FI20155280A - Aivovamman prognostisia ja diagnostisia glykaanipohjaisia biomarkkereita - Google Patents
Aivovamman prognostisia ja diagnostisia glykaanipohjaisia biomarkkereita Download PDFInfo
- Publication number
- FI20155280A FI20155280A FI20155280A FI20155280A FI20155280A FI 20155280 A FI20155280 A FI 20155280A FI 20155280 A FI20155280 A FI 20155280A FI 20155280 A FI20155280 A FI 20155280A FI 20155280 A FI20155280 A FI 20155280A
- Authority
- FI
- Finland
- Prior art keywords
- glycan
- prognostic
- diagnostic
- brain injury
- based biomarkers
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
- C07K14/42—Lectins, e.g. concanavalin, phytohaemagglutinin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/415—Assays involving biological materials from specific organisms or of a specific nature from plants
- G01N2333/42—Lectins, e.g. concanavalin, phytohaemagglutinin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/12—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20155280A FI20155280A (fi) | 2015-04-15 | 2015-04-15 | Aivovamman prognostisia ja diagnostisia glykaanipohjaisia biomarkkereita |
| DK16721191.1T DK3283880T3 (da) | 2015-04-15 | 2016-04-14 | Prognostiske og diagnostiske glycan-baserede biomarkører af hjerneskade |
| CA2982503A CA2982503C (en) | 2015-04-15 | 2016-04-14 | Prognostic and diagnostic glycan-based biomarkers of brain damage |
| ES16721191T ES2800039T3 (es) | 2015-04-15 | 2016-04-14 | Biomarcadores de prognóstico y de diagnóstico de lesiones cerebrales basados en glicanos |
| US15/565,753 US10739335B2 (en) | 2015-04-15 | 2016-04-14 | Prognostic and diagnostic glycan-based biomarkers of brain damage |
| EP16721191.1A EP3283880B1 (en) | 2015-04-15 | 2016-04-14 | Prognostic and diagnostic glycan-based biomarkers of brain damage |
| PCT/FI2016/050246 WO2016166419A1 (en) | 2015-04-15 | 2016-04-14 | Prognostic and diagnostic glycan-based biomarkers of brain damage |
| IL254980A IL254980B (en) | 2015-04-15 | 2017-10-10 | Prognostic and diagnostic glycan-based markers for brain damage |
| US16/913,394 US20200371093A1 (en) | 2015-04-15 | 2020-06-26 | Prognostic and Diagnostic Glycan-Based Biomarkers of Brain Damage |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20155280A FI20155280A (fi) | 2015-04-15 | 2015-04-15 | Aivovamman prognostisia ja diagnostisia glykaanipohjaisia biomarkkereita |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI20155280A true FI20155280A (fi) | 2016-10-16 |
Family
ID=55948851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI20155280A FI20155280A (fi) | 2015-04-15 | 2015-04-15 | Aivovamman prognostisia ja diagnostisia glykaanipohjaisia biomarkkereita |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10739335B2 (fi) |
| EP (1) | EP3283880B1 (fi) |
| CA (1) | CA2982503C (fi) |
| DK (1) | DK3283880T3 (fi) |
| ES (1) | ES2800039T3 (fi) |
| FI (1) | FI20155280A (fi) |
| IL (1) | IL254980B (fi) |
| WO (1) | WO2016166419A1 (fi) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2018102138A6 (en) | 2017-02-21 | 2019-09-19 | Medicortex Finland Oy | Non-invasive brain injury diagnostic device |
| US11016092B2 (en) | 2017-03-23 | 2021-05-25 | Abbott Laboratories | Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase L1 |
| WO2018191531A1 (en) | 2017-04-15 | 2018-10-18 | Abbott Laboratories | Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury in a human subject using early biomarkers |
| BR112019022476A2 (pt) | 2017-04-28 | 2020-05-12 | Abbott Laboratories | Métodos para o auxílio no diagnóstico e determinação hiperagudos de lesão cerebral traumática usando biomarcadores iniciais em pelo menos duas amostras a partir do mesmo ser humano |
| CA3078725A1 (en) | 2017-05-25 | 2018-11-29 | Abbott Laboratories | Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers |
| BR112019025313A2 (pt) | 2017-05-30 | 2020-06-23 | Abbott Laboratories | Métodos para auxílio no diagnóstico e avaliação de uma lesão cerebral traumática leve em um indivíduo humano usando troponina cardíaca i |
| EP3649474A1 (en) | 2017-07-03 | 2020-05-13 | Abbott Laboratories | Improved methods for measuring ubiquitin carboxy-terminal hydrolase l1 levels in blood |
| EP3721228A4 (en) * | 2017-12-06 | 2021-12-15 | Flotbi Inc. | ASSAY AND POINT OF CARE DEVICE USING SALIVA FOR DIAGNOSIS AND TREATMENT OF NEUROLOGICAL CONDITIONS AFFECTING BRAIN HEALTH |
| US11016105B2 (en) | 2017-12-09 | 2021-05-25 | Abbott Laboratories | Methods for aiding in diagnosing and evaluating a traumatic brain injury in a human subject using a combination of GFAP and UCH-L1 |
| EP3721233A2 (en) | 2017-12-09 | 2020-10-14 | Abbott Laboratories | Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (tbi), using glial fibrillary acidic protein (gfap) and/or ubiquitin carboxy-terminal hydrolase l1 (uch-l1) |
| EP3732489A1 (en) * | 2017-12-29 | 2020-11-04 | Abbott Laboratories | Novel biomarkers and methods for diagnosing and evaluating traumatic brain injury |
| US20220214362A1 (en) * | 2019-05-10 | 2022-07-07 | Abbott Laboratories | Evaluating biomarkers along with advanced magnetic resonance imaging procedures in a human subject that has sustained or may have sustained a head injury |
| FI20196004A1 (fi) * | 2019-11-22 | 2021-05-23 | Medicortex Finland Oy | Laite ja menetelmä kohteen aivovamman detektoimiseksi |
| US20210311043A1 (en) | 2020-04-06 | 2021-10-07 | Medicortex Finland Oy | Method for determining a lectin-binding glycan indicative to traumatic brain injury |
| WO2021236050A1 (en) | 2020-05-18 | 2021-11-25 | Baseline Global, Inc. | Assay device, system, method, and kit |
| FI130428B (fi) * | 2022-02-22 | 2023-08-24 | Medicortex Finland Oy | Menetelmä kudosvaurion havaitsemiseksi |
| DE202023100246U1 (de) | 2022-04-05 | 2023-04-21 | Medicortex Finland Oy | Eine in der Hand haltbare Vorrichtung zum Sammeln und Testen von flüssigen Proben |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2651581B1 (fr) | 1989-09-06 | 1994-05-13 | Centre Nal Recherc Scientifique | Moyens pour le diagnostic de neuropathies demyelinisantes, en particulier de la sclerose en plaques. |
| GB2404734A (en) * | 2003-08-05 | 2005-02-09 | Secr Defence | A method of screening a sample for abnormally glycosylated and/or expressed proteins |
| US20060166290A1 (en) | 2004-01-15 | 2006-07-27 | Yale University | Primary central nervous system tumor specific BEHAB isoforms |
| US7838634B2 (en) | 2005-04-15 | 2010-11-23 | Van Andel Research Institute | Methods for measuring glycan levels of proteins |
| JP4385149B2 (ja) | 2005-05-11 | 2009-12-16 | 独立行政法人理化学研究所 | 血清糖蛋白質をバイオマーカーとするアルツハイマー病の診断薬 |
| GB2428240A (en) * | 2005-07-14 | 2007-01-24 | Univ Gen Ve | Diagnostic method for brain damage-related disorders |
| JP5207469B2 (ja) | 2006-09-06 | 2013-06-12 | 国立大学法人鳥取大学 | アルツハイマーの診断キット、診断マーカー及び病態指標の検出方法 |
| US20150369825A1 (en) * | 2013-02-26 | 2015-12-24 | Sophia SCHEDIN WEISS | Diagnosis of Alzheimer Disease, Cognitive Decline and Dementia |
| US10534003B2 (en) * | 2013-07-17 | 2020-01-14 | The Johns Hopkins University | Multi-protein biomarker assay for brain injury detection and outcome |
| WO2015130956A2 (en) | 2014-02-28 | 2015-09-03 | Exosome Sciences, Inc. | Brain specific exosome based diagnostics and extracorporeal therapies |
-
2015
- 2015-04-15 FI FI20155280A patent/FI20155280A/fi not_active Application Discontinuation
-
2016
- 2016-04-14 US US15/565,753 patent/US10739335B2/en active Active
- 2016-04-14 EP EP16721191.1A patent/EP3283880B1/en active Active
- 2016-04-14 ES ES16721191T patent/ES2800039T3/es active Active
- 2016-04-14 DK DK16721191.1T patent/DK3283880T3/da active
- 2016-04-14 WO PCT/FI2016/050246 patent/WO2016166419A1/en active Application Filing
- 2016-04-14 CA CA2982503A patent/CA2982503C/en active Active
-
2017
- 2017-10-10 IL IL254980A patent/IL254980B/en unknown
-
2020
- 2020-06-26 US US16/913,394 patent/US20200371093A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL254980B (en) | 2021-07-29 |
| IL254980A0 (en) | 2017-12-31 |
| US10739335B2 (en) | 2020-08-11 |
| CA2982503A1 (en) | 2016-10-20 |
| CA2982503C (en) | 2021-07-13 |
| US20180120305A1 (en) | 2018-05-03 |
| WO2016166419A1 (en) | 2016-10-20 |
| US20200371093A1 (en) | 2020-11-26 |
| EP3283880B1 (en) | 2020-04-15 |
| DK3283880T3 (da) | 2020-06-29 |
| ES2800039T3 (es) | 2020-12-23 |
| EP3283880A1 (en) | 2018-02-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |