FI801600A - Foerfarande foer framstaellning av pyrimidinfoereningar - Google Patents

Foerfarande foer framstaellning av pyrimidinfoereningar

Info

Publication number
FI801600A
FI801600A FI801600A FI801600A FI801600A FI 801600 A FI801600 A FI 801600A FI 801600 A FI801600 A FI 801600A FI 801600 A FI801600 A FI 801600A FI 801600 A FI801600 A FI 801600A
Authority
FI
Finland
Prior art keywords
pyrimides
framework
Prior art date
Application number
FI801600A
Other languages
English (en)
Inventor
Adrian Marxer
Kurt Eichenberger
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI801600A publication Critical patent/FI801600A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI801600A 1979-05-18 1980-05-16 Foerfarande foer framstaellning av pyrimidinfoereningar FI801600A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH466979 1979-05-18

Publications (1)

Publication Number Publication Date
FI801600A true FI801600A (fi) 1980-11-19

Family

ID=4280399

Family Applications (1)

Application Number Title Priority Date Filing Date
FI801600A FI801600A (fi) 1979-05-18 1980-05-16 Foerfarande foer framstaellning av pyrimidinfoereningar

Country Status (21)

Country Link
EP (1) EP0019811A1 (fi)
JP (1) JPS55154971A (fi)
KR (1) KR830002757A (fi)
AR (1) AR228256A1 (fi)
AU (1) AU5848480A (fi)
DD (1) DD150609A5 (fi)
DK (1) DK214480A (fi)
ES (1) ES8104279A1 (fi)
FI (1) FI801600A (fi)
GB (1) GB2052487B (fi)
GR (1) GR68453B (fi)
IE (1) IE49803B1 (fi)
IL (1) IL60086A (fi)
MA (1) MA18829A1 (fi)
NO (1) NO801469L (fi)
NZ (1) NZ193730A (fi)
OA (1) OA06533A (fi)
PL (1) PL224313A1 (fi)
PT (1) PT71251A (fi)
ZA (1) ZA802909B (fi)
ZW (1) ZW11880A1 (fi)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507146A (en) * 1982-12-28 1985-03-26 Ciba-Geigy Corporation 2,4-Diamino-6-halo-5-trifluoromethylpyrimidines having herbicidal activity
DE3829469A1 (de) * 1988-08-31 1990-03-01 Bayer Ag Verfahren zur herstellung von substituierten n-azinyl-n'-sulfonyl-isothioharnstoffen und n-azinyl-iminodithiokohlensaeure-s,s-diester als zwischenprodukte zu ihrer herstellung
CA2269971A1 (en) * 1997-09-03 1999-03-11 Trent Lee Abraham Pyrimidine derivatives
US7473691B2 (en) 2000-09-15 2009-01-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US6660731B2 (en) 2000-09-15 2003-12-09 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
KR100876069B1 (ko) 2000-09-15 2008-12-26 버텍스 파마슈티칼스 인코포레이티드 단백질 키나제 억제제로서 유용한 피라졸 화합물 및 이를 포함하는 약제학적 조성물
MXPA03005610A (es) 2000-12-21 2003-10-06 Vertex Pharma Compuestos de pirazol utiles como inhibidores de la proteina cinasa.
HUP0401858A3 (en) * 2001-01-31 2009-06-29 Lundbeck & Co As H Gal3 receptor antagonist pyrimidine and indolone-derivatives and their use for preparation of pharmaceutical compositions suitable for the treatment of depression and/or anxiety
US7229993B2 (en) 2002-03-13 2007-06-12 Euro-Celtique S.A. Aryl substituted pyrimidines and the use thereof
AU2003214110A1 (en) * 2002-03-15 2003-09-29 Ciba Specialty Chemicals Holding Inc. 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces
US20040009981A1 (en) 2002-03-15 2004-01-15 David Bebbington Compositions useful as inhibitors of protein kinases
MY141867A (en) 2002-06-20 2010-07-16 Vertex Pharma Substituted pyrimidines useful as protein kinase inhibitors
MXPA05001367A (es) 2002-08-02 2005-04-28 Vertex Pharma Composiciones de pirazol utiles como inhibidores de gsk-3.
US7601718B2 (en) 2003-02-06 2009-10-13 Vertex Pharmaceuticals Incorporated Compositions useful as inhibitors of protein kinases
AU2006279376B2 (en) 2005-08-18 2011-04-14 Vertex Pharmaceuticals Incoporated Pyrazine kinase inhibitors
EP1951715B1 (en) 2005-11-03 2013-09-04 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
ATE457311T1 (de) 2006-11-02 2010-02-15 Vertex Pharma Als inhibitoren von proteinkinasen geeignete aminopyridine und aminopyrimidine
DE602007007985D1 (de) 2006-12-19 2010-09-02 Vertex Pharma Als inhibitoren von proteinkinasen geeignete aminopyrimidine
MX2009009591A (es) 2007-03-09 2009-11-10 Vertex Pharma Aminopirimidinas utiles como inhibidores de proteinas cinasas.
CA2679701A1 (en) 2007-03-09 2008-09-18 Vertex Pharmaceuticals Incorporated Aminopyridines useful as inhibitors of protein kinases
ES2435997T3 (es) 2007-03-09 2013-12-26 Vertex Pharmaceuticals, Inc. Aminopirimidinas útiles como inhibidores de las proteínas cinasas
WO2008128009A2 (en) 2007-04-13 2008-10-23 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
WO2008137621A1 (en) 2007-05-02 2008-11-13 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
JP5389785B2 (ja) 2007-05-02 2014-01-15 バーテックス ファーマシューティカルズ インコーポレイテッド キナーゼ阻害剤として有用なチアゾールおよびピラゾール
AU2008282156B2 (en) 2007-07-31 2014-07-17 Vertex Pharmaceuticals Incorporated Process for preparing 5-fluoro-1H-pyrazolo [3, 4-b] pyridin-3-amine and derivatives thereof
RU2011112802A (ru) 2008-09-03 2012-10-10 Вертекс Фармасьютикалз Инкорпорейтед (Us) Сокристаллы и содержащие их фармацевтические композиции
AU2009333559B2 (en) * 2008-12-09 2015-03-12 Gilead Sciences, Inc. Modulators of toll-like receptors
KR102328682B1 (ko) * 2018-08-27 2021-11-18 주식회사 대웅제약 신규한 헤테로사이클릭아민 유도체 및 이를 포함하는 약학 조성물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754832A (fr) * 1969-08-14 1971-02-15 Beecham Group Ltd Iminazolines

Also Published As

Publication number Publication date
MA18829A1 (fr) 1980-12-31
IL60086A (en) 1984-03-30
KR830002757A (ko) 1983-05-30
PT71251A (en) 1980-06-01
ES491514A0 (es) 1981-04-16
AR228256A1 (es) 1983-02-15
PL224313A1 (fi) 1981-02-13
GR68453B (fi) 1981-12-30
IE801023L (en) 1980-11-18
DK214480A (da) 1980-11-19
NZ193730A (en) 1982-12-21
GB2052487B (en) 1983-05-11
ZA802909B (en) 1981-05-27
EP0019811A1 (de) 1980-12-10
JPS55154971A (en) 1980-12-02
OA06533A (fr) 1981-07-31
ZW11880A1 (en) 1980-12-17
GB2052487A (en) 1981-01-28
NO801469L (no) 1980-11-19
DD150609A5 (de) 1981-09-09
IE49803B1 (en) 1985-12-25
AU5848480A (en) 1980-11-20
ES8104279A1 (es) 1981-04-16
IL60086A0 (en) 1980-07-31

Similar Documents

Publication Publication Date Title
FI790321A (fi) Foerfarande foer framstaellning av 6-substituerade tia-azafoereningar
FI801600A (fi) Foerfarande foer framstaellning av pyrimidinfoereningar
FI803508L (fi) Foerfarande foer framstaellning av imidazol-5-aettiksyrederivat
FI800008A (fi) Foerfarande foer framstaellning av peptidylargininaldehyd-derivat
FI802029A (fi) Foerbaettringar i tillverkningen av foedoprodukter
NO151269C (no) Fremgangsmaate for fremstilling av fiskemel
FI813279L (fi) Foerfarande foer framstaellning av azabicyklo-oktan-karbolxylsyror
FI801460A (fi) Foerfarande foer blandning av vaetskor i slutna kaerl
FI793637A (fi) Anordning foer lagring av sjaelvupphettande radioaktiva aemnen
FI792207A (fi) Anordning foer snabb avskiljning av valsarna i en kalander
FI784040A (fi) Foerfarande foer framstaellning av fibervals
FI803547L (fi) Foerfaranden foer framstaellning av nya piperidylbensimidazolinoner
FI64204B (fi) Anordning foer indragning av en varubana i en svaevtork
FI802408A (fi) Foerfarande foer framstaellning av substituerade tetra-azatricyclen
FI65794B (fi) Foerfarande foer framstaellning av bindemedel foer haeftlim
FI791564A (fi) Foerfarande foer rengoering av en torkvira i en pappersmaskin
FI801125A (fi) Anordning foer infoering av en materialbana i en behandlingsanlaeggning
FI793199A (fi) Anordning foer oeppnande av aokdonstak
FI800957A (fi) Extruderingsanordning foer framstaellning av en tillslutningsremsa av plast
FI781357A (fi) Foerfarande och anordning foer framstaellning av polyuretanskum
FI802673A (fi) Foerfarande foer framstaellning av polyazatiafoereningar
FI791753A (fi) Anordning foer styrning av raelsfordon i dragkoppling
FI792220A (fi) Foerfarande foer framstaellning av pyrimidinfoereningar
FI802999A (fi) Foerfarande foer framstaellning av en fluorecerande bildskaerm foer faergbildroer
FI782574A (fi) Foerfarande foer framstaellning av n-substituerade 2-hydrazonopropionsyraderivat

Legal Events

Date Code Title Description
FD Application lapsed

Owner name: CIBA-GEIGY AG