ES8801670A1 - Un procedimiento para preparar nuevos compuestos de 2-oxa pregnano. - Google Patents
Un procedimiento para preparar nuevos compuestos de 2-oxa pregnano.Info
- Publication number
- ES8801670A1 ES8801670A1 ES557572A ES557572A ES8801670A1 ES 8801670 A1 ES8801670 A1 ES 8801670A1 ES 557572 A ES557572 A ES 557572A ES 557572 A ES557572 A ES 557572A ES 8801670 A1 ES8801670 A1 ES 8801670A1
- Authority
- ES
- Spain
- Prior art keywords
- aza
- oxa
- image
- group
- pregnane compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
- C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
- C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
- C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
- C07J73/003—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by oxygen as hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE COMPUESTOS DE 2-OXA-PREGNANO, DE FORMULA GENERAL (I). CONSISTE EN REDUCIR EN EL SENO DE UN DISOLVENTE, UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE A REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO ALCANOILO INFERIOR; Z REPRESENTA UN ATOMO DE OXIGENO; Y X REPRESENTA UN ATOMO DE HALOGENO, A UNA TEMPERATURA COMPRENDIDA ENTRE C20 GRADOS Y LA TEMPERATURA AMBIENTE, EMPLEANDO UN HIDRURO METALICO COMPLEJO EN CALIDAD DE AGENTE REDUCTOR. DE APLICACION EN LA PREPARACION DE FARMACOS PARA EVITAR EL ABORTO O PARA LA CONTRACEPCION.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60043731A JPS61204198A (ja) | 1985-03-07 | 1985-03-07 | 2−オキサプレグナン化合物 |
JP4373285A JPS61204199A (ja) | 1985-03-07 | 1985-03-07 | 2−アザプレグナン化合物 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8801670A1 true ES8801670A1 (es) | 1988-02-16 |
ES557572A0 ES557572A0 (es) | 1988-02-16 |
Family
ID=26383560
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES552724A Expired ES8801669A1 (es) | 1985-03-07 | 1986-03-06 | Un procedimiento para preparar nuevos compuestos de 2-oxa-0 aza-pregnano. |
ES557573A Expired ES8801928A1 (es) | 1985-03-07 | 1987-05-29 | Un procedimiento para preparar nuevos compuestos de 2-oxa pregnano. |
ES557572A Expired ES8801670A1 (es) | 1985-03-07 | 1987-05-29 | Un procedimiento para preparar nuevos compuestos de 2-oxa pregnano. |
ES557574A Expired ES8801510A1 (es) | 1985-03-07 | 1987-05-29 | Un procedimiento para preparar nuevos compuestos de 2-oxa-o -aza-pregnano |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES552724A Expired ES8801669A1 (es) | 1985-03-07 | 1986-03-06 | Un procedimiento para preparar nuevos compuestos de 2-oxa-0 aza-pregnano. |
ES557573A Expired ES8801928A1 (es) | 1985-03-07 | 1987-05-29 | Un procedimiento para preparar nuevos compuestos de 2-oxa pregnano. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES557574A Expired ES8801510A1 (es) | 1985-03-07 | 1987-05-29 | Un procedimiento para preparar nuevos compuestos de 2-oxa-o -aza-pregnano |
Country Status (8)
Country | Link |
---|---|
US (2) | US4785103A (es) |
EP (1) | EP0193871B1 (es) |
AU (1) | AU576945B2 (es) |
CA (1) | CA1255293A (es) |
DE (1) | DE3663668D1 (es) |
ES (4) | ES8801669A1 (es) |
IN (1) | IN162700B (es) |
NZ (1) | NZ215328A (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0193871B1 (en) * | 1985-03-07 | 1989-05-31 | Teikoku Hormone Mfg. Co., Ltd. | 2-oxa- or aza-pregnane compounds |
US20020091155A1 (en) * | 1995-06-22 | 2002-07-11 | Btg Pharmaceutical Corp. | Method for ameliorating muscle weakness/wasting in a patient infected with human immunodeficiency virus-type 1 |
US5872147A (en) * | 1996-12-05 | 1999-02-16 | Bio-Technology General Corp. | Use of oxandrolone in the treatment of chronic obstructive pulmonary disease |
CN1290507C (zh) * | 2000-12-14 | 2006-12-20 | 奥索-麦克尼尔药品公司 | 甾类激素产品及其制备方法 |
BR112018071950A2 (pt) | 2016-05-11 | 2019-02-05 | Aska Pharm Co Ltd | forma polimórfica cristalina a de acetato de 15¿-hidróxi-osaterona, processo para a produção de uma forma polimórfica cristalina a de acetato de 15¿-hidróxi-osaterona, e composição farmacêutica |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3179658A (en) * | 1961-05-26 | 1965-04-20 | Merck & Co Inc | 2-oxa steroids and processes of preparing the same |
US3093658A (en) * | 1961-10-16 | 1963-06-11 | Searle & Co | 17alpha, 21-dihydroxy-2-oxapregnane-3, 11, 20-trione, esters thereof and intermediates thereto |
US3080381A (en) * | 1962-02-16 | 1963-03-05 | Searle & Co | Optionally 6-methylated and optionally 17-alkanoyloxygenated 2-oxapregnane-3, 20-diones, a-homo compounds corresponding, and 4, 5-dehydro and 4, 5; 6, 7-bisdehydro derivatives thereof |
GB990656A (en) * | 1962-04-23 | 1965-04-28 | Searle & Co | Compounds of the androstane series |
US3280133A (en) * | 1964-10-12 | 1966-10-18 | Searle & Co | (optionally alkylated)-2-aza-5alpha-androstan-17beta-ols and acyl derivatives thereof |
US3526642A (en) * | 1968-06-19 | 1970-09-01 | Squibb & Sons Inc | 2-oxa-5beta-cyanopregnane derivatives |
EP0193871B1 (en) * | 1985-03-07 | 1989-05-31 | Teikoku Hormone Mfg. Co., Ltd. | 2-oxa- or aza-pregnane compounds |
GB8505862D0 (en) * | 1985-03-07 | 1985-04-11 | Erba Farmitalia | Steroidic 5alpha-reductase inhibitors |
-
1986
- 1986-02-27 EP EP86102537A patent/EP0193871B1/en not_active Expired
- 1986-02-27 US US06/833,715 patent/US4785103A/en not_active Expired - Lifetime
- 1986-02-27 DE DE8686102537T patent/DE3663668D1/de not_active Expired
- 1986-02-28 NZ NZ215328A patent/NZ215328A/xx unknown
- 1986-03-04 AU AU54245/86A patent/AU576945B2/en not_active Expired
- 1986-03-06 CA CA000503465A patent/CA1255293A/en not_active Expired
- 1986-03-06 ES ES552724A patent/ES8801669A1/es not_active Expired
- 1986-03-07 IN IN156/MAS/86A patent/IN162700B/en unknown
-
1987
- 1987-05-29 ES ES557573A patent/ES8801928A1/es not_active Expired
- 1987-05-29 ES ES557572A patent/ES8801670A1/es not_active Expired
- 1987-05-29 ES ES557574A patent/ES8801510A1/es not_active Expired
-
1988
- 1988-08-04 US US07/228,316 patent/US4914106A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES8801669A1 (es) | 1988-02-16 |
US4914106A (en) | 1990-04-03 |
CA1255293A (en) | 1989-06-06 |
ES8801928A1 (es) | 1988-03-01 |
DE3663668D1 (de) | 1989-07-06 |
ES552724A0 (es) | 1988-02-16 |
AU5424586A (en) | 1986-09-11 |
ES8801510A1 (es) | 1988-01-16 |
EP0193871A3 (en) | 1986-11-20 |
EP0193871A2 (en) | 1986-09-10 |
NZ215328A (en) | 1988-09-29 |
AU576945B2 (en) | 1988-09-08 |
US4785103A (en) | 1988-11-15 |
ES557572A0 (es) | 1988-02-16 |
IN162700B (es) | 1988-07-02 |
ES557574A0 (es) | 1988-01-16 |
EP0193871B1 (en) | 1989-05-31 |
ES557573A0 (es) | 1988-03-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20071126 |