FI821739A0 - 1-(3-halogen-2-pyridinyl)piperazin - Google Patents

1-(3-halogen-2-pyridinyl)piperazin

Info

Publication number
FI821739A0
FI821739A0 FI821739A FI821739A FI821739A0 FI 821739 A0 FI821739 A0 FI 821739A0 FI 821739 A FI821739 A FI 821739A FI 821739 A FI821739 A FI 821739A FI 821739 A0 FI821739 A0 FI 821739A0
Authority
FI
Finland
Prior art keywords
pyridinyl
piperazine
halogen
halo
treating
Prior art date
Application number
FI821739A
Other languages
English (en)
Inventor
Walfred S Saari
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of FI821739A0 publication Critical patent/FI821739A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI821739A 1981-05-26 1982-05-17 1-(3-halogen-2-pyridinyl)piperazin FI821739A0 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26712081A 1981-05-26 1981-05-26

Publications (1)

Publication Number Publication Date
FI821739A0 true FI821739A0 (fi) 1982-05-17

Family

ID=23017399

Family Applications (1)

Application Number Title Priority Date Filing Date
FI821739A FI821739A0 (fi) 1981-05-26 1982-05-17 1-(3-halogen-2-pyridinyl)piperazin

Country Status (17)

Country Link
EP (1) EP0065757B1 (fi)
JP (1) JPS6055068B2 (fi)
AT (1) ATE11134T1 (fi)
AU (1) AU547319B2 (fi)
CA (1) CA1214467A (fi)
DE (1) DE3261827D1 (fi)
DK (1) DK234282A (fi)
ES (4) ES8306740A1 (fi)
FI (1) FI821739A0 (fi)
GR (1) GR76413B (fi)
IE (1) IE53035B1 (fi)
IL (1) IL65802A (fi)
NO (1) NO821730L (fi)
NZ (1) NZ200642A (fi)
PH (1) PH18686A (fi)
PT (1) PT74926B (fi)
ZA (1) ZA823611B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH056685U (ja) * 1991-07-09 1993-01-29 株式会社ユアサコーポレーシヨン 電池の艤装構造
US7345096B2 (en) 2002-10-15 2008-03-18 Wyeth Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms
US20040152710A1 (en) * 2002-10-15 2004-08-05 Deecher Darlene Coleman Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms
US7419980B2 (en) 2003-10-14 2008-09-02 Wyeth Fused-aryl and heteroaryl derivatives and methods of their use
US7365076B2 (en) 2003-10-14 2008-04-29 Wyeth Substituted aryl cycloalkanol derivatives and methods of their use
US7524846B2 (en) 2003-10-14 2009-04-28 Wyeth Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use
US7402698B2 (en) 2003-10-14 2008-07-22 Wyeth Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use
US7550485B2 (en) 2003-10-14 2009-06-23 Wyeth Substituted N-heterocycle derivatives and methods of their use
US7531543B2 (en) 2003-10-14 2009-05-12 Wyeth Phenylpiperazine cycloalkanol derivatives and methods of their use
US7491723B2 (en) 2003-10-14 2009-02-17 Wyeth Alkanol and cycloalkanol-amine derivatives and methods of their use
US7517899B2 (en) 2004-03-30 2009-04-14 Wyeth Phenylaminopropanol derivatives and methods of their use
US7414052B2 (en) 2004-03-30 2008-08-19 Wyeth Phenylaminopropanol derivatives and methods of their use
CN101671297B (zh) * 2008-09-11 2012-05-09 上海药明康德新药开发有限公司 4-(3-碘-2-吡啶基)哌嗪类化合物的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773951A (en) * 1972-12-21 1973-11-20 Miles Lab Method of treating depression with 1-(2-pyridyl)piperazine
US4078063A (en) * 1976-09-24 1978-03-07 Merck & Co., Inc. Piperazinylpyridines

Also Published As

Publication number Publication date
ES8403476A1 (es) 1984-03-16
JPS584766A (ja) 1983-01-11
AU8380282A (en) 1982-12-02
EP0065757A1 (en) 1982-12-01
ATE11134T1 (de) 1985-01-15
ZA823611B (en) 1983-12-28
ES512533A0 (es) 1983-06-01
GR76413B (fi) 1984-08-10
DE3261827D1 (en) 1985-02-21
IE821225L (en) 1982-11-26
ES519856A0 (es) 1984-03-16
DK234282A (da) 1982-11-27
PT74926A (en) 1982-06-01
PH18686A (en) 1985-08-29
ES519854A0 (es) 1984-03-16
ES8403475A1 (es) 1984-03-16
ES8306740A1 (es) 1983-06-01
EP0065757B1 (en) 1985-01-09
AU547319B2 (en) 1985-10-17
NZ200642A (en) 1984-11-09
ES519855A0 (es) 1984-03-16
CA1214467A (en) 1986-11-25
IL65802A (en) 1985-12-31
ES8403477A1 (es) 1984-03-16
JPS6055068B2 (ja) 1985-12-03
IE53035B1 (en) 1988-05-11
PT74926B (en) 1985-05-16
NO821730L (no) 1982-11-29
IL65802A0 (en) 1982-08-31

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: MERCK & CO INC