FI66874B - Foerfarande foer framstaellning av kristallina salter av 7beta-(2-(2-amino-4-tiazolyl)-2-metoxi-iminoacetamido)-3-cefem-4-karboxylsyra-pivaloyloximetylester - Google Patents
Foerfarande foer framstaellning av kristallina salter av 7beta-(2-(2-amino-4-tiazolyl)-2-metoxi-iminoacetamido)-3-cefem-4-karboxylsyra-pivaloyloximetylester Download PDFInfo
- Publication number
- FI66874B FI66874B FI810270A FI810270A FI66874B FI 66874 B FI66874 B FI 66874B FI 810270 A FI810270 A FI 810270A FI 810270 A FI810270 A FI 810270A FI 66874 B FI66874 B FI 66874B
- Authority
- FI
- Finland
- Prior art keywords
- amino
- thiazolyl
- crystalline
- ester
- pivaloyloximethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Liquid Crystal Substances (AREA)
- Seasonings (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Sorption Type Refrigeration Machines (AREA)
- Magnetic Heads (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH83680 | 1980-02-01 | ||
CH83680 | 1980-02-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI810270L FI810270L (fi) | 1981-08-02 |
FI66874B true FI66874B (fi) | 1984-08-31 |
Family
ID=4196332
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI810270A FI66874B (fi) | 1980-02-01 | 1981-01-30 | Foerfarande foer framstaellning av kristallina salter av 7beta-(2-(2-amino-4-tiazolyl)-2-metoxi-iminoacetamido)-3-cefem-4-karboxylsyra-pivaloyloximetylester |
Country Status (26)
Country | Link |
---|---|
US (1) | US4411897A (it) |
EP (1) | EP0033518B1 (it) |
JP (1) | JPS56122382A (it) |
KR (1) | KR840000502B1 (it) |
AT (1) | ATE3550T1 (it) |
AU (1) | AU6677981A (it) |
CA (1) | CA1146540A (it) |
CS (1) | CS219851B2 (it) |
DD (1) | DD157462A5 (it) |
DE (1) | DE3160328D1 (it) |
DK (1) | DK32081A (it) |
ES (1) | ES498989A0 (it) |
FI (1) | FI66874B (it) |
GR (1) | GR78221B (it) |
IE (1) | IE50888B1 (it) |
IL (1) | IL62017A (it) |
MC (1) | MC1367A1 (it) |
MT (1) | MTP882B (it) |
NO (1) | NO810338L (it) |
NZ (1) | NZ196159A (it) |
OA (1) | OA06732A (it) |
PL (1) | PL125899B1 (it) |
PT (1) | PT72421A (it) |
SU (1) | SU1036250A1 (it) |
ZA (1) | ZA81631B (it) |
ZW (1) | ZW2281A1 (it) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2111043B (en) * | 1980-12-12 | 1985-02-06 | Ciba Geigy Ag | Novel cephalosporin esters |
US4400503A (en) * | 1981-10-30 | 1983-08-23 | Eli Lilly And Company | Purification of syn-7-[[(2-amino-4-thiazolyl)(methoxyimino) acetyl]amino]-3-methyl-3-cephem-4-carboxylic acid |
US4594417A (en) * | 1981-10-30 | 1986-06-10 | Eli Lilly Company | Crystalline antibiotic salt |
JPS60190783A (ja) * | 1983-12-21 | 1985-09-28 | Sumitomo Seiyaku Kk | セフエム系化合物 |
US4683227A (en) * | 1985-07-09 | 1987-07-28 | Eli Lilly And Company | Antibiotic derivatives of 7β-[2-(thiazol-4-yl)acetamide]-3-chloro-3-cephem-4-carboxylic acids and compositions and method of use thereof |
JPH02101081A (ja) * | 1988-10-08 | 1990-04-12 | Meiji Seika Kaisha Ltd | セファロスポリン誘導体結晶性二塩酸塩及びその製造法 |
EP0638573A1 (en) * | 1993-08-10 | 1995-02-15 | Lucky Ltd. | Crystalline hydrates of cephalosporin and process for preparation thereof |
US20040067192A1 (en) * | 2002-10-07 | 2004-04-08 | The Procter & Gamble Company | Conversion of sodium bromide to anhydrous hydrobromic acid and sodium bisulfate |
MXPA05010083A (es) * | 2003-03-27 | 2005-11-23 | Basilea Pharmaceutica Ag | Cefalosporina en forma cristalina. |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH17188A (en) | 1977-03-14 | 1984-06-14 | Fujisawa Pharmaceutical Co | New cephem and cepham compounds and their pharmaceutical compositions and method of use |
US4370326A (en) * | 1977-09-13 | 1983-01-25 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds and composition |
GB2025933B (en) | 1978-06-13 | 1982-10-27 | Fujisawa Pharmaceutical Co | Cephem and cepham compounds |
MA18686A1 (fr) * | 1978-07-07 | 1980-10-01 | Ciba Geigy Ag | Composes aminothiazoliques |
JPS5543011A (en) * | 1978-09-20 | 1980-03-26 | Shionogi & Co Ltd | 7-halothiazolylalkoxyiminoacetamido-3-cephem compound |
JPS5579393A (en) * | 1978-12-11 | 1980-06-14 | Takeda Chem Ind Ltd | Cephalosporin derivative and its preparation |
JPS55151588A (en) * | 1979-05-14 | 1980-11-26 | Takeda Chem Ind Ltd | Preparation of cephalosporin salt crystal |
-
1979
- 1979-02-15 GR GR64006A patent/GR78221B/el unknown
-
1981
- 1981-01-15 US US06/225,295 patent/US4411897A/en not_active Expired - Fee Related
- 1981-01-15 MT MT882A patent/MTP882B/xx unknown
- 1981-01-21 MC MC811493A patent/MC1367A1/xx unknown
- 1981-01-23 DK DK32081A patent/DK32081A/da not_active Application Discontinuation
- 1981-01-28 OA OA57312A patent/OA06732A/xx unknown
- 1981-01-28 DD DD81227278A patent/DD157462A5/de unknown
- 1981-01-29 AT AT81100643T patent/ATE3550T1/de not_active IP Right Cessation
- 1981-01-29 EP EP81100643A patent/EP0033518B1/de not_active Expired
- 1981-01-29 DE DE8181100643T patent/DE3160328D1/de not_active Expired
- 1981-01-29 PT PT72421A patent/PT72421A/pt unknown
- 1981-01-30 SU SU3238101A patent/SU1036250A1/ru active
- 1981-01-30 PL PL1981229457A patent/PL125899B1/pl unknown
- 1981-01-30 FI FI810270A patent/FI66874B/fi not_active Application Discontinuation
- 1981-01-30 CS CS81685A patent/CS219851B2/cs unknown
- 1981-01-30 IL IL62017A patent/IL62017A/xx unknown
- 1981-01-30 NZ NZ196159A patent/NZ196159A/xx unknown
- 1981-01-30 AU AU66779/81A patent/AU6677981A/en not_active Abandoned
- 1981-01-30 ZA ZA00810631A patent/ZA81631B/xx unknown
- 1981-01-30 NO NO810338A patent/NO810338L/no unknown
- 1981-01-30 IE IE176/81A patent/IE50888B1/en unknown
- 1981-01-30 CA CA000369739A patent/CA1146540A/en not_active Expired
- 1981-01-30 ZW ZW22/81A patent/ZW2281A1/xx unknown
- 1981-01-30 ES ES498989A patent/ES498989A0/es active Granted
- 1981-01-31 JP JP1226281A patent/JPS56122382A/ja active Pending
- 1981-01-31 KR KR1019810000311A patent/KR840000502B1/ko active
Also Published As
Publication number | Publication date |
---|---|
MC1367A1 (fr) | 1981-10-23 |
PL125899B1 (en) | 1983-06-30 |
GR78221B (it) | 1984-09-26 |
IE810176L (en) | 1981-08-01 |
ES8204439A1 (es) | 1982-05-01 |
KR830005235A (ko) | 1983-08-03 |
DD157462A5 (de) | 1982-11-10 |
IL62017A0 (en) | 1981-02-27 |
ES498989A0 (es) | 1982-05-01 |
SU1036250A1 (ru) | 1983-08-15 |
IE50888B1 (en) | 1986-08-06 |
PT72421A (de) | 1981-02-01 |
EP0033518A1 (de) | 1981-08-12 |
OA06732A (fr) | 1982-06-30 |
CA1146540A (en) | 1983-05-17 |
CS219851B2 (en) | 1983-03-25 |
AU6677981A (en) | 1981-08-06 |
IL62017A (en) | 1984-06-29 |
NO810338L (no) | 1981-08-03 |
DK32081A (da) | 1981-08-02 |
ATE3550T1 (de) | 1983-06-15 |
EP0033518B1 (de) | 1983-05-25 |
ZW2281A1 (en) | 1981-09-02 |
NZ196159A (en) | 1983-09-30 |
DE3160328D1 (en) | 1983-07-07 |
PL229457A1 (it) | 1981-10-02 |
MTP882B (en) | 1984-06-05 |
KR840000502B1 (ko) | 1984-04-16 |
US4411897A (en) | 1983-10-25 |
ZA81631B (en) | 1982-02-24 |
FI810270L (fi) | 1981-08-02 |
JPS56122382A (en) | 1981-09-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5407929A (en) | Triazolylthiomethylthio cephalosporin hydrochhloride, its crystalline hydrate and the production of the same | |
FI76093B (fi) | Foerfarande foer framstaellning av en amorf form av 1-acetoxietylester av (6r,7r)-3-karbamoyloximetyl-7- /(z)-2-(fur-2-yl)-2-metoxiiminoacetamido/cef-3-em-4-karboxylsyra eller cefuroximaxetil. | |
FI65623C (fi) | Foerfarande foer framstaellning av antibiotiskt aktiv (6r 7r)-3-karbamoyloximetyl-7-(2-(fur-2-yl)-2-metoxiiminoacetamido)-cef-3-em-4-karboxylsyra samt dennas icke-giftiga salter | |
JP5852562B2 (ja) | 新規なセフェム誘導体 | |
JPS5858354B2 (ja) | セフェム誘導体 | |
HU184835B (en) | Process for preparing crystallic pentahydrate of cefem-carboxylic acid derivatives | |
FI66874B (fi) | Foerfarande foer framstaellning av kristallina salter av 7beta-(2-(2-amino-4-tiazolyl)-2-metoxi-iminoacetamido)-3-cefem-4-karboxylsyra-pivaloyloximetylester | |
FI67385B (fi) | Foerfarande foer framstaellning av (6r,7r)-7-(2-(2-amino-4-tiazolyl)-2-(z-metoxiimino)acetamido)-3-cefem-4-karboxylsyraderivat | |
FI65069C (fi) | Foerfarande foer framstaellning av kristallvattenfri ny-kristallin form av natrium-7-(d-alfa-formyloxi-alfa-fenylacetamido)-3-(1-metyl-1h-tetrazol-5-yltiometyl)-3-cefem-4-karboxylat | |
EP0264091B1 (en) | 3-propenylcephem derivative, preparation thereof, chemical intermediates therein, pharmaceutical composition and use | |
DE3500090A1 (de) | Cephalosporin-antibiotika | |
US8916526B2 (en) | Flavanone derivative | |
US4189479A (en) | Cephalosporin esters | |
KR910008350B1 (ko) | 세팔로스포린 에스테르 유도체의 제조방법 | |
KR830001130B1 (ko) | 세팔로스포린 항생제의 제조방법 | |
US4959469A (en) | Crystalline cephalosporin compounds | |
US4734408A (en) | Crystalline cephalosporin antibiotic salts and solvates | |
FI83877C (fi) | Foerfarande foer framstaellning av en ny terapeutiskt anvaendbar 7-(3-klorisoxazol-5-yl)-acetamido-3- (1-metyl-1h-1,2,3,4-tetrazol-5-yl)-tiometyl-cef-3-em-4-karboxylsyra | |
JP2575590B2 (ja) | トリアゾリルチオメチルチオセファロスポリン塩酸塩およびその水和物結晶ならびにそれらの製法 | |
US5068322A (en) | Crystalline cephalosporin compounds | |
HU182498B (en) | Process for producing 7-bracket-iminoacetamido-bracket closed-3-thiomethyl-ceph-3-eme-4-caraoxylic acid | |
EP0883621A1 (en) | Cephalosporin derivatives and processes for the preparation thereof | |
CN111187285B (zh) | 氟氧头孢钠的晶型、制备方法、药物组合物及应用 | |
KR950010084B1 (ko) | 결정성 세팔로스포린 화합물, 그의 제조법 및 그의 제조 중간체 | |
PT93352A (pt) | Processo para a preparacao de compostos beta-lactamicos |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Application withdrawn |
Owner name: CIBA-GEIGY AG |