FI871828A0 - Substituerade benzamidderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska blandningar. - Google Patents

Substituerade benzamidderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska blandningar.

Info

Publication number
FI871828A0
FI871828A0 FI871828A FI871828A FI871828A0 FI 871828 A0 FI871828 A0 FI 871828A0 FI 871828 A FI871828 A FI 871828A FI 871828 A FI871828 A FI 871828A FI 871828 A0 FI871828 A0 FI 871828A0
Authority
FI
Finland
Prior art keywords
farmaceutiska
benzamidderivat
blandningar
substituerade
foerfarande foer
Prior art date
Application number
FI871828A
Other languages
English (en)
Other versions
FI87776C (fi
FI87776B (fi
FI871828A (fi
Inventor
Tatsuya Kon
Shiro Kato
Toshiya Morie
Kazunori Ohno
Katsuhiko Hino
Tadahiko Karasawa
Naoyuki Yoshida
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of FI871828A0 publication Critical patent/FI871828A0/fi
Publication of FI871828A publication Critical patent/FI871828A/fi
Application granted granted Critical
Publication of FI87776B publication Critical patent/FI87776B/fi
Publication of FI87776C publication Critical patent/FI87776C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/10—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI871828A 1986-04-30 1987-04-27 Foerfarande foer framstaellning av terapeutiskt aktiva substituerade benzamider FI87776C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP10155286 1986-04-30
JP10155286 1986-04-30
JP31509086 1986-12-31
JP31509086 1986-12-31

Publications (4)

Publication Number Publication Date
FI871828A0 true FI871828A0 (fi) 1987-04-27
FI871828A FI871828A (fi) 1987-10-31
FI87776B FI87776B (fi) 1992-11-13
FI87776C FI87776C (fi) 1993-02-25

Family

ID=26442419

Family Applications (1)

Application Number Title Priority Date Filing Date
FI871828A FI87776C (fi) 1986-04-30 1987-04-27 Foerfarande foer framstaellning av terapeutiskt aktiva substituerade benzamider

Country Status (18)

Country Link
US (1) US4870074A (fi)
EP (1) EP0243959B1 (fi)
KR (1) KR870010030A (fi)
AR (1) AR242953A1 (fi)
AU (1) AU592177B2 (fi)
CA (1) CA1291135C (fi)
CZ (1) CZ284687B6 (fi)
DE (1) DE3781195T2 (fi)
DK (1) DK175281B1 (fi)
ES (1) ES2043617T3 (fi)
FI (1) FI87776C (fi)
GR (1) GR3005934T3 (fi)
HK (1) HK18194A (fi)
HU (1) HU198193B (fi)
NZ (1) NZ220120A (fi)
PH (1) PH24049A (fi)
SK (1) SK289787A3 (fi)
SU (1) SU1597101A3 (fi)

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FR2640139A1 (fr) * 1988-12-14 1990-06-15 Delagrange Laboratoires Application de benzamides substitues comme gastromoteurs
TW213460B (fi) * 1991-02-15 1993-09-21 Hokuriku Pharmaceutical
US5395832A (en) * 1991-02-15 1995-03-07 Hokuriku Seiyaku Co., Ltd. Benzamide derivatives
CA2186623A1 (en) * 1994-03-30 1995-10-21 Takeshi Kawakita Benzoic acid compound and use thereof as medicine
US5864039A (en) * 1994-03-30 1999-01-26 Yoshitomi Pharmaceutical Industries, Ltd. Benzoic acid compounds and use thereof as medicaments
EP0827500B1 (en) * 1995-05-23 2001-11-14 Janssen Pharmaceutica N.V. (2-morpholinylmethyl)benzamide derivatives
KR20030031198A (ko) 2000-09-29 2003-04-18 글락소 그룹 리미티드 염증 질환 치료용 모르폴린-아세트아미드 유도체
WO2002044172A1 (en) * 2000-11-28 2002-06-06 Smithkline Beecham P.L.C. Morpholine derivatives as antagonists of orexin receptors
JP4829417B2 (ja) * 2001-03-26 2011-12-07 明夫 乾 インスリン抵抗性改善薬
MXPA04003002A (es) * 2001-10-08 2004-07-15 Sun Pharmaceutical Ind Ltd Un sistema de administracion espacial de farmacos para agentes antiespasmodicos.
GB0207447D0 (en) * 2002-03-28 2002-05-08 Glaxo Group Ltd Novel compounds
GB0208158D0 (en) * 2002-03-28 2002-05-22 Glaxo Group Ltd Novel compounds
GB0207449D0 (en) * 2002-03-28 2002-05-08 Glaxo Group Ltd Novel compounds
HUP0201980A3 (en) * 2002-06-13 2008-06-30 Richter Gedeon Nyrt Process for preparing a benzamide derivative and intermediates thereof
US8153161B2 (en) * 2003-12-09 2012-04-10 Dainippon Sumitomo Pharma Co., Ltd. Medicament-containing particle and a solid preparation containing the particle
US8138204B2 (en) * 2004-01-07 2012-03-20 Aryx Therapeutics, Inc. Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
US8524736B2 (en) 2004-01-07 2013-09-03 Armetheon, Inc. Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
PT1704146E (pt) 2004-01-07 2010-06-30 Aryx Therapeutics Inc Compostos estereoisoméricos e processos para o tratamento de distúrbios gastrointestinais e do sistema nervoso central
DK1801108T3 (da) 2004-09-08 2013-02-18 Mitsubishi Tanabe Pharma Corp Morpholinforbindelser til behandling af inflammationer.
EP1904481B1 (en) 2005-06-23 2016-02-17 Array Biopharma, Inc. Process for preparing benzimidazole compounds
AU2006284601B2 (en) * 2005-08-31 2012-12-20 Renexxion, Llc Synthetic methods and intermediates for stereoisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders
AU2006331731A1 (en) * 2005-12-20 2007-07-05 Merck Sharp & Dohme Corp. Niacin receptor agonists, compositions containing such compounds and methods of treatment
KR100750593B1 (ko) * 2006-03-16 2007-08-20 동우신테크 주식회사 치환된 벤즈아미드 유도체의 제조방법
WO2007149929A1 (en) * 2006-06-23 2007-12-27 Aryx Therapeutics, Inc. Piperidine derivatives for the treatment of gastrointestinal and cns disorders
KR20100105802A (ko) * 2007-04-19 2010-09-29 콘서트 파마슈티컬즈, 인크. 중수소화된 모르폴리닐 화합물
CN101402633A (zh) * 2007-09-11 2009-04-08 上海恒瑞医药有限公司 苯甲酰胺类衍生物、其制备方法及其在医药上的用途
EP2251005B1 (en) 2008-02-13 2012-10-10 Dainippon Sumitomo Pharma Co., Ltd. Orally disintegrating tablets
TWI423967B (zh) * 2008-02-21 2014-01-21 Dainippon Sumitomo Pharma Co 醯胺衍生物及含有其之醫藥組合物
CN101565381B (zh) * 2009-06-01 2013-07-24 重庆英斯凯化工有限公司 2-烷氧基-4-氨基-5-氯苯甲酸的制备方法
WO2011019043A1 (ja) 2009-08-11 2011-02-17 大日本住友製薬株式会社 ２種以上の粒子を含有する口腔内速崩壊錠
WO2011107903A1 (en) 2010-03-04 2011-09-09 Ranbaxy Laboratories Limited Highly pure mosapride citrate dihydrate and processes for its preparation
JP5980236B2 (ja) 2011-02-25 2016-08-31 ユーハン・コーポレイションＹＵＨＡＮ Ｃｏｒｐｏｒａｔｉｏｎ ジアミノピリミジン誘導体及びその製造方法
KR101657616B1 (ko) 2013-05-24 2016-09-19 주식회사유한양행 피리미딘 고리를 포함하는 바이사이클릭 유도체 및 그의 제조방법
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
CN111349052B (zh) * 2020-04-07 2021-02-12 福建海西新药创制有限公司 一种枸橼酸莫沙必利的合成方法
CN114560822B (zh) * 2020-11-27 2024-05-28 鲁南制药集团股份有限公司 一种莫沙必利的二羧酸晶体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH451142A (de) * 1965-01-19 1968-05-15 Sandoz Ag Verfahren zur Herstellung neuer basisch substituierter Benzoesäureamide
US4029786A (en) * 1972-08-11 1977-06-14 Imperial Chemical Industries Limited Morpholine derivatives for treating depression
US4323503A (en) * 1976-08-04 1982-04-06 Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France Substituted 2,3-alkylene di (oxy) benzamides and derivatives
US4210754A (en) * 1977-02-01 1980-07-01 Hoffmann-La Roche Inc. Morpholino containing benzamides
US4692445A (en) * 1983-04-29 1987-09-08 Rorer Pharmaceutical Corporation Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use
FR2575158B1 (fr) * 1984-12-20 1987-10-02 Pf Medicament Arylalcoyloxymethyl-2 morpholines, leur preparation et leur application en tant que medicaments utiles dans le traitement des troubles du systeme nerveux central
JPH0390274A (ja) * 1989-08-28 1991-04-16 Furukawa Alum Co Ltd Ａｌ又はＡｌ合金の気相ろう付法

Also Published As

Publication number Publication date
AR242953A1 (es) 1993-06-30
AU592177B2 (en) 1990-01-04
NZ220120A (en) 1989-06-28
HUT45514A (en) 1988-07-28
FI87776C (fi) 1993-02-25
FI87776B (fi) 1992-11-13
ES2043617T3 (es) 1994-01-01
DK218787A (da) 1987-10-31
CZ289787A3 (cs) 1998-11-11
SK279058B6 (sk) 1998-06-03
US4870074A (en) 1989-09-26
PH24049A (en) 1990-03-05
KR870010030A (ko) 1987-11-30
EP0243959B1 (en) 1992-08-19
GR3005934T3 (fi) 1993-06-07
HU198193B (en) 1989-08-28
HK18194A (en) 1994-03-11
DE3781195D1 (de) 1992-09-24
DE3781195T2 (de) 1993-02-18
DK218787D0 (da) 1987-04-29
CA1291135C (en) 1991-10-22
EP0243959A1 (en) 1987-11-04
FI871828A (fi) 1987-10-31
DK175281B1 (da) 2004-08-09
CZ284687B6 (cs) 1999-02-17
SU1597101A3 (ru) 1990-09-30
AU7227587A (en) 1987-11-05
SK289787A3 (en) 1998-06-03

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: DAINIPPON PHARMACEUTICAL CO., LTD.

MA Patent expired