FI873631A0 - --alkyl-4-amino-3-kinolinmetanoler och 1-(4-aralkylamino-3-kinolinyl)alkanoler, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. - Google Patents

--alkyl-4-amino-3-kinolinmetanoler och 1-(4-aralkylamino-3-kinolinyl)alkanoler, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.

Info

Publication number
FI873631A0
FI873631A0 FI873631A FI873631A FI873631A0 FI 873631 A0 FI873631 A0 FI 873631A0 FI 873631 A FI873631 A FI 873631A FI 873631 A FI873631 A FI 873631A FI 873631 A0 FI873631 A0 FI 873631A0
Authority
FI
Finland
Prior art keywords
och
deras
quinolinmethanoler
alkanoler
aralkylamino
Prior art date
Application number
FI873631A
Other languages
English (en)
Other versions
FI86299C (fi
FI873631A (fi
FI86299B (fi
Inventor
Richard Charles Effland
Joseph Thomas Klein
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of FI873631A0 publication Critical patent/FI873631A0/fi
Publication of FI873631A publication Critical patent/FI873631A/fi
Application granted granted Critical
Publication of FI86299B publication Critical patent/FI86299B/fi
Publication of FI86299C publication Critical patent/FI86299C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
FI873631A 1986-08-25 1987-08-21 Foerfarande foer framstaellning av terapeutiskt anvaendbara -alkyl-4-amino-3-kinolinmetanoler. FI86299C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89958486 1986-08-25
US06/899,584 US4789678A (en) 1986-08-25 1986-08-25 Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds

Publications (4)

Publication Number Publication Date
FI873631A0 true FI873631A0 (fi) 1987-08-21
FI873631A FI873631A (fi) 1988-02-26
FI86299B FI86299B (fi) 1992-04-30
FI86299C FI86299C (fi) 1992-08-10

Family

ID=25411249

Family Applications (1)

Application Number Title Priority Date Filing Date
FI873631A FI86299C (fi) 1986-08-25 1987-08-21 Foerfarande foer framstaellning av terapeutiskt anvaendbara -alkyl-4-amino-3-kinolinmetanoler.

Country Status (19)

Country Link
US (1) US4789678A (fi)
EP (1) EP0258755B1 (fi)
JP (1) JPS6360968A (fi)
KR (1) KR880002834A (fi)
AT (2) ATE67189T1 (fi)
AU (1) AU589029B2 (fi)
CA (1) CA1297111C (fi)
DE (1) DE3772905D1 (fi)
DK (1) DK441187A (fi)
ES (1) ES2029812T3 (fi)
FI (1) FI86299C (fi)
GR (1) GR3003299T3 (fi)
HU (1) HU199425B (fi)
IL (1) IL83629A (fi)
NO (1) NO873568L (fi)
NZ (1) NZ221543A (fi)
PH (1) PH25571A (fi)
PT (1) PT85583B (fi)
ZA (1) ZA876254B (fi)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2581382B1 (fr) * 1985-05-06 1987-06-26 Sanofi Sa Derives n-(quinolyl) glycinamides, leur procede de preparation et leur application therapeutique en tant que psychotropes
GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
US4942168A (en) * 1987-07-13 1990-07-17 Hoechst-Roussel Pharmaceuticals Inc. Hydroxyquinoline amines, and method of enhancing memory in mammals
US4743601A (en) * 1987-07-13 1988-05-10 Hoechst-Roussel Pharmaceuticals Inc. Dihydro-1,4-oxazino(2,3-C)quinolines
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
EP0361489A3 (en) * 1988-09-30 1991-06-12 Chugai Seiyaku Kabushiki Kaisha Novel 3,4-diaminoquinoline and pyridine compounds
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
US5110815A (en) * 1990-12-03 1992-05-05 Hoechst-Roussel Pharmaceuticals Inc. 5-amino-5,6,7,8-tetrahydroquinolines and related compounds and pharmaceutical use
GB9122051D0 (en) * 1991-10-17 1991-11-27 Univ Nottingham Medicines
US5493027A (en) * 1993-01-22 1996-02-20 Board Of Regents, The University Of Texas System Anticonvulsive agents and uses thereof
HUP0203045A3 (en) * 1999-09-22 2004-06-28 Sanofi Aventis Deutschland 4-benzylaminoquinoline conjugates with bile acid and their heteroanalogues, methods for producing the same, medicaments containing these compounds and their use
EP2178842A2 (en) 2007-08-22 2010-04-28 Abbott GmbH & Co. KG 4-benzylaminoquinolines, pharmaceutical compositions containing them and their use
MX2010010773A (es) 2008-04-01 2011-04-11 Abbott Gmbh & Co Kg Tetrahidroisoquinolinas, composiciones farmaceuticas que las contienen y su uso en terapia.
AR075442A1 (es) 2009-02-16 2011-03-30 Abbott Gmbh & Co Kg Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia
US9045459B2 (en) 2010-08-13 2015-06-02 AbbVie Deutschland GmbH & Co. KG Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9051280B2 (en) 2010-08-13 2015-06-09 AbbVie Deutschland GmbH & Co. KG Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8846743B2 (en) 2010-08-13 2014-09-30 Abbott Laboratories Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8883839B2 (en) 2010-08-13 2014-11-11 Abbott Laboratories Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8877794B2 (en) 2010-08-13 2014-11-04 Abbott Laboratories Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9309200B2 (en) 2011-05-12 2016-04-12 AbbVie Deutschland GmbH & Co. KG Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy
MX2014001457A (es) 2011-08-05 2014-08-21 Abbvie Deutschland Derivados de aminocromano, de aminotiocromano y de amino-1,2,3,4-tetrahidroquinolina composiciones farmaceuticas que los contienen, y su uso en terapia.
JP2014533675A (ja) 2011-11-18 2014-12-15 アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー Ｎ置換アミノベンゾシクロヘプテン、アミノテトラリン、アミノインダンおよびフェナルキルアミン誘導体、これらを含有する医薬組成物、および治療におけるこれらの使用
US9365512B2 (en) 2012-02-13 2016-06-14 AbbVie Deutschland GmbH & Co. KG Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy
US9656955B2 (en) 2013-03-15 2017-05-23 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9650334B2 (en) 2013-03-15 2017-05-16 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
MX2016004934A (es) 2013-10-17 2016-12-20 Abbvie Deutschland Derivados de aminotetralina y aminoindano, composiciones farmaceuticas que los contienen, y su uso en terapia.
CN105992764A (zh) 2013-10-17 2016-10-05 艾伯维德国有限责任两合公司 氨基色满、氨基硫代色满及氨基-1,2,3,4-四氢喹啉衍生物，包含其的药物组合物及其在治疗中的用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2785165A (en) * 1953-12-22 1957-03-12 Abbott Lab Preparation of 4-aminoquinoline
US3391146A (en) * 1964-11-10 1968-07-02 Bristol Myers Co Nu-substituted carbamates and thiocarbamates of 2-quinolinemethanols
US4180670A (en) * 1977-02-02 1979-12-25 John Wyeth & Brother Limited Amino pyridine derivatives
FR2498187A1 (fr) * 1981-01-16 1982-07-23 Rhone Poulenc Sante Procede de preparation d'amino-4 chloro-7 quinoleines
DE3582995D1 (de) * 1984-10-25 1991-07-04 Hoechst Roussel Pharma 9-amino-1,2,3,4-tetrahydroacridin-1-ol und verwandte verbindungen, verfahren zu ihrer herstellung und verwendung als arzneimittel.
US4631286A (en) * 1984-10-25 1986-12-23 Hoechst-Roussel Pharmaceuticals Inc. 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
US4695573A (en) * 1984-10-25 1987-09-22 Hoechst-Roussel Pharmaceuticals Inc. 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
US4816456A (en) * 1986-10-01 1989-03-28 Summers William K Administration of monoamine acridines in cholinergic neuronal deficit states

Also Published As

Publication number Publication date
DK441187A (da) 1988-02-26
NO873568D0 (no) 1987-08-24
ES2029812T3 (es) 1992-10-01
DE3772905D1 (de) 1991-10-17
ATA260187A (de) 1989-01-15
NO873568L (no) 1988-02-26
ATE67189T1 (de) 1991-09-15
KR880002834A (ko) 1988-05-11
HU199425B (en) 1990-02-28
CA1297111C (en) 1992-03-10
PH25571A (en) 1991-08-08
NZ221543A (en) 1990-09-26
FI86299C (fi) 1992-08-10
US4789678A (en) 1988-12-06
IL83629A (en) 1992-02-16
PT85583A (en) 1987-09-01
IL83629A0 (en) 1988-01-31
PT85583B (pt) 1990-05-31
JPS6360968A (ja) 1988-03-17
AT388729B (de) 1989-08-25
HUT45503A (en) 1988-07-28
ZA876254B (en) 1988-04-27
DK441187D0 (da) 1987-08-24
FI873631A (fi) 1988-02-26
GR3003299T3 (en) 1993-02-17
AU7734387A (en) 1988-02-25
FI86299B (fi) 1992-04-30
EP0258755A1 (en) 1988-03-09
AU589029B2 (en) 1989-09-28
EP0258755B1 (en) 1991-09-11

Similar Documents

Publication Publication Date Title
FI873631A (fi) --alkyl-4-amino-3-kinolinmetanoler och 1-(4-aralkylamino-3-kinolinyl)alkanoler, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
FI904327A0 (fi) N-substituerad-4-pyrimidinaminer och -pyrimidindiaminer, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
FI875145A0 (fi) Kondenserade heterocykliska tetrahydroaminokinoliner och beslaektade foereningar, en metod foer deras framstaellning och deras anvaendning som mediciner.
FI895288A0 (fi) 1,2,3,4-tetrahydro-1,9-akridinaminer, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
FI896243A0 (fi) N-pyridinyl-9h-karbazol-9-aminer, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
NO902813L (no) (1,2,3,4-tetrahydro-9-acridinimino)cykloheksankarboksylsyre og relaterte forbindelser, fremgangsmaate for fremstilling og anvendelse som medikamenter.
FI902851A0 (fi) 4,5,5a,6-tetrahydro-3h-isoxazolo/5,4,3 -kl/akridinderivat, foerfarande foer deras framstaellande och deras anvaendning som laekemedel.
DK571989D0 (da) Hydroxy-1,2,3,4-tetrahydroaminoacridiner, deres fremstilling og anvendelse
DK592589A (da) Kondenserede heterocycliske derivater af 1,2,3,4-tetrahydroacridin, deres fremstilling og anvendelse
ATE130002T1 (de) 1-(pyridinylalkyl)-1h-indole, -indoline und analoge.

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED