1988-05-20 EP EP88108148A patent/EP0292009A1/en not_active Withdrawn
- 1988-05-23 JP JP63125612A patent/JPS6463379A/ja active Pending
- 1988-05-23 AU AU16528/88A patent/AU626147B2/en not_active Expired
- 1988-05-24 KR KR1019880006071A patent/KR880013978A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO882226L (no) | 1988-11-23 |
KR880013978A (ko) | 1988-12-22 |
AU626147B2 (en) | 1992-07-23 |
NO882226D0 (no) | 1988-05-20 |
DK275788D0 (da) | 1988-05-20 |
EP0292009A1 (en) | 1988-11-23 |
AU1652888A (en) | 1988-11-24 |
JPS6463379A (en) | 1989-03-09 |
DK275788A (da) | 1989-02-03 |
FI882407A0 (fi) | 1988-05-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed | ||
FD | Application lapsed |
Owner name: ZYMOGENETICS, INC. |