FI20020184A - Still to detect the RS virus - Google Patents

Still to detect the RS virus Download PDF

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Publication number
FI20020184A
FI20020184A FI20020184A FI20020184A FI20020184A FI 20020184 A FI20020184 A FI 20020184A FI 20020184 A FI20020184 A FI 20020184A FI 20020184 A FI20020184 A FI 20020184A FI 20020184 A FI20020184 A FI 20020184A
Authority
FI
Finland
Prior art keywords
pct
monoclonal antibodies
sec
disclosed
virus
Prior art date
Application number
FI20020184A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI111553B (en
Inventor
Dennis R Burton
Carlos F Barbas Iii
Robert M Chanock
Brian R Murphy
James E Crowe Jr
Original Assignee
Scripps Research Inst
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst, Us Gov Health & Human Serv filed Critical Scripps Research Inst
Publication of FI20020184A publication Critical patent/FI20020184A/en
Application granted granted Critical
Publication of FI111553B publication Critical patent/FI111553B/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1006—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being against or targeting material from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

PCT No. PCT/US93/08786 Sec. 371 Date Jan. 27, 1994 Sec. 102(e) Date Jan. 27, 1994 PCT Filed Sep. 16, 1993 PCT Pub. No. WO94/06448 PCT Pub. Date Mar. 31, 1994Human monoclonal antibodies and fragments thereof which bind and neutralize respiratory syncytial virus (RSV) antigenic subgroups A and B are disclosed. Also disclosed are diagnostic and immunotherapeutic methods of using the monoclonal antibodies as well as cell lines producing the monoclonal antibodies.
FI20020184A 1992-09-16 2002-01-31 Procedure for detecting the RS virus FI111553B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US94551592A 1992-09-16 1992-09-16
US94551592 1992-09-16
PCT/US1993/008786 WO1994006448A1 (en) 1992-09-16 1993-09-16 Human neutralizing monoclonal antibodies to respiratory syncytial virus
US9308786 1993-09-16

Publications (2)

Publication Number Publication Date
FI20020184A true FI20020184A (en) 2002-01-31
FI111553B FI111553B (en) 2003-08-15

Family

ID=25483204

Family Applications (2)

Application Number Title Priority Date Filing Date
FI951164A FI108991B (en) 1992-09-16 1995-03-13 A method of producing a human monoclonal antibody
FI20020184A FI111553B (en) 1992-09-16 2002-01-31 Procedure for detecting the RS virus

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI951164A FI108991B (en) 1992-09-16 1995-03-13 A method of producing a human monoclonal antibody

Country Status (12)

Country Link
US (1) US5762905A (en)
EP (1) EP0671927B1 (en)
JP (1) JP3976333B2 (en)
AT (1) ATE231002T1 (en)
AU (1) AU686113B2 (en)
CA (1) CA2144043C (en)
DE (1) DE69332643T2 (en)
DK (1) DK0671927T3 (en)
ES (1) ES2191016T3 (en)
FI (2) FI108991B (en)
NO (1) NO323768B1 (en)
WO (1) WO1994006448A1 (en)

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US5811524A (en) * 1995-06-07 1998-09-22 Idec Pharmaceuticals Corporation Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof
AU7075496A (en) * 1995-09-18 1997-04-09 Intracel Corporation Neutralizing monoclonal antibodies to respiratory syncytial virus
WO1998019704A1 (en) * 1996-11-01 1998-05-14 Smithkline Beecham Corporation Human monoclonal antibodies
ITRM960808A1 (en) * 1996-11-26 1998-05-26 Rossolini Gianmaria IMMUNOCONJUGATES INCLUDING HUMAN MONOCLONAL ANTIBODIES OR FRAGMENTS THEREOF FOR IN VIVO DIAGNOSIS AND THERAPY
FR2758331B1 (en) * 1997-01-14 1999-03-05 Univ Bourgogne NEW MEANS FOR DIAGNOSIS, PREVENTION AND TREATMENT FOR CONTAMINATION OR INFECTIONS WITH MUCOUS TROPISM VIRUSES
ATE276763T1 (en) 1998-07-13 2004-10-15 Univ Texas USE OF ANTIBODIES TO AMINOPHOSPHOLIPIDES FOR CANCER TREATMENT
AR030019A1 (en) * 1999-05-18 2003-08-13 Smithkline Beecham Corp HUMAN MONOCLONAL ANTIBODIES AND FUNCTIONAL FRAGMENTS OF THE SAME, A PROCEDURE FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM, A NUCLEIC ACID ISOLATED MOLECULA, A RECOMBINANT PLASMIDE, A HOSPED DIFFERENT USE OF A MUSCLE
DE60142614D1 (en) * 2000-01-27 2010-09-02 Medimmune Inc INITÄT
US7229619B1 (en) 2000-11-28 2007-06-12 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
DK1259547T3 (en) 2000-03-01 2012-10-15 Medimmune Inc HIGH POTENTIAL, RECOMBINANT ANTIBODIES AND PROCEDURE FOR PRODUCING THEM
US20050175986A1 (en) * 2000-05-09 2005-08-11 Smit Kline Beecham Corporation Human monoclonal antibody
JP2004511807A (en) * 2000-10-17 2004-04-15 ベッスト−テスト　アンパーツゼルスカブ Assay for direct detection of biological cells associated with respiratory syncytial virus in body fluid samples
US7179900B2 (en) 2000-11-28 2007-02-20 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US6855493B2 (en) 2000-11-28 2005-02-15 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
WO2003063767A2 (en) * 2001-11-02 2003-08-07 Centocor Rsv proteins, antibodies, compositions, methods and uses
US7132100B2 (en) * 2002-06-14 2006-11-07 Medimmune, Inc. Stabilized liquid anti-RSV antibody formulations
US7425618B2 (en) 2002-06-14 2008-09-16 Medimmune, Inc. Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
US6919077B2 (en) * 2002-09-27 2005-07-19 Aids Research, Llc LFA-1 alpha subunit antibodies and methods of use
US7070786B2 (en) 2003-06-06 2006-07-04 Centocor, Inc. RSV proteins, antibodies, compositions, methods and uses
WO2005060520A2 (en) * 2003-11-25 2005-07-07 Dana-Farber Cancer Institute, Inc. ANTIBODIES AGAINST SARS-CoV AND METHODS OF USE THEREOF
JP2008513540A (en) 2004-09-21 2008-05-01 メディミューン，インコーポレーテッド Antibody to respiratory syncytial virus and method for producing vaccine for the virus
US20060115485A1 (en) * 2004-10-29 2006-06-01 Medimmune, Inc. Methods of preventing and treating RSV infections and related conditions
AU2007222798A1 (en) * 2006-03-06 2007-09-13 Symphogen A/S Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections
PL2066351T3 (en) 2006-10-02 2016-02-29 Squibb & Sons Llc Human antibodies that bind cxcr4 and uses thereof
MX2009005776A (en) 2006-12-01 2009-06-10 Medarex Inc Human antibodies that bind cd22 and uses thereof.
CL2007003622A1 (en) 2006-12-13 2009-08-07 Medarex Inc Human anti-cd19 monoclonal antibody; composition comprising it; and tumor cell growth inhibition method.
IN2009KN02404A (en) 2006-12-14 2015-08-07 Medarex Inc
RU2009136677A (en) * 2007-03-06 2011-04-20 Симфоген А/С (Dk) RECOMBINANT ANTIBODIES FOR TREATMENT OF RESPIRATORY SYNCITIAL VIRAL INFECTIONS
EP1997830A1 (en) 2007-06-01 2008-12-03 AIMM Therapeutics B.V. RSV specific binding molecules and means for producing them
AR072999A1 (en) 2008-08-11 2010-10-06 Medarex Inc HUMAN ANTIBODIES THAT JOIN GEN 3 OF LYMPHOCYTARY ACTIVATION (LAG-3) AND THE USES OF THESE
WO2010087927A2 (en) 2009-02-02 2010-08-05 Medimmune, Llc Antibodies against and methods for producing vaccines for respiratory syncytial virus
US20110033389A1 (en) * 2009-04-29 2011-02-10 Zhifeng Chen Modified antibodies for passive immunotherapy
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CL2011003002A1 (en) 2011-11-25 2012-05-25 Univ Pontificia Catolica Chile Monoclonal antibody or a fragment thereof that binds to the m2-1 protein of the human respiratory syncytial virus (RSV); nucleotide sequences; pharmaceutical composition; method of diagnosis of infection produced by vrs; kit; and use of said antibody to prepare a medicament.
AR091649A1 (en) 2012-07-02 2015-02-18 Bristol Myers Squibb Co OPTIMIZATION OF ANTIBODIES THAT FIX THE LYMPHOCYTE ACTIVATION GEN 3 (LAG-3) AND ITS USES
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JP7265984B2 (en) 2016-10-21 2023-04-27 アディマブ， エルエルシー Anti-respiratory syncytial virus antibodies and methods of their production and use
JP2020503843A (en) 2016-10-21 2020-02-06 アディマブ， エルエルシー Anti-respiratory syncytial virus antibodies and methods for their production and use
US11845798B2 (en) 2017-05-02 2023-12-19 Merck Sharp & Dohme Llc Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies
JOP20190260A1 (en) 2017-05-02 2019-10-31 Merck Sharp & Dohme Stable formulations of programmed death receptor 1 (pd-1) antibodies and methods of use thereof
SG11202100746WA (en) 2018-07-25 2021-03-30 Innovent Biologics Suzhou Co Ltd Anti-tigit antibody and use thereof
CN109762067B (en) 2019-01-17 2020-02-28 北京天广实生物技术股份有限公司 Antibodies that bind human Claudin18.2 and uses thereof
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Also Published As

Publication number Publication date
AU686113B2 (en) 1998-02-05
FI951164A0 (en) 1995-03-13
CA2144043C (en) 2005-01-18
NO323768B1 (en) 2007-07-02
EP0671927B1 (en) 2003-01-15
WO1994006448A1 (en) 1994-03-31
CA2144043A1 (en) 1994-03-31
DK0671927T3 (en) 2003-04-22
EP0671927A1 (en) 1995-09-20
NO950881L (en) 1995-05-15
JPH08505520A (en) 1996-06-18
EP0671927A4 (en) 1997-05-21
JP3976333B2 (en) 2007-09-19
FI108991B (en) 2002-05-15
US5762905A (en) 1998-06-09
FI951164A (en) 1995-05-12
NO950881D0 (en) 1995-03-07
ATE231002T1 (en) 2003-02-15
ES2191016T3 (en) 2003-09-01
FI111553B (en) 2003-08-15
AU4927193A (en) 1994-04-12
DE69332643D1 (en) 2003-02-20
DE69332643T2 (en) 2003-11-27

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