FI801600A - Foerfarande foer framstaellning av pyrimidinfoereningar - Google Patents
Foerfarande foer framstaellning av pyrimidinfoereningarInfo
- Publication number
- FI801600A FI801600A FI801600A FI801600A FI801600A FI 801600 A FI801600 A FI 801600A FI 801600 A FI801600 A FI 801600A FI 801600 A FI801600 A FI 801600A FI 801600 A FI801600 A FI 801600A
- Authority
- FI
- Finland
- Prior art keywords
- pyrimides
- framework
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH466979 | 1979-05-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
FI801600A true FI801600A (fi) | 1980-11-19 |
Family
ID=4280399
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI801600A FI801600A (fi) | 1979-05-18 | 1980-05-16 | Foerfarande foer framstaellning av pyrimidinfoereningar |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0019811A1 (fi) |
JP (1) | JPS55154971A (fi) |
KR (1) | KR830002757A (fi) |
AR (1) | AR228256A1 (fi) |
AU (1) | AU5848480A (fi) |
DD (1) | DD150609A5 (fi) |
DK (1) | DK214480A (fi) |
ES (1) | ES8104279A1 (fi) |
FI (1) | FI801600A (fi) |
GB (1) | GB2052487B (fi) |
GR (1) | GR68453B (fi) |
IE (1) | IE49803B1 (fi) |
IL (1) | IL60086A (fi) |
MA (1) | MA18829A1 (fi) |
NO (1) | NO801469L (fi) |
NZ (1) | NZ193730A (fi) |
OA (1) | OA06533A (fi) |
PL (1) | PL224313A1 (fi) |
PT (1) | PT71251A (fi) |
ZA (1) | ZA802909B (fi) |
ZW (1) | ZW11880A1 (fi) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4507146A (en) * | 1982-12-28 | 1985-03-26 | Ciba-Geigy Corporation | 2,4-Diamino-6-halo-5-trifluoromethylpyrimidines having herbicidal activity |
DE3829469A1 (de) * | 1988-08-31 | 1990-03-01 | Bayer Ag | Verfahren zur herstellung von substituierten n-azinyl-n'-sulfonyl-isothioharnstoffen und n-azinyl-iminodithiokohlensaeure-s,s-diester als zwischenprodukte zu ihrer herstellung |
CA2269971A1 (en) * | 1997-09-03 | 1999-03-11 | Trent Lee Abraham | Pyrimidine derivatives |
US7473691B2 (en) | 2000-09-15 | 2009-01-06 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
US6660731B2 (en) | 2000-09-15 | 2003-12-09 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
KR100876069B1 (ko) | 2000-09-15 | 2008-12-26 | 버텍스 파마슈티칼스 인코포레이티드 | 단백질 키나제 억제제로서 유용한 피라졸 화합물 및 이를 포함하는 약제학적 조성물 |
MXPA03005610A (es) | 2000-12-21 | 2003-10-06 | Vertex Pharma | Compuestos de pirazol utiles como inhibidores de la proteina cinasa. |
HUP0401858A3 (en) * | 2001-01-31 | 2009-06-29 | Lundbeck & Co As H | Gal3 receptor antagonist pyrimidine and indolone-derivatives and their use for preparation of pharmaceutical compositions suitable for the treatment of depression and/or anxiety |
US7229993B2 (en) | 2002-03-13 | 2007-06-12 | Euro-Celtique S.A. | Aryl substituted pyrimidines and the use thereof |
AU2003214110A1 (en) * | 2002-03-15 | 2003-09-29 | Ciba Specialty Chemicals Holding Inc. | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces |
US20040009981A1 (en) | 2002-03-15 | 2004-01-15 | David Bebbington | Compositions useful as inhibitors of protein kinases |
MY141867A (en) | 2002-06-20 | 2010-07-16 | Vertex Pharma | Substituted pyrimidines useful as protein kinase inhibitors |
MXPA05001367A (es) | 2002-08-02 | 2005-04-28 | Vertex Pharma | Composiciones de pirazol utiles como inhibidores de gsk-3. |
US7601718B2 (en) | 2003-02-06 | 2009-10-13 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of protein kinases |
AU2006279376B2 (en) | 2005-08-18 | 2011-04-14 | Vertex Pharmaceuticals Incoporated | Pyrazine kinase inhibitors |
EP1951715B1 (en) | 2005-11-03 | 2013-09-04 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines useful as kinase inhibitors |
ATE457311T1 (de) | 2006-11-02 | 2010-02-15 | Vertex Pharma | Als inhibitoren von proteinkinasen geeignete aminopyridine und aminopyrimidine |
DE602007007985D1 (de) | 2006-12-19 | 2010-09-02 | Vertex Pharma | Als inhibitoren von proteinkinasen geeignete aminopyrimidine |
MX2009009591A (es) | 2007-03-09 | 2009-11-10 | Vertex Pharma | Aminopirimidinas utiles como inhibidores de proteinas cinasas. |
CA2679701A1 (en) | 2007-03-09 | 2008-09-18 | Vertex Pharmaceuticals Incorporated | Aminopyridines useful as inhibitors of protein kinases |
ES2435997T3 (es) | 2007-03-09 | 2013-12-26 | Vertex Pharmaceuticals, Inc. | Aminopirimidinas útiles como inhibidores de las proteínas cinasas |
WO2008128009A2 (en) | 2007-04-13 | 2008-10-23 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines useful as kinase inhibitors |
WO2008137621A1 (en) | 2007-05-02 | 2008-11-13 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines useful as kinase inhibitors |
JP5389785B2 (ja) | 2007-05-02 | 2014-01-15 | バーテックス ファーマシューティカルズ インコーポレイテッド | キナーゼ阻害剤として有用なチアゾールおよびピラゾール |
AU2008282156B2 (en) | 2007-07-31 | 2014-07-17 | Vertex Pharmaceuticals Incorporated | Process for preparing 5-fluoro-1H-pyrazolo [3, 4-b] pyridin-3-amine and derivatives thereof |
RU2011112802A (ru) | 2008-09-03 | 2012-10-10 | Вертекс Фармасьютикалз Инкорпорейтед (Us) | Сокристаллы и содержащие их фармацевтические композиции |
AU2009333559B2 (en) * | 2008-12-09 | 2015-03-12 | Gilead Sciences, Inc. | Modulators of toll-like receptors |
KR102328682B1 (ko) * | 2018-08-27 | 2021-11-18 | 주식회사 대웅제약 | 신규한 헤테로사이클릭아민 유도체 및 이를 포함하는 약학 조성물 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE754832A (fr) * | 1969-08-14 | 1971-02-15 | Beecham Group Ltd | Iminazolines |
-
1980
- 1980-05-05 MA MA19025A patent/MA18829A1/fr unknown
- 1980-05-13 DD DD80221082A patent/DD150609A5/de unknown
- 1980-05-14 ES ES491514A patent/ES8104279A1/es not_active Expired
- 1980-05-15 IL IL60086A patent/IL60086A/xx unknown
- 1980-05-15 NZ NZ193730A patent/NZ193730A/xx unknown
- 1980-05-16 DK DK214480A patent/DK214480A/da not_active Application Discontinuation
- 1980-05-16 ZA ZA00802909A patent/ZA802909B/xx unknown
- 1980-05-16 FI FI801600A patent/FI801600A/fi not_active Application Discontinuation
- 1980-05-16 PT PT71251A patent/PT71251A/pt unknown
- 1980-05-16 AU AU58484/80A patent/AU5848480A/en not_active Abandoned
- 1980-05-16 ZW ZW118/80A patent/ZW11880A1/xx unknown
- 1980-05-16 GR GR61963A patent/GR68453B/el unknown
- 1980-05-16 IE IE1023/80A patent/IE49803B1/en unknown
- 1980-05-16 EP EP80102724A patent/EP0019811A1/de not_active Withdrawn
- 1980-05-16 NO NO801469A patent/NO801469L/no unknown
- 1980-05-16 GB GB8016309A patent/GB2052487B/en not_active Expired
- 1980-05-17 OA OA57113A patent/OA06533A/xx unknown
- 1980-05-17 PL PL22431380A patent/PL224313A1/xx unknown
- 1980-05-17 KR KR1019800001944A patent/KR830002757A/ko unknown
- 1980-05-17 JP JP6586380A patent/JPS55154971A/ja active Pending
- 1980-05-19 AR AR281109A patent/AR228256A1/es active
Also Published As
Publication number | Publication date |
---|---|
MA18829A1 (fr) | 1980-12-31 |
IL60086A (en) | 1984-03-30 |
KR830002757A (ko) | 1983-05-30 |
PT71251A (en) | 1980-06-01 |
ES491514A0 (es) | 1981-04-16 |
AR228256A1 (es) | 1983-02-15 |
PL224313A1 (fi) | 1981-02-13 |
GR68453B (fi) | 1981-12-30 |
IE801023L (en) | 1980-11-18 |
DK214480A (da) | 1980-11-19 |
NZ193730A (en) | 1982-12-21 |
GB2052487B (en) | 1983-05-11 |
ZA802909B (en) | 1981-05-27 |
EP0019811A1 (de) | 1980-12-10 |
JPS55154971A (en) | 1980-12-02 |
OA06533A (fr) | 1981-07-31 |
ZW11880A1 (en) | 1980-12-17 |
GB2052487A (en) | 1981-01-28 |
NO801469L (no) | 1980-11-19 |
DD150609A5 (de) | 1981-09-09 |
IE49803B1 (en) | 1985-12-25 |
AU5848480A (en) | 1980-11-20 |
ES8104279A1 (es) | 1981-04-16 |
IL60086A0 (en) | 1980-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |
Owner name: CIBA-GEIGY AG |